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Details of family id : FD00118

Family ID FD00118
Protein Name Alpha-2-antiplasmin
UniProt ID P08697 P28800 Q61247
Prosequence Length Range (aa) 12-18
Preproprotein Length Range(aa) 491-492
Preproprotein pI Range 5.45-5.87
Preproprotein Molecular Weight Range (D) 54565.76-54971.93
Prosequence pI Range (D) 3.49-5.75
Prosequence Molecular Weight Range 1285.48-2008.29
Domains cd02053
Organisms Homo sapiens (Human); Bos taurus (Bovine); Mus musculus (Mouse)
Functions endopeptidase inhibitor activity; protease binding; protein homodimerization activity; serine-type endopeptidase inhibitor activity
Cellular Localization blood microparticle; cell surface; collagen-containing extracellular matrix; extracellular exosome; extracellular region; extracellular space; fibrinogen complex; platelet alpha granule lumen
Processes acute-phase response; blood vessel morphogenesis; collagen fibril organization; fibrinolysis; maintenance of blood vessel diameter homeostasis by renin-angiotensin; negative regulation of endopeptidase activity; negative regulation of fibrinolysis; negative regulation of plasminogen activation; platelet degranulation; positive regulation of cell differentiation; positive regulation of cell-cell adhesion mediated by cadherin; positive regulation of collagen biosynthetic process; positive regulation of ERK1 and ERK2 cascade; positive regulation of JNK cascade; positive regulation of smooth muscle cell proliferation; positive regulation of stress fiber assembly; positive regulation of transcription by RNA polymerase II; positive regulation of transforming growth factor beta production; response to organic substance
Common Name Alpha 2 antiplasmin