PSQ01151
FD00028
Albumin-8
P23110
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae asterids campanulids Asterales Asteraceae Asteroideae Heliantheae alliance Heliantheae Helianthus
Helianthus annuus (Common sunflower)
13
nutrient reservoir activity
141
Methionine-rich 2S protein, SFA8
None
4232
None
None
1997318, 8915004
13
26:38
STTTIITTIIEEN
PSQ01152
FD00358
Photosystem I reaction center subunit PsaK
P23317
Bacteria Cyanobacteria Nostocales Nostocaceae Trichormus
Trichormus variabilis (strain ATCC 29413
8
None
86
Light-harvesting 6, Photosystem I subunit X
psaK
240292
integral component of membrane, photosystem I, plasma membrane-derived thylakoid membrane
photosynthesis
1908790
8
1:8
MLTSTLLA
PSQ01153
FD00125
Brain-derived neurotrophic factor
P23560
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
110
growth factor activity, nerve growth factor receptor binding
247
Abrineurin
BDNF
9606
axon, cytoplasm, dendrite, extracellular region, extracellular space, mitochondrion, nuclear speck, perinuclear region of cytoplasm, synaptic vesicle
activation of phospholipase C activity, axon guidance, brain-derived neurotrophic factor receptor signaling pathway, collateral sprouting, memory, modulation of chemical synaptic transmission, negative regulation of apoptotic signaling pathway, negative regulation of myotube differentiation, negative regulation of neuron apoptotic process, nerve development, nerve growth factor signaling pathway, nervous system development, neuron projection morphogenesis, neurotrophin TRK receptor signaling pathway, peripheral nervous system development, positive regulation of brain-derived neurotrophic factor receptor signaling pathway, positive regulation of collateral sprouting, positive regulation of neuron projection development, positive regulation of non-membrane spanning protein tyrosine kinase activity, positive regulation of peptidyl-serine phosphorylation, positive regulation of receptor binding, positive regulation of synapse assembly, regulation of neuron differentiation, regulation of protein localization to cell surface, synapse assembly, transmembrane receptor protein tyrosine kinase signaling pathway
8527932
110
19:128
APMKEANIRGQGGLAYPGVRTHGTLESVNGPKAGSRGLTSLADTFEHVIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRR
PSQ01154
FD00207
Glucan 1
P23776
Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces
Saccharomyces cerevisiae (strain ATCC 204508
21
beta-glucosidase activity, glucan exo-1,3-beta-glucosidase activity
448
Exo-1, Soluble cell wall protein 6
EXG1
559292
cell surface, extracellular region, fungal-type cell wall, fungal-type vacuole
cellular glucan metabolic process, fungal-type cell wall organization, glucan catabolic process
1900250, 2125957, 8488724, 9748433
21
20:40
TPVPARDPSSIQFVHEENKKR
PSQ01155
FND00304
Bacteriocin lactacin-F subunit LafA
P24022
Bacteria Firmicutes Bacilli Lactobacillales Lactobacillaceae Lactobacillus
Lactobacillus johnsonii (strain CNCM I-12250
18
None
75
None
lafA
257314
None
cytolysis, defense response to bacterium
1903624
18
1:18
MKQFNYLSHKDLAVVVGG
PSQ01156
FD00003
Gamma-conotoxin-like TxVIIA
P24160
Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Neogastropoda Conoidea Conidae Conus Cylinder
Conus textile (Cloth-of-gold cone)
27
ion channel inhibitor activity, toxin activity
76
TxIIA
None
6494
extracellular region
pathogenesis
1761058
27
20:46
MFQGDGEKSRKAEINFSETRKLARNKQ
PSQ01157
FND00024
Dermaseptin-S1
P24302
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Hylidae Phyllomedusinae Phyllomedusa
Phyllomedusa sauvagei (Sauvage
