Details of family id : FD00083
| Family ID |
FD00083 |
| Protein Name |
Cathepsin S; Vignain; Pro-cathepsin H; Cysteine protease Amb a 11 |
| UniProt ID |
P25326
P12412
P09668
V5LU01
|
| Prosequence Length Range (aa) |
16-106
|
| Preproprotein Length Range(aa) |
331-386 |
| Preproprotein pI Range |
5.86-8.35 |
| Preproprotein Molecular Weight Range (D) |
37176.03-43156.93 |
| Prosequence pI Range (D) |
7.16-11.0 |
| Prosequence Molecular Weight Range |
1898.28-12675.2 |
| Domains |
pfam00112 : pfam08246 |
| Organisms |
Bos taurus (Bovine); Vigna mungo (Black gram) (Phaseolus mungo); Homo sapiens (Human); Ambrosia artemisiifolia (Short ragweed) |
| Functions |
collagen binding; cysteine-type endopeptidase activity; fibronectin binding; laminin binding; proteoglycan binding; cysteine-type peptidase activity; aminopeptidase activity; cysteine-type endopeptidase activator activity involved in apoptotic process; endopeptidase activity; HLA-A specific activating MHC class I receptor activity; peptidase activity; serine-type endopeptidase activity; thyroid hormone binding; protein homodimerization activity |
| Cellular Localization |
extracellular space; late endosome; lysosome; phagocytic vesicle; aleurone grain; endoplasmic reticulum lumen; vacuole; alveolar lamellar body; collagen-containing extracellular matrix; cytoplasmic ribonucleoprotein granule; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; intracellular membrane-bounded organelle; multivesicular body lumen; secretory granule lumen; tertiary granule lumen; |
| Processes |
adaptive immune response; antigen processing and presentation of exogenous peptide antigen via MHC class II; basement membrane disassembly; cellular response to thyroid hormone stimulus; collagen catabolic process; immune response; positive regulation of cation channel activity; protein processing; proteolysis involved in cellular protein catabolic process; response to acidic pH; ; antigen processing and presentation; bradykinin catabolic process; cellular protein metabolic process; dichotomous subdivision of terminal units involved in lung branching; ERK1 and ERK2 cascade; immune response-regulating signaling pathway; membrane protein proteolysis; metanephros development; negative regulation of apoptotic process; neuropeptide catabolic process; neutrophil degranulation; positive regulation of angiogenesis; positive regulation of cell migration; positive regulation of cell population proliferation; positive regulation of epithelial cell migration; positive regulation of gene expression; positive regulation of peptidase activity; protein destabilization; proteolysis; response to retinoic acid; surfactant homeostasis; T cell mediated cytotoxicity; zymogen activation |
| Common Name |
Cathepsin S; Vignain; cathepsin; Cysteine protease Amb |
