All Protein

Proseq ID	Family	Protein Name	Uniprot ID	Taxonomy	Organism	Prosequence length	Functions	Preproprotein length	Alter Name	Gene Name	NCBI ID	Cell Org	Process	PubMed	Total Proseq length	Proseq Loc	Prosequence Sequence
PSQ01301	FD00345	Stanniocalcin	P43648	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Protacanthopterygii Salmoniformes Salmonidae Salmoninae Oncorhynchus	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	15	hormone activity	256	Corpuscles of Stannius protein, Hypocalcin, Teleocalcin	stc	8022	extracellular space, multivesicular body, nucleus, yolk plasma	calcium ion homeostasis, calcium ion transport, response to calcium ion, response to inorganic substance, response to peptide hormone	3360288	15	19:33	TFDTDPEEASPRRAR
PSQ01302	FD00039	Collagenase 3	P45452	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo	Homo sapiens (Human)	84	calcium ion binding, collagen binding, endopeptidase activity, metalloendopeptidase activity, zinc ion binding	478	Matrix metalloproteinase-13	MMP13	9606	extracellular matrix, extracellular region, extracellular space	bone morphogenesis, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, proteolysis, response to amyloid-beta	8576151	84	20:103	LPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGE
PSQ01303	FND00173	Competence pheromone	P45453	Bacteria Firmicutes Bacilli Bacillales Bacillaceae Bacillus	Bacillus subtilis (strain 168)	45	pheromone activity	60	None	comX	224308	extracellular region	establishment of competence for transformation, sporulation resulting in formation of a cellular spore	8168130	45	1:45	MQDLINYFLNYPEALKKLKNKEACLIGFDVQETETIIKAYNDYYL
PSQ01304	FD00196	Type II secretion system protein K	P45781	Bacteria Proteobacteria Gammaproteobacteria Vibrionales Vibrionaceae Vibrio	Vibrio cholerae serotype O1 (strain ATCC 39315	7	None	336	Cholera toxin secretion protein EpsK, General secretion pathway protein K	epsK	243277	integral component of membrane, plasma membrane	protein secretion	10952301	7	1:7	MRAKQRG
PSQ01305	FD00350	Type IV pilus subunit protein TapA	P45791	Bacteria Proteobacteria Gammaproteobacteria Aeromonadales Aeromonadaceae Aeromonas	Aeromonas hydrophila	6	None	142	None	tapA	644	integral component of membrane	None	9344785	6	1:6	MKKQSG
PSQ01306	FD00504	Extracellular metalloproteinase mep	P46075	Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Fumigati	Neosartorya fumigata (strain ATCC MYA-4609 , A1100) (Aspergillus fumigatus)	227	metalloendopeptidase activity, zinc ion binding	634	AfuMep , Allergen Asp f 5 , Elastinolytic metalloproteinase mep, Fungalysin mep	mep	330879	extracellular space	pathogenesis	8188335	227	19:245	HPAHQSYGLNRRTVDLNAFRLKSLAKYVNATETVIEAPSSFAPFKPQSYVEVATQHVKMIAPDATFRVVDDHYVGDNGVAHVHFRQTANGLDIDNADFNVNVGKDGKVFSYGNSFYTGQIPSSAALTKRDFSDPVTALKGTTNTLQLPITVDSASSESTEEKESYVFKGVSGTVSDPKAKLVYFVKDDGTLALAWRVETDIDSNWLLTYIDAKSGEEIHGVVDYVAE
PSQ01307	FD00589	Neutral protease 2	P46076	Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Circumdati	Aspergillus oryzae (strain ATCC 42149	156	metal ion binding, metalloendopeptidase activity	359	Deuterolysin, Neutral protease II	None	510516	extracellular region	None	1886621, 8086433	156	20:175	APTAGSSSPGLEVKLTQIDNTRVKAVVKNTGSEEVSFVHLNFFKDAGPVKKVSIYRGQDEVQFEGIKRRLRSSGITKEAVTSLGAGETLEDEFDIASTSDLASGGPVSIRSHGFVPIVVDGKITGYIPYKSNDLTVNVDGGKAAKVTKALSQLTRR
PSQ01308	FD00574	Hemagglutinin components HA-70 type C	P46085	Viruses Duplodnaviria Heunggongvirae Uroviricota Caudoviricetes Caudovirales Siphoviridae	Clostridium botulinum C phage (Clostridium botulinum C bacteriophage)	6	None	623	HA3, Hemagglutinin components HA-22, Hemagglutinin components HA-22	HA-70	12336	extracellular region	pathogenesis	7802661	6	1:6	MSLSIK
PSQ01309	FND00040	Gallinacin-1	P46156	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Archelosauria Archosauria Dinosauria Saurischia Theropoda Coelurosauria Aves Neognathae Galloanserae Galliformes Phasianidae Phasianinae Gallus	Gallus gallus (Chicken)	6	CCR6 chemokine receptor binding, chemoattractant activity	65	Beta-defensin 1	GAL1	9031	extracellular space, secretory granule	cell chemotaxis, defense response, defense response to bacterium, defense response to fungus, killing of cells of other organism	8150085	6	20:25	GSSQAL
PSQ01310	FND00040	Gallinacin-1 alpha	P46157	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Archelosauria Archosauria Dinosauria Saurischia Theropoda Coelurosauria Aves Neognathae Galloanserae Galliformes Phasianidae Phasianinae Gallus	Gallus gallus (Chicken)	6	CCR6 chemokine receptor binding, chemoattractant activity	65	Antimicrobial peptide CHP2, Chicken heterophil peptide 2	None	9031	extracellular space, secretory granule	cell chemotaxis, defense response, defense response to bacterium, defense response to fungus, killing of cells of other organism	7964174, 8150085	6	20:25	GSSQAL
PSQ01311	FND00356	Gallinacin-2	P46158	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Archelosauria Archosauria Dinosauria Saurischia Theropoda Coelurosauria Aves Neognathae Galloanserae Galliformes Phasianidae Phasianinae Gallus	Gallus gallus (Chicken)	6	CCR6 chemokine receptor binding, chemoattractant activity	64	Beta-defensin 2	GAL2	9031	extracellular space, secretory granule	cell chemotaxis, defense response, defense response to bacterium	19151352, 8150085	6	23:28	SPRRDM
PSQ01312	FND00155	Cell wall mannoprotein CIS3	P47001	Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces	Saccharomyces cerevisiae (strain ATCC 204508	43	structural constituent of cell wall	227	Covalently-linked cell wall protein 5, Protein with internal repeats 4, Soluble cell wall protein 8	CIS3	559292	cell periphery, cellular bud tip, endoplasmic reticulum, extracellular region, fungal-type cell wall, fungal-type vacuole, plasma membrane	fungal-type cell wall organization	10438739, 12776183, 12898712, 16495216, 9301021, 9748433	43	22:64	EGYTPGEPWSTLTPTGSISCGAAEYTTTFGIAVQAITSSKAKR
PSQ01313	FD00372	SPS-sensor serine protease component SSY5	P47002	Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces	Saccharomyces cerevisiae (strain ATCC 204508	381	serine-type endopeptidase activity	699	Endoprotease SSY5	SSY5	559292	extrinsic component of plasma membrane	protein autoprocessing, protein processing, response to amino acid	16524914	381	1:381	MVRFFGLNKKKNEEKENTDLPADNEQNAAETSSSNVSGNEERIDPNSHDTNPENANNDDASTTFGSSIQSSSIFSRGRMTYGTGASSSMATSEMRSHSSGHSGSKNSKNLQGFKDVGKPLRAVSFLSPVKEEESQDTQNTLDVSSSTSSTLATSENARENSFTSRRSITLEYIHKSLSELEENLVDIMDDIHQDVISISKAVIEAIEYFKEFLPTTRDRIPYRISLEKSSSLRKINKIVLHFLDNLLVSDAFSNSRSILLRRFYFFLKKLNLITDDDLISESGVLPCLSVFCIGSHCNLPSMDKLGMILDELTKMDSSIISDQEGAFIAPILRGITPKSSILTIMFGLPNLQHEHYEMIKVLYSLFPDVHMYCVKDYIKKA