23
None
79
Dermaseptin , Dermaseptin I , Dermaseptin-1
None
8395
extracellular region
defense response to bacterium, defense response to fungus, innate immune response, killing of cells of other organism, regulation of defense response to virus
1909573, 8306981
23
23:45
EEEKRENEDEEKQEDDEQSEMKR
PSQ01158
FD00257
Aspergillopepsin-2
P24665
Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Circumdati
Aspergillus niger
41, 11
aspartic-type endopeptidase activity
282
Acid protease A, Aspergillopepsin II, Proctase A
None
5061
None
None
1918059;1918059
52
19:59, 99:109
APLTEKRRARKEARAAGKRHSNPPYIPGSDKEILKLNGTTN, GGGYGYWKNKR
PSQ01159
FD00400
Trypsin inhibitor
P24924
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Fabales Fabaceae Caesalpinioideae mimosoid clade Acacieae Acacia
Acacia confusa (Formosa acacia)
133
serine-type endopeptidase inhibitor activity
180
None
ACTI
3809
None
None
1794977
133
137:269
SDDESCKDLGISIDDENNRRLVVKDGHPLAVRFEKAHRSG
PSQ01160
FD00017
Coagulation factor X
P25155
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Archelosauria Archosauria Dinosauria Saurischia Theropoda Coelurosauria Aves Neognathae Galloanserae Galliformes Phasianidae Phasianinae Gallus
Gallus gallus (Chicken)
20, 55
calcium ion binding, serine-type endopeptidase activity
480
Stuart factor, Virus-activating protease
F10
9031
extracellular space
blood coagulation
2174359;2174359
75
21:40, 186:240
EGGVFIKKESADKFLERTKR, SVILPTNSNTNATSDQDVPSTNGSILEEVFTTTTESPTPPPRNGSSITDPNVDTR
PSQ01161
FD00474
Lysozyme M1
P25310
Bacteria Actinobacteria Streptomycetales Streptomycetaceae Streptomyces
Streptomyces globisporus
193
lysozyme activity
300
1
acm
1908
extracellular region
cell wall macromolecule catabolic process, cytolysis, defense response to bacterium, peptidoglycan catabolic process
2341041
193
77:269
ADTSGVQGIDVSHWQGSINWSSVKSAGMSFAYIKATEGTNYKDDRFSANYTNAYNAGIIRGAYHFARPNASSGTAQADYFASNGGGWSRDNRTLPGVLDIEHNPSGAMCYGLSTTQMRTWINDFHARYKARTTRDVVIYTTASWWNTCTGSWNGMAAKSPFWVAHWGVSAPTVPSGFPTWTFWQYSATGRVGG
PSQ01162
FD00083
Cathepsin S
P25326
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Bovinae Bos
Bos taurus (Bovine)
98
collagen binding, cysteine-type endopeptidase activity, fibronectin binding, laminin binding, proteoglycan binding
331
None
CTSS
9913
extracellular space, late endosome, lysosome, phagocytic vesicle
adaptive immune response, antigen processing and presentation of exogenous peptide antigen via MHC class II, basement membrane disassembly, cellular response to thyroid hormone stimulus, collagen catabolic process, immune response, positive regulation of cation channel activity, protein processing, proteolysis involved in cellular protein catabolic process, response to acidic pH
1515067, 1864368, 2044774
98
17:114
HVHRDPTLDHHWDLWKKTYGKQYKEKNEEVARRLIWEKNLKTVTLHNLEHSMGMHSYELGMNHLGDMTSEEVISLMSSLRVPSQWPRNVTYKSDPNQK
PSQ01163
FD00147
Oryzain alpha chain
P25776
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida Liliopsida Poales Poaceae BOP clade Oryzoideae Oryzeae Oryzinae Oryza Oryza sativa
Oryza sativa subsp
107
cysteine-type endopeptidase activity
458
None
None
39947
extracellular space, lysosome
proteolysis involved in cellular protein catabolic process
1885617
107
22:128
DMSIVSYGERSEEEARRLYAEWKAEHGKSYNAVGEEERRYAAFRDNLRYIDEHNAAADAGVHSFRLGLNRFADLTNEEYRDTYLGLRNKPRRERKVSDRYLAADNEA
PSQ01164
FD00489
Cruzipain
P25779
Eukaryota Discoba Euglenozoa Kinetoplastea Metakinetoplastina Trypanosomatida Trypanosomatidae Trypanosoma Schizotrypanum
Trypanosoma cruzi
104
cysteine-type endopeptidase activity
467
Cruzaine, Major cysteine proteinase
