PSQ01951
FD00514
Acetylxylan esterase A
Q8NJP6
Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Trichocomaceae Talaromyces Talaromyces sect Talaromyces
Talaromyces purpureogenus (Soft rot fungus) (Penicillium purpureogenum)
10
acetylxylan esterase activity, cellulose binding
382
AXE I, Acetylxylan esterase 1
axeA
1266744
extracellular region
cellulose catabolic process, xylan catabolic process
17008082, 8756392
10
22:31
RTLGKDVNKR
PSQ01952
FD00070
Aorsin
Q8NK92
Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Circumdati
Aspergillus oryzae (strain ATCC 42149
193
metal ion binding, serine-type endopeptidase activity
659
None
aorO
510516
extracellular region, extracellular space
proteolysis
12519073
193
23:215
ATSVVHERREATSSNWVKRARVNPSDKHVVRIGLTQSSLEEAHDLLMDVSNPSSPNYARFYSADEVAAKFAPSTETVNEVQNWLTEKGINASRVAQTQNHGWLVFHATSKEIENLFDTTYYEYHNRKTGKKAIACEQYHVPASVQKHIDYVHPGVNLNPSSGKPSSIRRRAAASKKTKLPARGPRPIQQHDVK
PSQ01953
FD00002
Ranatuerin-2P
Q8QFQ4
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Ranoidea Ranidae Lithobates
Lithobates pipiens (Northern leopard frog) (Rana pipiens)
24
None
71
None
None
8404
extracellular region
defense response to bacterium, defense response to fungus, killing of cells of other organism
10651828
24
21:44
LCEQERGADEDDGVEITEEEVKRG
PSQ01954
FD00004
Snake venom serine protease catroxase-2
Q8QHK2
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Crotalus
Crotalus atrox (Western diamondback rattlesnake)
6
serine-type endopeptidase activity, toxin activity
258
Catroxase II, Kallikrein-like EI
None
8730
extracellular region
None
19371136, 6355088
6
19:24
QKSSEL
PSQ01955
FD00004
Snake venom serine protease catroxase-1
Q8QHK3
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Crotalus
Crotalus atrox (Western diamondback rattlesnake)
6
serine-type endopeptidase activity, toxin activity
262
Catroxase I
None
8730
extracellular region
None
19371136
6
19:24
QKSSEP
PSQ01956
FD00050
Interleukin-36 gamma
Q8R460
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus
Mus musculus (Mouse)
12
cytokine activity
164
Interleukin-1 family member 9
Il36g
10090
cytoplasm, extracellular space
cellular response to lipopolysaccharide, cytokine-mediated signaling pathway, inflammatory response, inflammatory response to antigenic stimulus, innate immune response, negative regulation of myoblast differentiation, negative regulation of myoblast fusion, positive regulation of cytokine production, positive regulation of gene expression, positive regulation of interleukin-6 production
21965679
12
1:12
MFSKHPFSTHIS
PSQ01957
FND00264
Arabinogalactan protein 23
Q8S2W4
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis
Arabidopsis thaliana (Mouse-ear cress)
26
None
61
Arabinogalactan peptide 23
AGP23
3702
anchored component of membrane, plasma membrane
None
15322080
26
36:61
AASAALPALGSLVGASLVSLFSYYLH
PSQ01958
FND00240
Neuropeptide CCHamide-2
Q8SXL2
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Diptera Brachycera Muscomorpha Ephydroidea Drosophilidae Drosophila Sophophora
Drosophila melanogaster (Fruit fly)
94
neuropeptide hormone activity
136
None
CCHa2
7227
extracellular space
neuropeptide signaling pathway
21214272, 23293632
94
43:136
SLSPGSGSGTGVGGGMGEAASGGQEPDYVRPNGLLPMMAPNEQVPLEGDFNDYPARQVLYKIMKSWFNRPRRPASRLGELDYPLANSAELNGVN
PSQ01959
FND00126
Lysozyme A
Q8T1G4
Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia Dictyosteliales Dictyosteliaceae Dictyostelium
Dictyostelium discoideum (Slime mold)
43
lysozyme activity
181
1
alyA
44689
cytoplasmic vesicle, cytoplasmic vesicle lumen, vesicle lumen
cytolysis, defense response to Gram-positive bacterium, peptidoglycan catabolic process, phagocytosis
15640146
43
139:181
LTDSRPLGPFNVTESEMAQLFIDHEIAMAQCEAEKTCNGFDLE
PSQ01960
FD00171
Moronecidin
Q8UUG0
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Neoteleostei Acanthomorphata Eupercaria Moronidae Morone
Morone saxatilis (Striped bass) (Perca saxatilis)
33
None
79
Piscidin-1
None
34816
extracellular region
defense response to bacterium, defense response to fungus, hemolysis in other organism