PSQ01314	FD00194	Carboxypeptidase A2	P48052	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo	Homo sapiens (Human)	96	carboxypeptidase activity, metallocarboxypeptidase activity, zinc ion binding	420	None	CPA2	9606	extracellular region, extracellular space, vacuole	protein catabolic process in the vacuole, proteolysis	8318831	96	19:114	LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRER
PSQ01315	FD00094	Photosystem II CP43 reaction center protein	P48187	Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida Liliopsida Poales Poaceae PACMAD clade Panicoideae Andropogonodae Andropogoneae Tripsacinae Zea	Zea mays (Maize)	14	chlorophyll binding, electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity, metal ion binding	480	PSII 43 kDa protein , Protein CP-43	psbC	4577	chloroplast thylakoid membrane, integral component of membrane, photosystem II	photosynthetic electron transport in photosystem II, protein-chromophore linkage	22833285	14	1:14	MKILYSLRRFYHVE
PSQ01316	FD00253	Cytochrome b-c1 complex subunit 8	P48503	Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Sordariomycetes Sordariomycetidae Sordariales Sordariaceae Neurospora	Neurospora crassa (strain ATCC 24698 , FGSC 987)	8	ubiquinol-cytochrome-c reductase activity	107	Complex III subunit 8, Complex III subunit VIII , Ubiquinol-cytochrome c reductase complex 11 kDa protein, Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C	qcr8	367110	integral component of membrane, mitochondrial respiratory chain complex III	mitochondrial electron transport, ubiquinol to cytochrome c	9003361	8	1:8	MRPTQTML
PSQ01317	FD00525	Endochitinase 42	P48827	Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Sordariomycetes Hypocreomycetidae Hypocreales Hypocreaceae Trichoderma	Trichoderma harzianum (Hypocrea lixii)	12	chitin binding, chitinase activity	423	42 kDa endochitinase, Chitinase 42	chit42	5544	extracellular region	chitin catabolic process, polysaccharide catabolic process	7750151	12	23:34	KPGHRRASVEKR
PSQ01318	FD00423	Dextranase	P48845	Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Trichocomaceae Talaromyces Talaromyces sect Trachyspermi	Talaromyces minioluteus (Filamentous fungus) (Penicillium minioluteum)	15	dextranase activity	608	Alpha-1	DEX	28574	extracellular region	metabolic process	8905923	15	20:34	GAVMHPPGNSHPGTH
PSQ01319	FD00027	Ligninase LG2	P49012	Eukaryota Fungi Dikarya Basidiomycota Agaricomycotina Agaricomycetes Polyporales Phanerochaetaceae Phanerochaete	Phanerochaete chrysosporium (White-rot fungus) (Sporotrichum pruinosum)	7	diarylpropane peroxidase activity, heme binding, metal ion binding	371	Diarylpropane peroxidase, Lignin peroxidase	GLG2	5306	None	lignin catabolic process, response to oxidative stress	1743510	7	22:28	AVVKEKR
PSQ01320	FD00107	Legumain	P49046	Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Fabales Fabaceae Papilionoideae 50 kb inversion clade NPAAA clade indigoferoid/millettioid clade Phaseoleae Canavalia	Canavalia ensiformis (Jack bean) (Dolichos ensiformis)	20	cysteine-type endopeptidase activity	480	Asparaginyl endopeptidase	None	3823	None	proteolysis involved in cellular protein catabolic process	8429028	20	16:35	RLNRREWDSVIQLPTEPVDD
PSQ01321	FD00243	Beta-diguetoxin-Dc1a	P49126	Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Haplogynae Pholcoidea Diguetidae Diguetia	Diguetia canities (Desert bush spider) (Segestria canities)	21	toxin activity	94	Insecticidal toxin DTX9	None	38407	extracellular region	None	8541888	21	18:38	LEERLDKDADIMLDSPADMER
PSQ01322	FD00007	Mite allergen Der f 3	P49275	Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Acari Acariformes Sarcoptiformes Astigmata Psoroptidia Analgoidea Pyroglyphidae Dermatophagoidinae Dermatophagoides	Dermatophagoides farinae (American house dust mite)	11	serine-type endopeptidase activity	259	Allergen Der f III	DERF3	6954	extracellular region	None	2732406	11	17:27	TPILPSSPNAT
PSQ01323	FD00007	Mite allergen Der f 6	P49276	Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Acari Acariformes Sarcoptiformes Astigmata Psoroptidia Analgoidea Pyroglyphidae Dermatophagoidinae Dermatophagoides	Dermatophagoides farinae (American house dust mite)	30	serine-type endopeptidase activity	279	Allergen Der f VI, DF5	DERF6	6954	extracellular region	None	8334537	30	20:49	RFPRSLQPKWAYLDSNEFPRSKIGDSPIAG
PSQ01324	FD00076	Phospholipase A1	P49369	Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Hymenoptera Apocrita Aculeata Vespoidea Vespidae Vespinae Vespula	Vespula vulgaris (Yellow jacket) (Wasp)	9	1-acyl-2-lysophosphatidylserine acylhydrolase activity, phosphatidylserine 1-acylhydrolase activity, phospholipase A1 activity, phospholipase A2 activity, phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine), phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine), triglyceride lipase activity	336	Allergen Ves v I	None	7454	extracellular region	lipid catabolic process	8828537	9	28:36	DPLSYELDR
PSQ01325	FD00481	Caspase-4	P49662	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo	Homo sapiens (Human)	19	CARD domain binding, cysteine-type endopeptidase activity, cysteine-type endopeptidase activity involved in apoptotic signaling pathway	377	ICE and Ced-3 homolog 2 , ICE(rel)-II , Mih1 , Protease TX	CASP4	9606	AIM2 inflammasome complex, cytoplasm, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, extracellular region, IPAF inflammasome complex, mitochondrion, NLRP3 inflammasome complex, plasma membrane, protein-containing complex	apoptotic process, cellular response to amyloid-beta, execution phase of apoptosis, inflammatory response, innate immune response, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, positive regulation of tumor necrosis factor-mediated signaling pathway, protein autoprocessing, proteolysis, pyroptosis, regulation of apoptotic process, regulation of inflammatory response	7797510	19	271:289	SPASLEVASSQSSENLEED