None
5693
None
None
2651912
104
19:122
CLVPAATASLHAEETLTSQFAEFKQKHGRVYESAAEEAFRLSVFRENLFLARLHAAANPHATFGVTPFSDLTREEFRSRYHNGAAHFAAAQERARVPVKVEVVG
PSQ01165
FD00106
Endopolygalacturonase II
P26214
Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Circumdati
Aspergillus niger (strain ATCC 1015 , NCTC 3858a
6
polygalacturonase activity
362
Pectinase 2, Polygalacturonase II, Polygalacturonase X2
pgaII
380704
extracellular region
carbohydrate metabolic process, cell wall organization
2226842
6
22:27
SPIEAR
PSQ01166
FD00167
Prosaposin
P26779
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Bovinae Bos
Bos taurus (Bovine)
36, 14
None
525
Proactivator polypeptide
PSAP
9913
extracellular region, extracellular space, late endosome, lysosome
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, epithelial cell differentiation involved in prostate gland development, lysosomal transport, prostate gland growth, regulation of lipid metabolic process, sphingolipid metabolic process
1554743;1554743
50
276:311, 392:405
KEMPMKTLVPAEVVSENVIPALGLVEPIKKDPAPAK, RGLPAATVRVMPRK
PSQ01167
FND00147
Mating pheromone Er-2
P26886
Eukaryota Sar Alveolata Ciliophora Intramacronucleata Spirotrichea Hypotrichia Euplotida Euplotidae Euplotes
Euplotes raikovi
16
mating pheromone activity
75
Euplomone R2
MAT2, MAT9
5938
extracellular region
None
1549567
16
20:35
FRLQSRLRSNMEASAR
PSQ01168
FD00486
Auracyanin-B
P27197
Bacteria Chloroflexi Chloroflexia Chloroflexales Chloroflexineae Chloroflexaceae Chloroflexus
Chloroflexus aurantiacus (strain ATCC 29366
24
copper ion binding, electron transfer activity, oxidoreductase activity
240
None
None
324602
plasma membrane
photosynthetic electron transport chain
1313011
24
57:80
TAGGFVAATPRPTATPRPTAAPAP
PSQ01169
FD00389
Capsid protein
P27406
Viruses Riboviria Orthornavirae Pisuviricota Pisoniviricetes Picornavirales Caliciviridae Vesivirus
Feline calicivirus (strain F9) (FCV)
124
None
671
Coat protein, VP1
CPP76
11981
host cell cytoplasm, T
None
1731695
124
1:124
MCSTCANVLKYYDWDPHFKLVINPNNFLSVGFCSNPLMCCYPELLPEFGTVWDCDRSPLEIYLESILGDDEWASTFDAVDPVVPPMHWGAAGKIFQPHPGVLMHHLIGKVAAGWDPDLPLIRLE
PSQ01170
FD00004
Tryptase
P27435
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Rattus
Rattus norvegicus (Rat)
10
identical protein binding, peptidase activity, serine-type endopeptidase activity
273
Mast cell protease 7, Tryptase alpha, Tryptase
Tpsab1
10116
extracellular space, mast cell granule
extracellular matrix disassembly, proteolysis
1314562, 2036367
10
19:28
APSLAMPREG
PSQ01171
FD00304
Beta-lytic metalloendopeptidase
P27458
Bacteria Proteobacteria Betaproteobacteria Burkholderiales Alcaligenaceae Achromobacter
Achromobacter lyticus
171
metal ion binding, metalloendopeptidase activity
374
Beta-lytic protease
None
224
extracellular region
None
2228973
171
25:195
ARRATAQRRGSGVFYDEMFDFDIDAHLAKHAPHLHKHSEEISHWAGYSGISRSVDRADGAAERAVTPSARRIVRSASWRAPTASARRPARSRWRCASRCTSAIPTRQGAGDAGPRQSAAGAVRAFRRQRAGGRAARRRRVPAGLRPPVQRTAPGQGGFGPLRQGRPGRAAV
PSQ01172
FD00116
Flagellin B1
P27803
Archaea Euryarchaeota Methanomada group Methanococci Methanococcales Methanococcaceae Methanococcus
Methanococcus voltae
12
structural molecule activity
218
None
flaB1
2188
archaeal-type flagellum
archaeal or bacterial-type flagellum-dependent cell motility
2106880
12
1:12
MNIKEFLSNKKG
PSQ01173
FD00116
Flagellin B2
P27804
Archaea Euryarchaeota Methanomada group Methanococci Methanococcales Methanococcaceae Methanococcus
Methanococcus voltae
12
structural molecule activity
216
None
flaB2
2188
archaeal-type flagellum
archaeal or bacterial-type flagellum-dependent cell motility