11713517
33
47:79
AEQDQQDQQYQQEQQEQQAQQYQRFNRERAAFD
PSQ01961
FD00013
Zinc metalloproteinase-disintegrin-like berythractivase
Q8UVG0
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Bothrops
Bothrops erythromelas (Caatinga lance head)
167
metal ion binding, metalloendopeptidase activity, peptidase activator activity, toxin activity
612
Snake venom metalloproteinase, ery1
None
44710
extracellular region
None
12225292
167
21:187
IILESGNVNDYEVVYPRKVTALSKGAVHPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSEDYSEIHYSPDGREITTYPLVEDHCYYHGRIQNDADSSASISACNGLKGHFKLQGEMYLIEPFKLPDSEAHAVFKYENVEKEDEAPKMCGVTETNWESDEPIKKASLLN
PSQ01962
FD00221
Bowman-Birk type proteinase inhibitor
Q8W4Y8
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Fabales Fabaceae Papilionoideae 50 kb inversion clade NPAAA clade Hologalegina IRL clade Fabeae Lens
Lens culinaris (Lentil) (Cicer lens)
14
serine-type endopeptidase inhibitor activity
110
LCTI, Trypsin
None
3864
extracellular region
None
15212472, 16889634
14
29:42
RFDSTSFITQVLSN
PSQ01963
FD00496
Cardioactive peptide
Q8WRC7
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Lepidoptera Glossata Ditrysia Bombycoidea Sphingidae Sphinginae Sphingini Manduca
Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)
20, 69
neuropeptide hormone activity
125
Cardioacceleratory peptide 2a, Crustacean cardioactive peptide
CCAP
7130
extracellular region
neuropeptide signaling pathway, positive regulation of heart contraction
1426284;1426284
89
23:42, 57:125
ASIPRNFDPRLSEEIVMAPK, RSQGPPGMPAQDLRTKQYLDEEALGSILDSESAIDELSRQILSEAKLWEAIQEASAEIARRKQKEAYIQ
PSQ01964
FD00211
Attacin-A
Q8WTD3
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Diptera Brachycera Muscomorpha Hippoboscoidea Glossinidae Glossina
Glossina morsitans morsitans (Savannah tsetse fly)
27
None
208
None
None
37546
extracellular region
antibacterial humoral response, defense response to Gram-negative bacterium, innate immune response
11886771
27
21:47
QFGGTVSSNPNGGLDVNARLSKTIGDP
PSQ01965
FND00166
Defensin-A
Q8WTD4
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Diptera Brachycera Muscomorpha Hippoboscoidea Glossinidae Glossina
Glossina morsitans morsitans (Savannah tsetse fly)
25
None
87
None
None
37546
extracellular region
antibacterial humoral response, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, innate immune response
11886771
25
20:44
LPAGDETRIDLETLEEDLRLVDGAQ
PSQ01966
FD00592
Internalin J
Q8Y3L4
Bacteria Firmicutes Bacilli Bacillales Listeriaceae Listeria
Listeria monocytogenes serovar 1
27
None
851
None
inlJ
169963
cell wall, extracellular region
cell adhesion, pathogenesis
18227172
27
825:851
GDSAPWKSALLGVFLSSTALVIWKKKK
PSQ01967
FD00341
Cell wall protein Lmo2714
Q8Y3W5
Bacteria Firmicutes Bacilli Bacillales Listeriaceae Listeria
Listeria monocytogenes serovar 1
29
None
315
Wall-associated protein lmo2714
None
169963
cell wall, extracellular region
None
11929538, 16247833
29
287:315
GDKGTEWIFVVAGVIVILVAVLLLRKRKK
PSQ01968
FD00571
Hemin
Q8Y585
Bacteria Firmicutes Bacilli Bacillales Listeriaceae Listeria
Listeria monocytogenes serovar 1
30
hemoglobin binding
207
Cell wall protein Lmo2186
hbp1
169963
extracellular region, peptidoglycan-based cell wall
cellular response to iron ion, heme transport, iron ion homeostasis
16247833
30
178:207
SDSSQMFLYGIIFVATGAGLILLKRRAIFK
PSQ01969
FD00233
Cell wall protein Lmo0880
Q8Y8L7
Bacteria Firmicutes Bacilli Bacillales Listeriaceae Listeria
Listeria monocytogenes serovar 1
26
collagen binding, lytic endotransglycosylase activity
462
None
None
169963
cell wall, extracellular region
cell adhesion
11929538, 16247833, 22837151
26
437:462
GDSNPFIPFVTGLSLIALGFTFGRKS
PSQ01970
FD00347
Cell wall protein Lmo0130
Q8YAJ5
Bacteria Firmicutes Bacilli Bacillales Listeriaceae Listeria
Listeria monocytogenes serovar 1
26
5, metal ion binding, nucleotide binding, UDP-sugar diphosphatase activity
784
None
None
169963
cell wall, extracellular region, outer membrane-bounded periplasmic space
nucleotide catabolic process
11929538, 16247833, 22837151
26
759:784
GDTAGLATVFGVILTTTALYVLRKRS