PSQ01326	FD00129	Vascular endothelial growth factor C	P49767	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo	Homo sapiens (Human)	80	chemoattractant activity, growth factor activity, vascular endothelial growth factor receptor 3 binding, vascular endothelial growth factor receptor binding	420	Flt4 ligand, Vascular endothelial growth factor-related protein	VEGFC	9606	extracellular region, extracellular space, membrane, platelet alpha granule lumen	animal organ morphogenesis, cellular response to leukemia inhibitory factor, induction of positive chemotaxis, morphogenesis of embryonic epithelium, negative regulation of blood pressure, negative regulation of osteoblast differentiation, platelet degranulation, positive regulation of angiogenesis, positive regulation of blood vessel endothelial cell migration, positive regulation of cell division, positive regulation of cell population proliferation, positive regulation of endothelial cell proliferation, positive regulation of lymphangiogenesis, positive regulation of mast cell chemotaxis, positive regulation of mesenchymal stem cell proliferation, positive regulation of neuroblast proliferation, positive regulation of protein autophosphorylation, positive regulation of protein kinase activity, positive regulation of protein phosphorylation, positive regulation of protein secretion, regulation of vascular endothelial growth factor receptor signaling pathway, response to drug, response to hypoxia, signal transduction, sprouting angiogenesis, substrate-dependent cell migration, vascular endothelial growth factor receptor signaling pathway, vascular endothelial growth factor signaling pathway	9233800	80	32:111	FESGLDLSDAEPDAGEATAYASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSRTEETIKFAA
PSQ01327	FD00550	Cathelicidin antimicrobial peptide	P49913	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo	Homo sapiens (Human)	101	lipopolysaccharide binding	170	18 kDa cationic antimicrobial protein	CAMP	9606	extracellular exosome, extracellular region, extracellular space, specific granule, specific granule lumen, tertiary granule lumen	antibacterial humoral response, antifungal humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, antimicrobial humoral response, chronic inflammatory response, cytolysis by host of symbiont cells, defense response to bacterium, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, innate immune response, innate immune response in mucosa, killing by host of symbiont cells, modulation of process of other organism, neutrophil degranulation, positive regulation of interleukin-8 production, response to yeast	7615076	101	31:131	QVLSYKEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARGSFDISCDKDNKR
PSQ01328	FD00301	Adenylate kinase	P49983	Eukaryota Metamonada Parabasalia Trichomonadida Trichomonadidae Trichomonas	Trichomonas vaginalis	9	adenylate kinase activity, ATP binding	229	ATP-AMP transphosphorylase, ATP, Adenylate monophosphate kinase	None	5722	hydrogenosome	None	7808479	9	1:9	MLSTLAKRF
PSQ01329	FD00587	Matrix metalloproteinase-14	P50281	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo	Homo sapiens (Human)	91	endopeptidase activity, integrin binding, metalloaminopeptidase activity, metalloendopeptidase activity, zinc ion binding	582	MMP-X1, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase	MMP14	9606	cytoplasmic vesicle, cytosol, extracellular matrix, extracellular space, focal adhesion, Golgi lumen, integral component of plasma membrane, intermediate filament cytoskeleton, macropinosome, melanosome, nucleus, plasma membrane	angiogenesis, astrocyte cell migration, branching morphogenesis of an epithelial tube, cell motility, chondrocyte proliferation, collagen catabolic process, craniofacial suture morphogenesis, embryonic cranial skeleton morphogenesis, endochondral ossification, endodermal cell differentiation, endothelial cell proliferation, extracellular matrix disassembly, extracellular matrix organization, head development, lung development, male gonad development, negative regulation of focal adhesion assembly, negative regulation of Notch signaling pathway, ovarian follicle development, positive regulation of B cell differentiation, positive regulation of cell growth, positive regulation of cell migration, positive regulation of macrophage migration, positive regulation of myotube differentiation, positive regulation of protein processing, protein processing, proteolysis, regulation of protein localization to plasma membrane, response to estrogen, response to hypoxia, response to mechanical stimulus, response to odorant, response to organic cyclic compound, response to oxidative stress, skeletal system development, tissue remodeling, zymogen activation	8804434	91	21:111	ALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKR
PSQ01330	FD00306	Exoglucanase B	P50899	Bacteria Actinobacteria Micrococcales Cellulomonadaceae Cellulomonas	Cellulomonas fimi (strain ATCC 484 , NCIMB 8980	20	cellulase activity, cellulose 1,4-beta-cellobiosidase activity, polysaccharide binding	1090	1, CBP120, Exocellobiohydrolase B	cbhB	590998	None	cellulose catabolic process	8147863, 8458833	20	34:53	AAGAGQPATVTVPAASPVRA
PSQ01331	FD00006	Alpha-conotoxin EI	P50982	Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Neogastropoda Conoidea Conidae Conus Chelyconus	Conus ermineus (Atlantic fish-hunting cone)	27	acetylcholine receptor inhibitor activity, toxin activity	62	None	None	55423	extracellular region, host cell postsynaptic membrane	modulation of receptor activity in other organism, pathogenesis	7578057	27	17:43	FTLDRASDGRDAAANDKASDLIALTAR
PSQ01332	FD00006	Alpha-conotoxin PnIB	P50985	Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Neogastropoda Conoidea Conidae Conus Darioconus	Conus pennaceus (Feathered cone) (Conus episcopus)	23	acetylcholine receptor inhibitor activity, toxin activity	61	None	None	37335	extracellular region, host cell postsynaptic membrane	pathogenesis	8068627	23	22:44	FTSDRASDDGNAAASDLIALTIK
PSQ01333	FD00007	Trypsin	P51588	Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Diptera Brachycera Muscomorpha Oestroidea Sarcophagidae Sarcophaga Neobellieria	Sarcophaga bullata (Grey flesh fly) (Neobellieria bullata)	10	serine-type endopeptidase activity	254	None	None	7385	extracellular space	digestion	8620885	10	17:26	GTLPNDLDGR
PSQ01334	FD00480	Metallo-beta-lactamase L1 type 3	P52700	Bacteria Proteobacteria Gammaproteobacteria Xanthomonadales Xanthomonadaceae Stenotrophomonas Stenotrophomonas maltophilia group	Stenotrophomonas maltophilia (Pseudomonas maltophilia) (Xanthomonas, maltophilia)	12	beta-lactamase activity, zinc ion binding	290	B3 metallo-beta-lactamase , Beta-lactamase type III , Metallo-beta-lactamase L1 type III , Penicillinase	None	40324	periplasmic space	antibiotic catabolic process, response to antibiotic	3931629	12	22:33	AEVPLPQLRAYT
PSQ01335	FD00407	Carboxypeptidase Y	P52710	Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Phaffomycetaceae Komagataella	Komagataella phaffii (strain GS115	87	serine-type carboxypeptidase activity	523	Carboxypeptidase YSCY	PRC1	644223	extracellular region, fungal-type vacuole lumen	macroautophagy, phytochelatin biosynthetic process, zymogen activation	8789258	87	21:107	LSLQMPMALEASYASLVEKATLAVGQEIDAIQKGIQQGWLEVETRFPTIVSQLSYSTGPKFAIKKKDATFWDFYVESQELPNYRLRV
PSQ01336	FD00162	Serine-type carboxypeptidase F	P52718	Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Circumdati	Aspergillus niger	27	serine-type carboxypeptidase activity	538	CPD-II	pepF	5061	None	None	1637154	27	26:52	HGRFGQKARDAMNIAKRSANAVKHSLK
