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Details of family id : FD00142

Family ID FD00142
Protein Name Proteasome subunit beta type-4
UniProt ID P28070 P34067
Prosequence Length Range (aa) 44-45
Preproprotein Length Range(aa) 263-264
Preproprotein pI Range 5.7-6.44
Preproprotein Molecular Weight Range (D) 29197.29-29204.24
Prosequence pI Range (D) 8.0-8.34
Prosequence Molecular Weight Range 4830.47-4848.53
Domains cd03760
Organisms Homo sapiens (Human); Rattus norvegicus (Rat)
Functions endopeptidase activity; lipopolysaccharide binding; threonine-type endopeptidase activity
Cellular Localization ciliary basal body; cytoplasm; cytosol; extracellular exosome; mitochondrion; nucleoplasm; nucleus; proteasome complex; proteasome core complex; beta-subunit complex
Processes anaphase-promoting complex-dependent catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; TAP-dependent; Fc-epsilon receptor signaling pathway; interleukin-1-mediated signaling pathway; MAPK cascade; negative regulation of canonical Wnt signaling pathway; negative regulation of G2/M transition of mitotic cell cycle; negative regulation of inflammatory response to antigenic stimulus; NIK/NF-kappaB signaling; positive regulation of canonical Wnt signaling pathway; post-translational protein modification; pre-replicative complex assembly; proteasomal ubiquitin-independent protein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process; protein deubiquitination; protein polyubiquitination; regulation of cellular amino acid metabolic process; regulation of hematopoietic stem cell differentiation; regulation of mitotic cell cycle phase transition; regulation of mRNA stability; regulation of transcription from RNA polymerase II promoter in response to hypoxia; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; stimulatory C-type lectin receptor signaling pathway; T cell receptor signaling pathway; transmembrane transport; tumor necrosis factor-mediated signaling pathway; viral process; Wnt signaling pathway; planar cell polarity pathway
Common Name Proteasome subunit beta type