Details of family id : FD00004
| Family ID |
FD00004 |
| Protein Name |
Snake venom serine protease 2; Thrombin-like enzyme bhalternin; Trypsin; Thrombin-like enzyme CPI-enzyme 2; Haptoglobin; Kallikrein-14; Blarina toxin; Thrombin-like enzyme barnettobin; Tryptase beta-2; Tryptase; Trypsin-1; Snake venom serine protease catroxase-2; Snake venom serine protease homolog; Serine protease 30; Snake venom serine protease HS114 ; Venom plasminogen activator LV-PA; Thrombin-like enzyme asperase; Snake venom serine protease catroxase-1; Snake venom serine protease BPA; Mastin; Thrombin-like enzyme cerastocytin; Chymotrypsin-like elastase family member 1; Collagenase; Chymotrypsin-C; Prostate-specific antigen; Azurocidin ; Kallikrein 1-related peptidase b3; Blarinasin-1; Glandular kallikrein-10; Kallikrein 1-related peptidase b16 |
| UniProt ID |
Q9DF67
P0CG03
P00764
O42207
P19006
Q9P0G3
Q76B45
K4LLQ2
P21845
P27435
P16049
Q8QHK2
B0ZT25
P83748
Q5W959
Q27J47
Q072L6
Q8QHK3
Q9PTU8
P19236
P00761
Q7SYF1
P00772
P08897
Q7M3E1
P07288
P20160
P80015
P00756
Q5FBW2
P36375
P04071
|
| Prosequence Length Range (aa) |
6-186
|
| Preproprotein Length Range(aa) |
229-329 |
| Preproprotein pI Range |
4.64-11.64 |
| Preproprotein Molecular Weight Range (D) |
24409.48-36457.37 |
| Prosequence pI Range (D) |
3.77-12.0 |
| Prosequence Molecular Weight Range |
640.7-26215.5 |
| Domains |
cd00190 |
| Organisms |
Protobothrops jerdonii (Jerdon; Bothrops alternatus (Urutu) (Rhinocerophis alternatus); Squalus acanthias (Spiny dogfish); Gloydius ussuriensis (Ussuri mamushi) (Gloydius blomhoffii ussuriensis); Canis lupus familiaris (Dog) (Canis familiaris); Homo sapiens (Human); Blarina brevicauda (Northern short-tailed shrew); Bothrops barnetti (Barnett; Mus musculus (Mouse); Rattus norvegicus (Rat); Gadus morhua (Atlantic cod); Crotalus atrox (Western diamondback rattlesnake); Bothrops jararaca (Jararaca) (Bothrops jajaraca); Lachesis muta muta (Bushmaster); Bothrops asper (Terciopelo); Sus scrofa (Pig); Cerastes cerastes (Horned desert viper); Hypoderma lineatum (Early cattle grub) (Common cattle grub); Bos taurus (Bovine) |
| Functions |
serine-type endopeptidase activity; toxin activity; metal ion binding; antioxidant activity; hemoglobin binding; heparin binding; identical protein binding; peptidase activity; sodium channel regulator activity; endopeptidase activity; serine-type peptidase activity; hydrolase activity; acting on carbon-nitrogen (but not peptide) bonds; in linear amides; heparan sulfate proteoglycan binding; toxic substance binding; growth factor activity |
| Cellular Localization |
extracellular region; extracellular space; blood microparticle; secretory granule; mast cell granule; anchored component of plasma membrane; cytoplasm; extracellular exosome; nucleus; protein-containing complex; azurophil granule; azurophil granule lumen; azurophil granule membrane; extrinsic component of membrane; intracellular membrane-bounded organelle |
| Processes |
hemolysis in other organism; digestion; acute inflammatory response; acute-phase response; defense response to bacterium; immune system process; positive regulation of cell death; zymogen activation; cornification; epidermis morphogenesis; fertilization; negative regulation of G protein-coupled receptor signaling pathway; positive regulation of G protein-coupled receptor signaling pathway; proteolysis; seminal clot liquefaction; inflammatory response; extracellular matrix disassembly; sodium ion transport; regulation of blood pressure; apoptotic process; cell death; cytolysis; innate immune response; T cell mediated cytotoxicity; collagen catabolic process; cellular protein metabolic process; negative regulation of angiogenesis; positive regulation of antibacterial peptide production; regulation of androgen receptor signaling pathway; regulation of systemic arterial blood pressure; antimicrobial humoral response; calcium-mediated signaling using intracellular calcium source; cell chemotaxis; cellular extravasation; defense response to Gram-negative bacterium; defense response to virus; glial cell migration; induction of positive chemotaxis; macrophage chemotaxis; microglial cell activation; monocyte activation; negative regulation of apoptotic process; neutrophil degranulation; neutrophil-mediated killing of bacterium; positive regulation of cell adhesion; positive regulation of fractalkine production; positive regulation of gene expression; positive regulation of interleukin-1 beta production; positive regulation of MHC class II biosynthetic process; positive regulation of peptidyl-threonine phosphorylation; positive regulation of phagocytosis; positive regulation of protein kinase activity; positive regulation of tumor necrosis factor production; protein kinase C signaling; protein kinase C-activating G protein-coupled receptor signaling pathway; regulation of vascular permeability |
| Common Name |
snake venom serine protease; thrombin like enzyme bhalternin; Trypsin; thrombin like enzyme CPI enzyme; Haptoglobin; Kallikrein; blarina toxin; thrombin like enzyme barnettobin; Tryptase; snake venom serine protease catroxase; snake venom serine protease homolog; snake protease; snake venom serine protease; venom plasminogen activator; thrombin like enzyme asperase; Mastin; thrombin like enzyme cerastocytin; chymotrypsin like elastase family member; Granzyme; Collagenase; Chymotrypsin; Prostate; Azurocidin; Kallikrein-1 related peptidase; Blarinasin; Glandular kallikrein |