2106880
12
1:12
MKIKEFMSNKKG
PSQ01174
FD00494
Acyloxyacyl hydrolase
P28039
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
11
acyloxyacyl hydrolase activity, calcium ion binding
575
None
AOAH
9606
cytoplasmic vesicle, extracellular region, intracellular membrane-bounded organelle
fatty acid metabolic process, lipopolysaccharide catabolic process, negative regulation of inflammatory response
1883828
11
24:34
SPANDDQSRPS
PSQ01175
FD00154
Proteasome subunit beta
P28061
Archaea Euryarchaeota Diaforarchaea group Thermoplasmata Thermoplasmatales Thermoplasmataceae Thermoplasma
Thermoplasma acidophilum (strain ATCC 25905 , 15155
8
endopeptidase activity, threonine-type endopeptidase activity
211
20S proteasome beta subunit , Proteasome core protein PsmB
psmB
273075
cytoplasm, proteasome core complex, beta-subunit complex
proteasomal protein catabolic process
8999862
8
1:8
MNQTLETG
PSQ01176
FD00142
Proteasome subunit beta type-4
P28070
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
45
endopeptidase activity, lipopolysaccharide binding, threonine-type endopeptidase activity
264
26 kDa prosomal protein, Macropain beta chain, Multicatalytic endopeptidase complex beta chain, Proteasome beta chain, Proteasome chain 3
PSMB4
9606
ciliary basal body, cytoplasm, cytosol, extracellular exosome, mitochondrion, nucleoplasm, nucleus, proteasome complex, proteasome core complex, proteasome core complex, beta-subunit complex
anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, Fc-epsilon receptor signaling pathway, interleukin-1-mediated signaling pathway, MAPK cascade, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, negative regulation of inflammatory response to antigenic stimulus, NIK/NF-kappaB signaling, positive regulation of canonical Wnt signaling pathway, post-translational protein modification, pre-replicative complex assembly, proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, protein deubiquitination, protein polyubiquitination, regulation of cellular amino acid metabolic process, regulation of hematopoietic stem cell differentiation, regulation of mitotic cell cycle phase transition, regulation of mRNA stability, regulation of transcription from RNA polymerase II promoter in response to hypoxia, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, stimulatory C-type lectin receptor signaling pathway, T cell receptor signaling pathway, transmembrane transport, tumor necrosis factor-mediated signaling pathway, viral process, Wnt signaling pathway, planar cell polarity pathway
2306472
45
1:45
MEAFLGSRSGLWAGGPAPGQFYRIPSTPDSFMDPASALYRGPITR
PSQ01177
FD00068
Proteasome subunit beta type-6
P28072
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
33
cadherin binding, endopeptidase activity, threonine-type endopeptidase activity
240
Macropain delta chain, Multicatalytic endopeptidase complex delta chain, Proteasome delta chain, Proteasome subunit Y
PSMB6
9606
cytoplasm, cytosol, extracellular exosome, nucleoplasm, nucleus, proteasome complex, proteasome core complex, proteasome core complex, beta-subunit complex
anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, Fc-epsilon receptor signaling pathway, interleukin-1-mediated signaling pathway, MAPK cascade, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, NIK/NF-kappaB signaling, positive regulation of canonical Wnt signaling pathway, post-translational protein modification, pre-replicative complex assembly, proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, protein deubiquitination, protein polyubiquitination, regulation of cellular amino acid metabolic process, regulation of hematopoietic stem cell differentiation, regulation of mitotic cell cycle phase transition, regulation of mRNA stability, regulation of transcription from RNA polymerase II promoter in response to hypoxia, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, stimulatory C-type lectin receptor signaling pathway, T cell receptor signaling pathway, transmembrane transport, tumor necrosis factor-mediated signaling pathway, viral process, Wnt signaling pathway, planar cell polarity pathway
1888762, 2306472
33
2:34
AATLLAARGAGPAPAWGPEAFTPDWESREVSTG
PSQ01178
FD00068
Proteasome subunit beta type-6
P28073
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Rattus
Rattus norvegicus (Rat)
32
endopeptidase activity, threonine-type endopeptidase activity
240
Macropain delta chain, Multicatalytic endopeptidase complex delta chain, Proteasome chain 5, Proteasome delta chain, Proteasome subunit Y
Psmb6
10116
cytoplasm, nucleus, proteasome complex, proteasome core complex, proteasome core complex, beta-subunit complex
proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process
2335214
32
2:33
AAALAVRGAVSAPAFGPEALTPDWENREVSTG
PSQ01179
FD00101
Proteasome subunit beta type-5
P28074
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
59
endopeptidase activity, peptidase activity, threonine-type endopeptidase activity
263
Macropain epsilon chain, Multicatalytic endopeptidase complex epsilon chain, Proteasome chain 6, Proteasome epsilon chain, Proteasome subunit MB1, Proteasome subunit X
PSMB5
9606
centrosome, cytoplasm, cytosol, extracellular exosome, nucleoplasm, nucleus, proteasome complex, proteasome core complex, proteasome core complex, beta-subunit complex
anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, Fc-epsilon receptor signaling pathway, interleukin-1-mediated signaling pathway, MAPK cascade, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, NIK/NF-kappaB signaling, positive regulation of canonical Wnt signaling pathway, post-translational protein modification, pre-replicative complex assembly, proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, protein deubiquitination, protein polyubiquitination, proteolysis, regulation of cellular amino acid metabolic process, regulation of hematopoietic stem cell differentiation, regulation of mitotic cell cycle phase transition, regulation of mRNA stability, regulation of transcription from RNA polymerase II promoter in response to hypoxia, response to oxidative stress, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, stimulatory C-type lectin receptor signaling pathway, T cell receptor signaling pathway, transmembrane transport, tumor necrosis factor-mediated signaling pathway, viral process, Wnt signaling pathway, planar cell polarity pathway
2306472
59
1:59
MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHG
PSQ01180
FD00101
Proteasome subunit beta type-5
P28075
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Rattus
Rattus norvegicus (Rat)
59
endopeptidase activity, peptidase activity, threonine-type endopeptidase activity
263
Macropain epsilon chain, Multicatalytic endopeptidase complex epsilon chain, Proteasome chain 6, Proteasome epsilon chain, Proteasome subunit X
Psmb5
10116
cytoplasm, nucleus, proteasome complex, proteasome core complex, proteasome core complex, beta-subunit complex
proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis, response to oxidative stress
2335214
59
1:59
MALASVLQRPMPVNQHGFFGLGGRADLLDLGPGSPGDGLSLAAPSWGVPEEPRIEMLHG
PSQ01181
FD00068
Proteasome subunit beta type-9
