Details of family id : FD00118
Family ID |
FD00118 |
Protein Name |
Alpha-2-antiplasmin |
UniProt ID |
P08697
P28800
Q61247
|
Prosequence Length Range (aa) |
12-18
|
Preproprotein Length Range(aa) |
491-492 |
Preproprotein pI Range |
5.45-5.87 |
Preproprotein Molecular Weight Range (D) |
54565.76-54971.93 |
Prosequence pI Range (D) |
3.49-5.75 |
Prosequence Molecular Weight Range |
1285.48-2008.29 |
Domains |
cd02053 |
Organisms |
Homo sapiens (Human); Bos taurus (Bovine); Mus musculus (Mouse) |
Functions |
endopeptidase inhibitor activity; protease binding; protein homodimerization activity; serine-type endopeptidase inhibitor activity |
Cellular Localization |
blood microparticle; cell surface; collagen-containing extracellular matrix; extracellular exosome; extracellular region; extracellular space; fibrinogen complex; platelet alpha granule lumen |
Processes |
acute-phase response; blood vessel morphogenesis; collagen fibril organization; fibrinolysis; maintenance of blood vessel diameter homeostasis by renin-angiotensin; negative regulation of endopeptidase activity; negative regulation of fibrinolysis; negative regulation of plasminogen activation; platelet degranulation; positive regulation of cell differentiation; positive regulation of cell-cell adhesion mediated by cadherin; positive regulation of collagen biosynthetic process; positive regulation of ERK1 and ERK2 cascade; positive regulation of JNK cascade; positive regulation of smooth muscle cell proliferation; positive regulation of stress fiber assembly; positive regulation of transcription by RNA polymerase II; positive regulation of transforming growth factor beta production; response to organic substance |
Common Name |
Alpha 2 antiplasmin |