Details of family id : FD00017
Family ID |
FD00017 |
Protein Name |
Coagulation factor IX ; Vitamin K-dependent protein C; Venom prothrombin activator pseutarin-C catalytic subunit; Coagulation factor X; Coagulation factor VII; Venom prothrombin activator trocarin-D; Venom prothrombin activator hopsarin-D |
UniProt ID |
P00740
P00745
Q56VR3
P00742
P00743
P25155
P22457
P81428
P83370
P08709
|
Prosequence Length Range (aa) |
9-55
|
Preproprotein Length Range(aa) |
447-492 |
Preproprotein pI Range |
5.34-8.07 |
Preproprotein Molecular Weight Range (D) |
48960.7-54731.69 |
Prosequence pI Range (D) |
3.9-12.31 |
Prosequence Molecular Weight Range |
1056.23-5774.13 |
Domains |
cd00054 : cd00190 : pfam14670 : smart00069 |
Organisms |
Homo sapiens (Human); Bos taurus (Bovine); Pseudonaja textilis (Eastern brown snake); Gallus gallus (Chicken); Tropidechis carinatus (Australian rough-scaled snake); Hoplocephalus stephensii (Stephens |
Functions |
calcium ion binding; endopeptidase activity; serine-type endopeptidase activity; peptidase activator activity; toxin activity; phospholipid binding; serine-type peptidase activity; signaling receptor binding |
Cellular Localization |
collagen-containing extracellular matrix; endoplasmic reticulum lumen; extracellular exosome; extracellular region; extracellular space; Golgi lumen; plasma membrane; endoplasmic reticulum; Golgi apparatus; protein-containing complex; intrinsic component of external side of plasma membrane; serine-type peptidase complex; vesicle |
Processes |
blood coagulation; intrinsic pathway; endoplasmic reticulum to Golgi vesicle-mediated transport; proteolysis; zymogen activation; negative regulation of apoptotic process; negative regulation of blood coagulation; negative regulation of coagulation; negative regulation of inflammatory response; positive regulation of establishment of endothelial barrier; envenomation resulting in positive regulation of blood coagulation in other organism; positive regulation of blood coagulation in other organism; extrinsic pathway; positive regulation of cell migration; positive regulation of protein kinase B signaling; positive regulation of leukocyte chemotaxis; positive regulation of platelet-derived growth factor receptor signaling pathway; positive regulation of positive chemotaxis; protein processing; animal organ regeneration; circadian rhythm; positive regulation of blood coagulation; response to 2,3,7,8-tetrachlorodibenzodioxine; response to anticoagulant; response to astaxanthin; response to carbon dioxide; response to cholesterol; response to estradiol; response to estrogen; response to genistein; response to growth hormone; response to hypoxia; response to Thyroid stimulating hormone; response to thyrotropin-releasing hormone; response to thyroxine; response to vitamin K |
Common Name |
Coagulation factor IX; vitamin K dependent protein C; venom prothrombin activator pseutarin C catalytic subunit; coagulation factor X; coagulation factor VII; venom prothombin activator trocarin; venom prothombin activator hopsarin |