PSQ01337	FD00393	Probable alcohol acetyltransferase	P53219	Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces	Saccharomyces cerevisiae (strain ATCC 204508	8	hydrolase activity, transferase activity	342	Intermediate cleaved by mitochondrial octapeptidyl aminopeptidase protein 32	IMO32	559292	mitochondrion	None	21525245	8	39:46	FHSLAKVL
PSQ01338	FD00166	Probable family 17 glucosidase SCW4	P53334	Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces	Saccharomyces cerevisiae (strain ATCC 204508	11	1,3-beta-glucanosyltransferase activity, glucan endo-1,3-beta-D-glucosidase activity, glucosidase activity, mRNA binding	386	Soluble cell wall protein 4	SCW4	559292	cell surface, extracellular region, fungal-type cell wall, fungal-type vacuole, vacuole	carbohydrate metabolic process, cell wall organization, conjugation with cellular fusion	9748433	11	20:30	APANHEHKDKR
PSQ01339	FD00499	Dipeptidyl peptidase 1	P53634	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo	Homo sapiens (Human)	96	chaperone binding, chloride ion binding, cysteine-type endopeptidase activity, cysteine-type peptidase activity, dipeptidyl-peptidase activity, identical protein binding, peptidase activator activity involved in apoptotic process, phosphatase binding, protein self-association, serine-type endopeptidase activity	463	Cathepsin C, Cathepsin J, Dipeptidyl peptidase I, Dipeptidyl transferase	CTSC	9606	azurophil granule lumen, centrosome, collagen-containing extracellular matrix, COPII-coated ER to Golgi transport vesicle, endoplasmic reticulum lumen, endoplasmic reticulum-Golgi intermediate compartment membrane, extracellular exosome, extracellular region, extracellular space, Golgi apparatus, intracellular membrane-bounded organelle, lysosome, membrane, nucleoplasm	aging, COPII vesicle coating, endoplasmic reticulum to Golgi vesicle-mediated transport, immune response, negative regulation of myelination, neutrophil degranulation, positive regulation of apoptotic signaling pathway, positive regulation of microglial cell activation, positive regulation of proteolysis involved in cellular protein catabolic process, proteolysis, proteolysis involved in cellular protein catabolic process, response to organic substance, T cell mediated cytotoxicity	1586157, 7665576, 9507095	96	135:230	ACFTGKKVGTASENVYVNIAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILH
PSQ01340	FD00580	Protein MoaF	P54796	Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Enterobacteriaceae Klebsiella	Klebsiella aerogenes (Enterobacter aerogenes)	13	None	262	None	moaF	548	None	None	7590328	13	1:13	MTSEAVFIQVGAL
PSQ01341	FD00120	Caspase-7	P55214	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Cricetidae Cricetinae Mesocricetus	Mesocricetus auratus (Golden hamster)	22	cysteine-type endopeptidase activity	303	Apoptotic protease Mch-3, ICE-like apoptotic protease 3, SREBP cleavage activity 2	CASP7	10036	cytoplasm	apoptotic process	8643593	22	2:23	ADDQNCAPELEKADPSGEDGVD
PSQ01342	FD00030	Aspergillopepsin-1	P55325	Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Circumdati	Aspergillus niger	49	aspartic-type endopeptidase activity	394	Aspartic protease pepA, Aspergillopepsin I, Aspergillopeptidase A, Proctase B	pepA	5061	extracellular region	None	7787314	49	21:69	APAPTRKGFTINQIARPANKTRTVNLPGLYARSLAKFGGTVPQSVKEAA
PSQ01343	FND00253	Lebocin-3	P55796	Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Lepidoptera Glossata Ditrysia Bombycoidea Bombycidae Bombycinae Bombyx	Bombyx mori (Silk moth)	104	None	180	None	LEB3	7091	extracellular region	defense response to bacterium, innate immune response	7654207	104	17:120	QASCQRFIQPTFRPPPTQRPITRTVRQAGQEPLWLYQGDNVPRAPSTADHPILPSKIDDVQLDPNRRYVRSVTNPENNEASIEHSHHTVDIGLDQPIESHRNTR
PSQ01344	FD00297	Small ubiquitin-related modifier 3	P55854	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo	Homo sapiens (Human)	11	protein tag, ubiquitin-like protein ligase binding	103	SMT3 homolog 1 , SUMO-2 , Ubiquitin-like protein SMT3A	SUMO3	9606	cytoplasm, kinetochore, nucleoplasm, nucleus, PML body	negative regulation of DNA binding, protein sumoylation, regulation of protein localization to nucleus	15487983, 16608850	11	93:103	VPESSLAGHSF
PSQ01345	FD00446	Gastrin	P55885	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Perissodactyla Equidae Equus	Equus caballus (Horse)	40	hormone activity	107	None	GAST	9796	extracellular space	G protein-coupled receptor signaling pathway, response to food	9716385	40	22:61	SWKPCSQLQDAPSGPGANKGLYPHWPDQLDRLGPASHHRR
PSQ01346	FD00294	Phospholipase D alpha 2	P55939	Reviewed 812 AA Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Brassiceae Brassica	Brassica oleracea var	36	calcium ion binding, N-acylphosphatidylethanolamine-specific phospholipase D activity, phospholipase D activity	812	Choline phosphatase 2, Phosphatidylcholine-hydrolyzing phospholipase D 2	PLD2	3716	cytoplasm, membrane	lipid catabolic process, phosphatidylcholine metabolic process	8353126	36	1:36	MAQHLLHGTLHATIYEVDALHTGGLRSAGFLGKIIS
PSQ01347	FD00085	Aspartic protease 3	P55956	Eukaryota Metazoa Ecdysozoa Nematoda Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis	Caenorhabditis elegans	38	aspartic-type endopeptidase activity	398	None	asp-3	6239	cytoplasm, extracellular region, lysosome	cell death, necrotic cell death, programmed cell death	9150941	38	18:55	IQRIKLEKRTYTREQYKFGSIQEHLKAKYVPGYIPNKD
PSQ01348	FD00033	Alpha-conotoxin PIVA	P55963	Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Neogastropoda Conoidea Conidae Conus Chelyconus	Conus purpurascens (Purple cone)	25	acetylcholine receptor inhibitor activity, toxin activity	68	Alpha-A-conotoxin PIVA	None	41690	extracellular region, host cell postsynaptic membrane	pathogenesis	7673220	25	17:41	FTSDRASDDRNTNDKASRLLSHVVR
PSQ01349	FD00168	Probable insulin-like peptide beta-type 5	P56174	Eukaryota Metazoa Ecdysozoa Nematoda Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis	Caenorhabditis elegans	39	hormone activity, insulin receptor binding	119	None	ins-6	6239	extracellular space	cellular response to salt, chemosensory behavior, dauer larval development, insulin receptor signaling pathway, negative regulation of dauer entry, olfactory learning, regulation of synaptic growth at neuromuscular junction	23665919	39	20:58	FRQSFGPSMSEESASMQLLRELQHNMMESAHRPMPRARR
PSQ01350	FD00002	Frenatin-3	P56249	Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Hylidae Pelodryadinae Nyctimystes	Nyctimystes infrafrenatus (White-lipped tree frog) (Litoria infrafrenata)	24	None	68	None	None	61195	extracellular region	defense response to bacterium, innate immune response	15996792, 9225251	24	23:46	EKEKREDQNEEEVDENEEESEEKR