PSQ01971
FD00013
Zinc metalloproteinase-disintegrin-like ecarin
Q90495
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Viperinae Echis
Echis carinatus (Saw-scaled viper)
170
metal ion binding, metalloendopeptidase activity, peptidase activator activity, toxin activity
616
Snake venom metalloproteinase
None
40353
extracellular region
None
7849037
170
21:190
IILGSGNVNDYEVVYPQKVTALPKGAVQQPEQKYEDAMQYEFEVKGEPVVLHLEKNKELFSEDYSETHYSSDDREITTNPSVEDHCYYHGRIQNDAESTASISACNGLKGHFKLRGETYFIEPLKIPDSEAHAVYKYENIENEDEAPKMCGVTQDNWESDEPIKKTLGLI
PSQ01972
FD00569
72 kDa type IV collagenase
Q90611
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Archelosauria Archosauria Dinosauria Saurischia Theropoda Coelurosauria Aves Neognathae Galloanserae Galliformes Phasianidae Phasianinae Gallus
Gallus gallus (Chicken)
80
metalloendopeptidase activity, zinc ion binding
663
72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2
MMP2
9031
basement membrane, collagen-containing extracellular matrix, extracellular space, plasma membrane, sarcomere
blood vessel maturation, bone trabecula formation, cellular response to amino acid stimulus, cellular response to insulin-like growth factor stimulus, cellular response to reactive oxygen species, cellular response to UV-A, collagen catabolic process, endodermal cell differentiation, extracellular matrix organization, face morphogenesis, intramembranous ossification, negative regulation of cartilage condensation, negative regulation of cartilage development, negative regulation of focal adhesion assembly, negative regulation of protein phosphorylation, positive regulation of vascular associated smooth muscle cell proliferation, regulation of MAPK cascade, response to amyloid-beta, response to hypoxia, tissue remodeling
1848240
80
27:106
APSPIIKFPGDSTPKTDKELAVQYLNKYYGCPKDNCNLFVLKDTLKKMQKFFGLPETGDLDQNTIETMKKPRCGNPDVAN
PSQ01973
FD00010
Basic phospholipase A2 2
Q90WA8
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Elapidae Bungarinae Bungarus
Bungarus fasciatus (Banded krait) (Pseudoboa fasciata)
8
calcium ion binding, phospholipase A2 activity, phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine), phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine), toxin activity
145
KBf II , KBf-2, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2 isozyme II
None
8613
extracellular region
arachidonic acid secretion, lipid catabolic process, phospholipid metabolic process
17166178
8
20:27
ANIPPQSL
PSQ01974
FD00329
Ovochymase-2
Q90WD8
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Bufonidae Bufo
Bufo japonicus (Japanese toad)
28
metal ion binding, serine-type endopeptidase activity
974
Oviductal protease, Oviductin
OVCH2
8387
extracellular region
None
11846486
28
22:49
VTDSPGRVSRCGERPAANTSVSYGLLSR
PSQ01975
FD00015
Zinc metalloproteinase
Q90YA6
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Protobothrops
Protobothrops elegans (Elegant pitviper) (Trimeresurus elegans)
16
metal ion binding, metalloendopeptidase activity, toxin activity
481
None
None
88086
extracellular region
None
8920980
16
393:408
LRTDTVSTPVSGNEFL
PSQ01976
FD00013
Zinc metalloproteinase-disintegrin-like HV1
Q90ZI3
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Protobothrops
Protobothrops flavoviridis (Habu) (Trimeresurus flavoviridis)
168
metal ion binding, metalloendopeptidase activity, peptidase activator activity, toxin activity
612
Snake venom metalloproteinase, Vascular apoptosis-inducing protein
None
88087
extracellular region
apoptotic process
11389737
168
21:188
IILESGNVNDYEVVYPRKVTALPKGAVQQKYEDAMQYEFTVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTNPPVEDHCYYHGRIQNDADLTASISACDGLKGHFKLQGETYIIEPLKLPDSEAHAVFKYENVEKEDEAPKMCGVTQSNWESDESIKEDSQSNL
PSQ01977
FND00315
PYLa/PGLa B
Q91826
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Pipoidea Pipidae Xenopodinae Xenopus Xenopus
Xenopus laevis (African clawed frog)
15
None
64
None
pgla-b
8355
extracellular region
defense response to bacterium, defense response to fungus, hemolysis in other organism
6688991
15
21:35