P28077
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Rattus
Rattus norvegicus (Rat)
20
endopeptidase activity, proteasome binding, threonine-type endopeptidase activity
219
Low molecular mass protein 2, Macropain chain 7, Multicatalytic endopeptidase complex chain 7, Proteasome chain 7, Proteasome subunit beta-1i, Really interesting new gene 12 protein
Psmb9
10116
cytoplasm, cytosol, nucleus, proteasome complex, proteasome core complex, proteasome core complex, beta-subunit complex, spermatoproteasome complex
antigen processing and presentation, cellular response to electrical stimulus, cellular response to interleukin-1, cellular response to virus, liver development, muscle atrophy, proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, regulation of cysteine-type endopeptidase activity, response to alkaloid, response to bacterium, response to benzene, response to drug, spleen development, thymus development
2335214
20
1:20
MLQAGAPTAGSFRTGEVHTG
PSQ01182
FD00011
Alkaline protease 1
P28296
Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Fumigati
Neosartorya fumigata (strain ATCC MYA-4609 , A1100) (Aspergillus fumigatus)
80
fibrinogen binding, IgE binding, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity
403
Aspergillopeptidase B, Aspergillus proteinase B, Elastase, Elastinolytic serine proteinase, Oryzin
alp1
330879
extracellular region, extracellular space
complement activation, elastin catabolic process, evasion of host immune response via regulation of host complement system, pathogenesis, protein catabolic process
10677362
80
22:101
PVQETRRAAQKIPGKYIVTFKPGTDTATIESHTLWATDLHKRNLERRDTTSGEPPVGIEKSYKIKDFAAYAGSFDDATIE
PSQ01183
FD00016
Alpha-defensin 2
P28309
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus
Mus musculus (Mouse)
39
None
93
Cryptdin-1, Defensin-related cryptdin-2
Defa2
10090
extracellular space
antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, cellular response to lipopolysaccharide, defense response to bacterium, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, innate immune response in mucosa, membrane disruption in other organism, response to drug
1500163, 1500431
39
20:58
DPIQNTDEETKTEEQSGEEDQAVSVSFGDREGASLQEES
PSQ01184
FD00016
Alpha-defensin 3
P28310
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus
Mus musculus (Mouse)
42
None
93
Defensin-related cryptdin-3
Defa3
10090
extracellular space
antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, cellular response to lipopolysaccharide, defense response to bacterium, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, innate immune response in mucosa, membrane disruption in other organism, response to drug
1500431
42
17:58
VQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEES
PSQ01185
FD00016
Alpha-defensin 5
P28312
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus
Mus musculus (Mouse)
39
None
93
Defensin-related cryptdin-5
Defa5
10090
extracellular space
antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, cellular response to lipopolysaccharide, defense response to bacterium, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, innate immune response in mucosa, membrane disruption in other organism
1500431
39
20:58
DPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEEL
PSQ01186
FD00150
Ribosome-inactivating protein
P28522
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida Liliopsida Poales Poaceae PACMAD clade Panicoideae Andropogonodae Andropogoneae Tripsacinae Zea
Zea mays (Maize)
25
rRNA N-glycosylase activity, toxin activity
301
rRNA N-glycosidase
None
4577
None