Stanniocalcin

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Protacanthopterygii Salmoniformes Salmonidae Salmoninae Oncorhynchus

Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

15

hormone activity

256

Corpuscles of Stannius protein, Hypocalcin, Teleocalcin

stc

8022

extracellular space, multivesicular body, nucleus, yolk plasma

calcium ion homeostasis, calcium ion transport, response to calcium ion, response to inorganic substance, response to peptide hormone

3360288

15

19:33

TFDTDPEEASPRRAR

PSQ01302

FD00039

Collagenase 3

P45452

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Homo sapiens (Human)

84

calcium ion binding, collagen binding, endopeptidase activity, metalloendopeptidase activity, zinc ion binding

478

Matrix metalloproteinase-13

MMP13

9606

extracellular matrix, extracellular region, extracellular space

bone morphogenesis, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, proteolysis, response to amyloid-beta

8576151

84

20:103

LPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGE

PSQ01303

FND00173

Competence pheromone

P45453

Bacteria Firmicutes Bacilli Bacillales Bacillaceae Bacillus

Bacillus subtilis (strain 168)

45

pheromone activity

60

None

comX

224308

extracellular region

establishment of competence for transformation, sporulation resulting in formation of a cellular spore

8168130

45

1:45

MQDLINYFLNYPEALKKLKNKEACLIGFDVQETETIIKAYNDYYL

PSQ01304

FD00196

Type II secretion system protein K

P45781

Bacteria Proteobacteria Gammaproteobacteria Vibrionales Vibrionaceae Vibrio

Vibrio cholerae serotype O1 (strain ATCC 39315

7

None

336

Cholera toxin secretion protein EpsK, General secretion pathway protein K

epsK

243277

integral component of membrane, plasma membrane

protein secretion

10952301

7

1:7

MRAKQRG

PSQ01305

FD00350

Type IV pilus subunit protein TapA

P45791

Bacteria Proteobacteria Gammaproteobacteria Aeromonadales Aeromonadaceae Aeromonas

Aeromonas hydrophila

6

None

142

None

tapA

644

integral component of membrane

None

9344785

6

1:6

MKKQSG

PSQ01306

FD00504

Extracellular metalloproteinase mep

P46075

Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Fumigati

Neosartorya fumigata (strain ATCC MYA-4609 , A1100) (Aspergillus fumigatus)

227

metalloendopeptidase activity, zinc ion binding

634

AfuMep , Allergen Asp f 5 , Elastinolytic metalloproteinase mep, Fungalysin mep

mep

330879

extracellular space

pathogenesis

8188335

227

19:245

HPAHQSYGLNRRTVDLNAFRLKSLAKYVNATETVIEAPSSFAPFKPQSYVEVATQHVKMIAPDATFRVVDDHYVGDNGVAHVHFRQTANGLDIDNADFNVNVGKDGKVFSYGNSFYTGQIPSSAALTKRDFSDPVTALKGTTNTLQLPITVDSASSESTEEKESYVFKGVSGTVSDPKAKLVYFVKDDGTLALAWRVETDIDSNWLLTYIDAKSGEEIHGVVDYVAE

PSQ01307

FD00589

Neutral protease 2

P46076

Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Circumdati

Aspergillus oryzae (strain ATCC 42149

156

metal ion binding, metalloendopeptidase activity

359

Deuterolysin, Neutral protease II

None

510516

extracellular region

None

1886621, 8086433

156

20:175

APTAGSSSPGLEVKLTQIDNTRVKAVVKNTGSEEVSFVHLNFFKDAGPVKKVSIYRGQDEVQFEGIKRRLRSSGITKEAVTSLGAGETLEDEFDIASTSDLASGGPVSIRSHGFVPIVVDGKITGYIPYKSNDLTVNVDGGKAAKVTKALSQLTRR

PSQ01308

FD00574

Hemagglutinin components HA-70 type C

P46085

Viruses Duplodnaviria Heunggongvirae Uroviricota Caudoviricetes Caudovirales Siphoviridae

Clostridium botulinum C phage (Clostridium botulinum C bacteriophage)

6

None

623

HA3, Hemagglutinin components HA-22, Hemagglutinin components HA-22

HA-70

12336

extracellular region

pathogenesis

7802661

6

1:6

MSLSIK

PSQ01309

FND00040

Gallinacin-1

P46156

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Archelosauria Archosauria Dinosauria Saurischia Theropoda Coelurosauria Aves Neognathae Galloanserae Galliformes Phasianidae Phasianinae Gallus

Gallus gallus (Chicken)

6

CCR6 chemokine receptor binding, chemoattractant activity

65

Beta-defensin 1

GAL1

9031

extracellular space, secretory granule

cell chemotaxis, defense response, defense response to bacterium, defense response to fungus, killing of cells of other organism

8150085

6

20:25

GSSQAL

PSQ01310

FND00040

Gallinacin-1 alpha

P46157

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Archelosauria Archosauria Dinosauria Saurischia Theropoda Coelurosauria Aves Neognathae Galloanserae Galliformes Phasianidae Phasianinae Gallus

Gallus gallus (Chicken)

6

CCR6 chemokine receptor binding, chemoattractant activity

65

Antimicrobial peptide CHP2, Chicken heterophil peptide 2

None

9031

extracellular space, secretory granule

cell chemotaxis, defense response, defense response to bacterium, defense response to fungus, killing of cells of other organism

7964174, 8150085

6

20:25

GSSQAL

PSQ01311

FND00356

Gallinacin-2

P46158

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Archelosauria Archosauria Dinosauria Saurischia Theropoda Coelurosauria Aves Neognathae Galloanserae Galliformes Phasianidae Phasianinae Gallus

Gallus gallus (Chicken)

6

CCR6 chemokine receptor binding, chemoattractant activity

64

Beta-defensin 2

GAL2

9031

extracellular space, secretory granule

cell chemotaxis, defense response, defense response to bacterium

19151352, 8150085

6

23:28

SPRRDM

PSQ01312

FND00155

Cell wall mannoprotein CIS3

P47001

Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces

Saccharomyces cerevisiae (strain ATCC 204508

43

structural constituent of cell wall

227

Covalently-linked cell wall protein 5, Protein with internal repeats 4, Soluble cell wall protein 8

CIS3

559292

cell periphery, cellular bud tip, endoplasmic reticulum, extracellular region, fungal-type cell wall, fungal-type vacuole, plasma membrane

fungal-type cell wall organization

10438739, 12776183, 12898712, 16495216, 9301021, 9748433

43

22:64

EGYTPGEPWSTLTPTGSISCGAAEYTTTFGIAVQAITSSKAKR

PSQ01313

FD00372

SPS-sensor serine protease component SSY5

P47002

Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces

Saccharomyces cerevisiae (strain ATCC 204508

381

serine-type endopeptidase activity

699

Endoprotease SSY5

SSY5

559292

extrinsic component of plasma membrane

protein autoprocessing, protein processing, response to amino acid

16524914

381

1:381

MVRFFGLNKKKNEEKENTDLPADNEQNAAETSSSNVSGNEERIDPNSHDTNPENANNDDASTTFGSSIQSSSIFSRGRMTYGTGASSSMATSEMRSHSSGHSGSKNSKNLQGFKDVGKPLRAVSFLSPVKEEESQDTQNTLDVSSSTSSTLATSENARENSFTSRRSITLEYIHKSLSELEENLVDIMDDIHQDVISISKAVIEAIEYFKEFLPTTRDRIPYRISLEKSSSLRKINKIVLHFLDNLLVSDAFSNSRSILLRRFYFFLKKLNLITDDDLISESGVLPCLSVFCIGSHCNLPSMDKLGMILDELTKMDSSIISDQEGAFIAPILRGITPKSSILTIMFGLPNLQHEHYEMIKVLYSLFPDVHMYCVKDYIKKA

PSQ01314

FD00194

Carboxypeptidase A2

P48052

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Homo sapiens (Human)

96

carboxypeptidase activity, metallocarboxypeptidase activity, zinc ion binding

420

None

CPA2

9606

extracellular region, extracellular space, vacuole

protein catabolic process in the vacuole, proteolysis

8318831

96

19:114

LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRER

PSQ01315

FD00094

Photosystem II CP43 reaction center protein

P48187

Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida Liliopsida Poales Poaceae PACMAD clade Panicoideae Andropogonodae Andropogoneae Tripsacinae Zea

Zea mays (Maize)

14

chlorophyll binding, electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity, metal ion binding

480

PSII 43 kDa protein , Protein CP-43

psbC

4577

chloroplast thylakoid membrane, integral component of membrane, photosystem II

photosynthetic electron transport in photosystem II, protein-chromophore linkage

22833285

14

1:14

MKILYSLRRFYHVE

PSQ01316

FD00253

Cytochrome b-c1 complex subunit 8

P48503

Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Sordariomycetes Sordariomycetidae Sordariales Sordariaceae Neurospora

Neurospora crassa (strain ATCC 24698 , FGSC 987)

8

ubiquinol-cytochrome-c reductase activity

107

Complex III subunit 8, Complex III subunit VIII , Ubiquinol-cytochrome c reductase complex 11 kDa protein, Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C

qcr8

367110

integral component of membrane, mitochondrial respiratory chain complex III

mitochondrial electron transport, ubiquinol to cytochrome c

9003361

8

1:8

MRPTQTML

PSQ01317

FD00525

Endochitinase 42

P48827

Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Sordariomycetes Hypocreomycetidae Hypocreales Hypocreaceae Trichoderma

Trichoderma harzianum (Hypocrea lixii)

12

chitin binding, chitinase activity

423

42 kDa endochitinase, Chitinase 42

chit42

5544

extracellular region

chitin catabolic process, polysaccharide catabolic process

7750151

12

23:34

KPGHRRASVEKR

PSQ01318

FD00423

Dextranase

P48845

Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Trichocomaceae Talaromyces Talaromyces sect Trachyspermi

Talaromyces minioluteus (Filamentous fungus) (Penicillium minioluteum)

15

dextranase activity

608

Alpha-1

DEX

28574

extracellular region

metabolic process

8905923

15

20:34

GAVMHPPGNSHPGTH

PSQ01319

FD00027

Ligninase LG2

P49012

Eukaryota Fungi Dikarya Basidiomycota Agaricomycotina Agaricomycetes Polyporales Phanerochaetaceae Phanerochaete

Phanerochaete chrysosporium (White-rot fungus) (Sporotrichum pruinosum)

7

diarylpropane peroxidase activity, heme binding, metal ion binding

371

Diarylpropane peroxidase, Lignin peroxidase

GLG2

5306

None

lignin catabolic process, response to oxidative stress

1743510

7

22:28

AVVKEKR

PSQ01320

FD00107

Legumain

P49046

Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Fabales Fabaceae Papilionoideae 50 kb inversion clade NPAAA clade indigoferoid/millettioid clade Phaseoleae Canavalia

Canavalia ensiformis (Jack bean) (Dolichos ensiformis)

20

cysteine-type endopeptidase activity

480

Asparaginyl endopeptidase

None

3823

None

proteolysis involved in cellular protein catabolic process

8429028

20

16:35

RLNRREWDSVIQLPTEPVDD

PSQ01321

FD00243

Beta-diguetoxin-Dc1a

P49126

Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Haplogynae Pholcoidea Diguetidae Diguetia

Diguetia canities (Desert bush spider) (Segestria canities)

21

toxin activity

94

Insecticidal toxin DTX9

None

38407

extracellular region

None

8541888

21

18:38

LEERLDKDADIMLDSPADMER

PSQ01322

FD00007

Mite allergen Der f 3

P49275

Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Acari Acariformes Sarcoptiformes Astigmata Psoroptidia Analgoidea Pyroglyphidae Dermatophagoidinae Dermatophagoides

Dermatophagoides farinae (American house dust mite)

11

serine-type endopeptidase activity

259

Allergen Der f III

DERF3

6954

extracellular region

None

2732406

11

17:27

TPILPSSPNAT

PSQ01323

FD00007

Mite allergen Der f 6

P49276

Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Acari Acariformes Sarcoptiformes Astigmata Psoroptidia Analgoidea Pyroglyphidae Dermatophagoidinae Dermatophagoides

Dermatophagoides farinae (American house dust mite)

30

serine-type endopeptidase activity

279

Allergen Der f VI, DF5

DERF6

6954

extracellular region

None

8334537

30

20:49

RFPRSLQPKWAYLDSNEFPRSKIGDSPIAG

PSQ01324

FD00076

Phospholipase A1

P49369

Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Hymenoptera Apocrita Aculeata Vespoidea Vespidae Vespinae Vespula

Vespula vulgaris (Yellow jacket) (Wasp)

9

1-acyl-2-lysophosphatidylserine acylhydrolase activity, phosphatidylserine 1-acylhydrolase activity, phospholipase A1 activity, phospholipase A2 activity, phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine), phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine), triglyceride lipase activity

336

Allergen Ves v I

None

7454

extracellular region

lipid catabolic process

8828537

9

28:36

DPLSYELDR

PSQ01325

FD00481

Caspase-4

P49662

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Homo sapiens (Human)

19

CARD domain binding, cysteine-type endopeptidase activity, cysteine-type endopeptidase activity involved in apoptotic signaling pathway

377

ICE and Ced-3 homolog 2 , ICE(rel)-II , Mih1 , Protease TX

CASP4

9606

AIM2 inflammasome complex, cytoplasm, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, extracellular region, IPAF inflammasome complex, mitochondrion, NLRP3 inflammasome complex, plasma membrane, protein-containing complex

apoptotic process, cellular response to amyloid-beta, execution phase of apoptosis, inflammatory response, innate immune response, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, positive regulation of tumor necrosis factor-mediated signaling pathway, protein autoprocessing, proteolysis, pyroptosis, regulation of apoptotic process, regulation of inflammatory response

7797510

19

271:289

SPASLEVASSQSSENLEED

PSQ01326

FD00129

Vascular endothelial growth factor C

P49767

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Homo sapiens (Human)

80

chemoattractant activity, growth factor activity, vascular endothelial growth factor receptor 3 binding, vascular endothelial growth factor receptor binding