defense response, negative regulation of translation
1744135
25
162:186
MATLEEEEVKMQMQMPEAADLAAAA
PSQ01187
FD00072
Photosystem II reaction center protein K
P28642
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Fabales Fabaceae Papilionoideae 50 kb inversion clade NPAAA clade Hologalegina IRL clade Fabeae Pisum
Pisum sativum (Garden pea)
24
None
46
None
psbK
3888
chloroplast thylakoid membrane, integral component of membrane, photosystem II reaction center
photosynthesis
8262226, 9632665
24
1:24
MLNIFSLVCICINSALYSSSFFLG
PSQ01188
FD00414
Gingipain R1
P28784
Bacteria Bacteroidetes Bacteroidia Bacteroidales Porphyromonadaceae Porphyromonas
Porphyromonas gingivalis
203
calcium ion binding, calcium-dependent cysteine-type endopeptidase activity
991
Arg-gingipain, Gingipain 1, RGP-1
rgpA
837
extracellular region
pathogenesis, proteolysis
1527017, 7864651
203
25:227
QTELGRNPNVRLLESTQQSVTKVQFRMDNLKFTEVQTPKGMAQVPTYTEGVNLSEKGMPTLPILSRSLAVSDTREMKVEVVSSKFIEKKNVLIAPSKGMIMRNEDPKKIPYVYGKSYSQNKFFPGEIATLDDPFILRDVRGQVVNFAPLQYNPVTKTLRIYTEITVAVSETSEQGKNILNKKGTFAGFEDTYKRMFMNYEPGR
PSQ01189
FD00118
Alpha-2-antiplasmin
P28800
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Bovinae Bos
Bos taurus (Bovine)
18
protease binding, protein homodimerization activity, serine-type endopeptidase inhibitor activity
492
Alpha-2-plasmin inhibitor, Serpin F2
SERPINF2
9913
cell surface, extracellular space, fibrinogen complex
acute-phase response, blood vessel morphogenesis, collagen fibril organization, maintenance of blood vessel diameter homeostasis by renin-angiotensin, negative regulation of endopeptidase activity, negative regulation of fibrinolysis, negative regulation of plasminogen activation, positive regulation of cell differentiation, positive regulation of collagen biosynthetic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of JNK cascade, positive regulation of smooth muscle cell proliferation, positive regulation of stress fiber assembly, positive regulation of transcription by RNA polymerase II, positive regulation of transforming growth factor beta production
1385210
18
23:40
FSPVSTMEPLDLQLMDGQ
PSQ01190
FD00375
Meprin A subunit alpha
P28825
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus
Mus musculus (Mouse)
44
metalloendopeptidase activity, zinc ion binding
747
Endopeptidase-2, MEP-1
Mep1a
10090
membrane, meprin A complex
None
1374387, 1894622, 8615815
44
21:64
VSIKHLLNGSDHDTDVGEQKDIFEINLAAGLNLFQGDILLPRTR
PSQ01191
FD00006
Alpha-conotoxin SII
P28879
Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Neogastropoda Conoidea Conidae Conus Pionoconus
Conus striatus (Striated cone)
29
acetylcholine receptor inhibitor activity, toxin activity
72
None
None
6493
extracellular region, host cell postsynaptic membrane
pathogenesis
1390774
29
22:50
FPSDRASDGRDDEAKDERSDMHESDRNGR
PSQ01192
FD00080
Guanylin
P28902
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Rattus
Rattus norvegicus (Rat)
77
guanylate cyclase activator activity, guanylate cyclase regulator activity
120
Guanylate cyclase activator 2A
Guca2a
10116
extracellular region
None
1346555
77
24:100
VQDGDLSFPLESVKQLKHLREVQEPTLMSHKKFALRLPKPVAPELCSQSAFPEALRPLCEKPNAEEILQRLEAIAQD
PSQ01193
FD00388
Carboxypeptidase T
P29068
Bacteria Firmicutes Bacilli Bacillales Thermoactinomycetaceae Thermoactinomyces
Thermoactinomyces vulgaris
75
metallocarboxypeptidase activity, zinc ion binding
424
None
cpt
2026
None
None
6424730
75
24:98
FSQNIENPSIFDLGIKLYKIDGVSTKEQRSAIASTGAAIEEVGKDYVKVLATPSEAKQIKQKGFTATVDTSLTTQ
PSQ01194
FD00152
Proprotein convertase subtilisin
P29122