420

Flt4 ligand, Vascular endothelial growth factor-related protein

VEGFC

9606

extracellular region, extracellular space, membrane, platelet alpha granule lumen

animal organ morphogenesis, cellular response to leukemia inhibitory factor, induction of positive chemotaxis, morphogenesis of embryonic epithelium, negative regulation of blood pressure, negative regulation of osteoblast differentiation, platelet degranulation, positive regulation of angiogenesis, positive regulation of blood vessel endothelial cell migration, positive regulation of cell division, positive regulation of cell population proliferation, positive regulation of endothelial cell proliferation, positive regulation of lymphangiogenesis, positive regulation of mast cell chemotaxis, positive regulation of mesenchymal stem cell proliferation, positive regulation of neuroblast proliferation, positive regulation of protein autophosphorylation, positive regulation of protein kinase activity, positive regulation of protein phosphorylation, positive regulation of protein secretion, regulation of vascular endothelial growth factor receptor signaling pathway, response to drug, response to hypoxia, signal transduction, sprouting angiogenesis, substrate-dependent cell migration, vascular endothelial growth factor receptor signaling pathway, vascular endothelial growth factor signaling pathway

9233800

80

32:111

FESGLDLSDAEPDAGEATAYASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSRTEETIKFAA

PSQ01327

FD00550

Cathelicidin antimicrobial peptide

P49913

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Homo sapiens (Human)

101

lipopolysaccharide binding

170

18 kDa cationic antimicrobial protein

CAMP

9606

extracellular exosome, extracellular region, extracellular space, specific granule, specific granule lumen, tertiary granule lumen

antibacterial humoral response, antifungal humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, antimicrobial humoral response, chronic inflammatory response, cytolysis by host of symbiont cells, defense response to bacterium, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, innate immune response, innate immune response in mucosa, killing by host of symbiont cells, modulation of process of other organism, neutrophil degranulation, positive regulation of interleukin-8 production, response to yeast

7615076

101

31:131

QVLSYKEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARGSFDISCDKDNKR

PSQ01328

FD00301

Adenylate kinase

P49983

Eukaryota Metamonada Parabasalia Trichomonadida Trichomonadidae Trichomonas

Trichomonas vaginalis

9

adenylate kinase activity, ATP binding

229

ATP-AMP transphosphorylase, ATP, Adenylate monophosphate kinase

None

5722

hydrogenosome

None

7808479

9

1:9

MLSTLAKRF

PSQ01329

FD00587

Matrix metalloproteinase-14

P50281

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Homo sapiens (Human)

91

endopeptidase activity, integrin binding, metalloaminopeptidase activity, metalloendopeptidase activity, zinc ion binding

582

MMP-X1, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase

MMP14

9606

cytoplasmic vesicle, cytosol, extracellular matrix, extracellular space, focal adhesion, Golgi lumen, integral component of plasma membrane, intermediate filament cytoskeleton, macropinosome, melanosome, nucleus, plasma membrane

angiogenesis, astrocyte cell migration, branching morphogenesis of an epithelial tube, cell motility, chondrocyte proliferation, collagen catabolic process, craniofacial suture morphogenesis, embryonic cranial skeleton morphogenesis, endochondral ossification, endodermal cell differentiation, endothelial cell proliferation, extracellular matrix disassembly, extracellular matrix organization, head development, lung development, male gonad development, negative regulation of focal adhesion assembly, negative regulation of Notch signaling pathway, ovarian follicle development, positive regulation of B cell differentiation, positive regulation of cell growth, positive regulation of cell migration, positive regulation of macrophage migration, positive regulation of myotube differentiation, positive regulation of protein processing, protein processing, proteolysis, regulation of protein localization to plasma membrane, response to estrogen, response to hypoxia, response to mechanical stimulus, response to odorant, response to organic cyclic compound, response to oxidative stress, skeletal system development, tissue remodeling, zymogen activation

8804434

91

21:111

ALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKR

PSQ01330

FD00306

Exoglucanase B

P50899

Bacteria Actinobacteria Micrococcales Cellulomonadaceae Cellulomonas

Cellulomonas fimi (strain ATCC 484 , NCIMB 8980

20

cellulase activity, cellulose 1,4-beta-cellobiosidase activity, polysaccharide binding

1090

1, CBP120, Exocellobiohydrolase B

cbhB

590998

None

cellulose catabolic process

8147863, 8458833

20

34:53

AAGAGQPATVTVPAASPVRA

PSQ01331

FD00006

Alpha-conotoxin EI

P50982

Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Neogastropoda Conoidea Conidae Conus Chelyconus

Conus ermineus (Atlantic fish-hunting cone)

27

acetylcholine receptor inhibitor activity, toxin activity

62

None

55423

extracellular region, host cell postsynaptic membrane

modulation of receptor activity in other organism, pathogenesis

7578057

27

17:43

FTLDRASDGRDAAANDKASDLIALTAR

PSQ01332

FD00006

Alpha-conotoxin PnIB

P50985

Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Neogastropoda Conoidea Conidae Conus Darioconus

Conus pennaceus (Feathered cone) (Conus episcopus)

23

acetylcholine receptor inhibitor activity, toxin activity

61

None

37335

extracellular region, host cell postsynaptic membrane

pathogenesis

8068627

23

22:44

FTSDRASDDGNAAASDLIALTIK

PSQ01333

FD00007

Trypsin

P51588

Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Diptera Brachycera Muscomorpha Oestroidea Sarcophagidae Sarcophaga Neobellieria

Sarcophaga bullata (Grey flesh fly) (Neobellieria bullata)

10

serine-type endopeptidase activity

254

None

7385

extracellular space

digestion

8620885

10

17:26

GTLPNDLDGR

PSQ01334

FD00480

Metallo-beta-lactamase L1 type 3

P52700

Bacteria Proteobacteria Gammaproteobacteria Xanthomonadales Xanthomonadaceae Stenotrophomonas Stenotrophomonas maltophilia group

Stenotrophomonas maltophilia (Pseudomonas maltophilia) (Xanthomonas, maltophilia)

12

beta-lactamase activity, zinc ion binding

290

B3 metallo-beta-lactamase , Beta-lactamase type III , Metallo-beta-lactamase L1 type III , Penicillinase

None

40324

periplasmic space

antibiotic catabolic process, response to antibiotic

3931629

12

22:33

AEVPLPQLRAYT

PSQ01335

FD00407

Carboxypeptidase Y

P52710

Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Phaffomycetaceae Komagataella

Komagataella phaffii (strain GS115

87

serine-type carboxypeptidase activity

523

Carboxypeptidase YSCY

PRC1

644223

extracellular region, fungal-type vacuole lumen

macroautophagy, phytochelatin biosynthetic process, zymogen activation

8789258

87

21:107

LSLQMPMALEASYASLVEKATLAVGQEIDAIQKGIQQGWLEVETRFPTIVSQLSYSTGPKFAIKKKDATFWDFYVESQELPNYRLRV

PSQ01336

FD00162

Serine-type carboxypeptidase F

P52718

Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Circumdati

Aspergillus niger

27

serine-type carboxypeptidase activity

538

CPD-II

pepF

5061

None

1637154

27

26:52

HGRFGQKARDAMNIAKRSANAVKHSLK

PSQ01337

FD00393

Probable alcohol acetyltransferase

P53219

Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces

Saccharomyces cerevisiae (strain ATCC 204508

8

hydrolase activity, transferase activity

342

Intermediate cleaved by mitochondrial octapeptidyl aminopeptidase protein 32

IMO32

559292

mitochondrion

None

21525245

8

39:46

FHSLAKVL

PSQ01338

FD00166

Probable family 17 glucosidase SCW4

P53334

Eukaryota Fungi Dikarya Ascomycota Saccharomycotina Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces