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
86
endopeptidase activity, heparin binding, nerve growth factor binding, serine-type endopeptidase activity
969
Paired basic amino acid cleaving enzyme 4, Subtilisin-like proprotein convertase 4, Subtilisin
PCSK6
9606
cell surface, collagen-containing extracellular matrix, endoplasmic reticulum, extracellular region, extracellular space, Golgi lumen, membrane, plasma membrane
cornification, glycoprotein metabolic process, nerve growth factor processing, nerve growth factor production, peptide hormone processing, protein processing, regulation of BMP signaling pathway, regulation of lipoprotein lipase activity, secretion by cell
9738469
86
64:149
PPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR
PSQ01195
FD00478
Metalloendoproteinase 1
P29136
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Fabales Fabaceae Papilionoideae 50 kb inversion clade NPAAA clade indigoferoid/millettioid clade Phaseoleae Glycine Glycine subgen Soja
Glycine max (Soybean) (Glycine hispida)
105
metalloendopeptidase activity, zinc ion binding
305
SMEP1
None
3847
extracellular matrix
collagen catabolic process, extracellular matrix organization
16668986
105
29:133
HGPYAWDGEATYKFTTYHPGQNYKGLSNVKNYFHHLGYIPNAPHFDDNFDDTLVSAIKTYQKNYNLNVTGKFDINTLKQIMTPRCGVPDIIINTNKTTSFGMISD
PSQ01196
FD00248
Minor extracellular protease vpr
P29141
Bacteria Firmicutes Bacilli Bacillales Bacillaceae Bacillus
Bacillus subtilis (strain 168)
132
serine-type endopeptidase activity
806
None
vpr
224308
extracellular region
None
10658653, 1938892
132
29:160
APASSKTSADLEKAEVFGDIDMTTSKKTTVIVELKEKSLAEAKEAGESQSKSKLKTARTKAKNKAIKAVKNGKVNREYEQVFSGFSMKLPANEIPKLLAVKDVKAVYPNVTYKTDNMKDKDVTISEDAVSPQ
PSQ01197
FD00049
Bacillolysin
P29148
Bacteria Firmicutes Bacilli Bacillales Paenibacillaceae Paenibacillus
Paenibacillus polymyxa (Bacillus polymyxa)
262
metal ion binding, metalloendopeptidase activity
590
Neutral protease
npr
1406
extracellular region
None
1834632
262
25:286
ESSVSGPAQLTPTFHTEQWKAPSSVSGDDIVWSYLNRQKKSLLGVDSSSVREQFRIVDRTSDKSGVSHYRLKQYVNGIPVYGAEQTIHVGKSGEVTSYLGAVINEDQQEEATQGTTPKISASEAVYTAYKEAAARIEALPTSDDTISKDAEEPSSVSKDTYAEAANNDKTLSVDKDELSLDKASVLKDSKIEAVEAEKSSIAKIANLQPEVDPKAELYYYPKGDDLLLVYVTEVNVLEPAPLRTRYIIDANDGSIVFQYDII
PSQ01198
FD00146
Delta-ctenitoxin-Pn2a
P29425
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Lycosoidea Ctenidae Phoneutria
Phoneutria nigriventer (Brazilian armed spider) (Ctenus nigriventer)
17
toxin activity
82
Delta-CNTX-Pn1c , Neurotoxin Tx2-6
None
6918
extracellular region
None
1397265, 16278100, 19231838
17
18:34
ESIEESRDDFAVEELGR
PSQ01199
FD00074
Bacteriocin pediocin PA-1
P29430
Bacteria Firmicutes Bacilli Lactobacillales Lactobacillaceae Pediococcus Pediococcus acidilactici group
Pediococcus acidilactici
18
None
62
Pediocin ACH
pedA
1254
extracellular region
cytolysis, defense response to bacterium
1402795, 1575516
18
1:18
MKKIEKLTEKEMANIIGG
PSQ01200
FD00207
Glucan 1
P29717
Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Debaryomycetaceae Candida/Lodderomyces clade Candida
Candida albicans (strain SC5314
17
beta-glucosidase activity, cell adhesion molecule binding, glucan exo-1,3-beta-glucosidase activity, transferase activity
438
Exo-1
XOG1
237561
cell surface, cell wall, extracellular region, extracellular vesicle
cell-substrate adhesion, cellular glucan metabolic process, fungal-type cell wall organization, glucan catabolic process, pathogenesis, single-species biofilm formation in or on host organism, single-species biofilm formation on inanimate substrate
1789004, 8436950
17
22:38
SVISNPFKPNGNLKFKR