Saccharomyces cerevisiae (strain ATCC 204508

11

1,3-beta-glucanosyltransferase activity, glucan endo-1,3-beta-D-glucosidase activity, glucosidase activity, mRNA binding

386

Soluble cell wall protein 4

SCW4

559292

cell surface, extracellular region, fungal-type cell wall, fungal-type vacuole, vacuole

carbohydrate metabolic process, cell wall organization, conjugation with cellular fusion

9748433

11

20:30

APANHEHKDKR

PSQ01339

FD00499

Dipeptidyl peptidase 1

P53634

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Homo sapiens (Human)

96

chaperone binding, chloride ion binding, cysteine-type endopeptidase activity, cysteine-type peptidase activity, dipeptidyl-peptidase activity, identical protein binding, peptidase activator activity involved in apoptotic process, phosphatase binding, protein self-association, serine-type endopeptidase activity

463

Cathepsin C, Cathepsin J, Dipeptidyl peptidase I, Dipeptidyl transferase

CTSC

9606

azurophil granule lumen, centrosome, collagen-containing extracellular matrix, COPII-coated ER to Golgi transport vesicle, endoplasmic reticulum lumen, endoplasmic reticulum-Golgi intermediate compartment membrane, extracellular exosome, extracellular region, extracellular space, Golgi apparatus, intracellular membrane-bounded organelle, lysosome, membrane, nucleoplasm

aging, COPII vesicle coating, endoplasmic reticulum to Golgi vesicle-mediated transport, immune response, negative regulation of myelination, neutrophil degranulation, positive regulation of apoptotic signaling pathway, positive regulation of microglial cell activation, positive regulation of proteolysis involved in cellular protein catabolic process, proteolysis, proteolysis involved in cellular protein catabolic process, response to organic substance, T cell mediated cytotoxicity

1586157, 7665576, 9507095

96

135:230

ACFTGKKVGTASENVYVNIAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILH

PSQ01340

FD00580

Protein MoaF

P54796

Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Enterobacteriaceae Klebsiella

Klebsiella aerogenes (Enterobacter aerogenes)

13

None

262

None

moaF

548

None

7590328

13

1:13

MTSEAVFIQVGAL

PSQ01341

FD00120

Caspase-7

P55214

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Cricetidae Cricetinae Mesocricetus

Mesocricetus auratus (Golden hamster)

22

cysteine-type endopeptidase activity

303

Apoptotic protease Mch-3, ICE-like apoptotic protease 3, SREBP cleavage activity 2

CASP7

10036

cytoplasm

apoptotic process

8643593

22

2:23

ADDQNCAPELEKADPSGEDGVD

PSQ01342

FD00030

Aspergillopepsin-1

P55325

Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Circumdati

Aspergillus niger

49

aspartic-type endopeptidase activity

394

Aspartic protease pepA, Aspergillopepsin I, Aspergillopeptidase A, Proctase B

pepA

5061

extracellular region

None

7787314

49

21:69

APAPTRKGFTINQIARPANKTRTVNLPGLYARSLAKFGGTVPQSVKEAA

PSQ01343

FND00253

Lebocin-3

P55796

Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Lepidoptera Glossata Ditrysia Bombycoidea Bombycidae Bombycinae Bombyx

Bombyx mori (Silk moth)

104

None

180

None

LEB3

7091

extracellular region

defense response to bacterium, innate immune response

7654207

104

17:120

QASCQRFIQPTFRPPPTQRPITRTVRQAGQEPLWLYQGDNVPRAPSTADHPILPSKIDDVQLDPNRRYVRSVTNPENNEASIEHSHHTVDIGLDQPIESHRNTR

PSQ01344

FD00297

Small ubiquitin-related modifier 3

P55854

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Homo sapiens (Human)

11

protein tag, ubiquitin-like protein ligase binding

103

SMT3 homolog 1 , SUMO-2 , Ubiquitin-like protein SMT3A

SUMO3

9606

cytoplasm, kinetochore, nucleoplasm, nucleus, PML body

negative regulation of DNA binding, protein sumoylation, regulation of protein localization to nucleus

15487983, 16608850

11

93:103

VPESSLAGHSF

PSQ01345

FD00446

Gastrin

P55885

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Perissodactyla Equidae Equus

Equus caballus (Horse)

40

hormone activity

107

None

GAST

9796

extracellular space

G protein-coupled receptor signaling pathway, response to food

9716385

40

22:61

SWKPCSQLQDAPSGPGANKGLYPHWPDQLDRLGPASHHRR

PSQ01346

FD00294

Phospholipase D alpha 2

P55939

Reviewed 812 AA Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Brassiceae Brassica

Brassica oleracea var

36

calcium ion binding, N-acylphosphatidylethanolamine-specific phospholipase D activity, phospholipase D activity

812

Choline phosphatase 2, Phosphatidylcholine-hydrolyzing phospholipase D 2

PLD2

3716

cytoplasm, membrane

lipid catabolic process, phosphatidylcholine metabolic process

8353126

36

1:36

MAQHLLHGTLHATIYEVDALHTGGLRSAGFLGKIIS

PSQ01347

FD00085

Aspartic protease 3

P55956

Eukaryota Metazoa Ecdysozoa Nematoda Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis

Caenorhabditis elegans

38

aspartic-type endopeptidase activity

398

None

asp-3

6239

cytoplasm, extracellular region, lysosome

cell death, necrotic cell death, programmed cell death

9150941

38

18:55

IQRIKLEKRTYTREQYKFGSIQEHLKAKYVPGYIPNKD

PSQ01348

FD00033

Alpha-conotoxin PIVA

P55963

Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Neogastropoda Conoidea Conidae Conus Chelyconus

Conus purpurascens (Purple cone)

25

acetylcholine receptor inhibitor activity, toxin activity

68

Alpha-A-conotoxin PIVA

None

41690

extracellular region, host cell postsynaptic membrane

pathogenesis

7673220

25

17:41

FTSDRASDDRNTNDKASRLLSHVVR

PSQ01349

FD00168

Probable insulin-like peptide beta-type 5

P56174

Eukaryota Metazoa Ecdysozoa Nematoda Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis

Caenorhabditis elegans

39

hormone activity, insulin receptor binding

119

None

ins-6

6239

extracellular space

cellular response to salt, chemosensory behavior, dauer larval development, insulin receptor signaling pathway, negative regulation of dauer entry, olfactory learning, regulation of synaptic growth at neuromuscular junction

23665919

39

20:58

FRQSFGPSMSEESASMQLLRELQHNMMESAHRPMPRARR

PSQ01350

FD00002

Frenatin-3

P56249

Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Hylidae Pelodryadinae Nyctimystes

Nyctimystes infrafrenatus (White-lipped tree frog) (Litoria infrafrenata)

24

None