EASALADADDDDDKR
PSQ01978
FD00058
Snake venom metalloproteinase ACLH
Q92032
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Agkistrodon
Agkistrodon contortrix laticinctus (Broad-banded copperhead) (Agkistrodon, mokasen laticinctus)
167
metal ion binding, metalloendopeptidase activity, toxin activity
407
ACL hemorrhagic toxin I, Hemorrhagic metalloproteinase ACLH
None
37195
extracellular region
None
8444323
167
21:187
IILESGNVNDYEVVYPRKVTPVPKGAVQPKYEDAMQYELKVNGEPVVLHLERNKGLFSKDYSETHYSPDGRKITTYPPVEDHCYYHGRIQNDADSIASISACNGLKGHFKLQGEMYLIEPLELSDSEAHAVFKYENVEKEDEAPKICGVTQNWESYEPIKKASQLNL
PSQ01979
FD00010
Neutral phospholipase A2 muscarinic inhibitor
Q92084
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Elapidae Elapinae Naja
Naja sputatrix (Malayan spitting cobra) (Naja naja sputatrix)
6
calcium ion binding, phospholipase A2 activity, phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine), phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine), toxin activity
146
NAJPLA-2A, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2 A
None
33626
extracellular region
arachidonic acid secretion, lipid catabolic process, phospholipid metabolic process
8638927, 9028006
6
22:27
NRPMPL
PSQ01980
FD00212
Catalase B
Q92405
Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus Aspergillus subgen Fumigati
Neosartorya fumigata (strain ATCC MYA-4609 , A1100) (Aspergillus fumigatus)
12
catalase activity, heme binding, metal ion binding
728
Antigenic catalase, Slow catalase
catB
330879
cell surface, cytosol, extracellular region
cellular response to hydrogen peroxide, cellular response to iron ion starvation, hydrogen peroxide catabolic process, response to oxidative stress
9353056
12
16:27
VCPYMTGELNRR
PSQ01981
FD00225
Sortilin-related receptor
Q92673
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
53
amyloid-beta binding, low-density lipoprotein particle binding, low-density lipoprotein particle receptor activity, neuropeptide binding, small GTPase binding, transmembrane signaling receptor activity
2220
Low-density lipoprotein receptor relative with 11 ligand-binding repeats, SorLA-1 , Sorting protein-related receptor containing LDLR class A repeats
SORL1
9606
cell surface, early endosome, early endosome membrane, endoplasmic reticulum, endoplasmic reticulum membrane, endosome, endosome membrane, extracellular exosome, extracellular space, Golgi apparatus, Golgi cisterna, Golgi membrane, integral component of membrane, integral component of plasma membrane, membrane, multivesicular body, multivesicular body membrane, nuclear envelope lumen, perinucleolar compartment, plasma membrane, recycling endosome, recycling endosome membrane, trans-Golgi network, transport vesicle membrane
adaptive thermogenesis, amyloid fibril formation, diet induced thermogenesis, insulin receptor recycling, negative regulation of amyloid-beta formation, negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process, negative regulation of BMP signaling pathway, negative regulation of MAP kinase activity, negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process, negative regulation of neurofibrillary tangle assembly, negative regulation of neurogenesis, negative regulation of neuron death, negative regulation of protein binding, negative regulation of protein-containing complex assembly, negative regulation of tau-protein kinase activity, negative regulation of triglyceride catabolic process, neuropeptide signaling pathway, positive regulation of adipose tissue development, positive regulation of choline O-acetyltransferase activity, positive regulation of early endosome to recycling endosome transport, positive regulation of endocytic recycling, positive regulation of ER to Golgi vesicle-mediated transport, positive regulation of glial cell-derived neurotrophic factor production, positive regulation of insulin receptor signaling pathway, positive regulation of protein catabolic process, positive regulation of protein exit from endoplasmic reticulum, positive regulation of protein localization to early endosome, post-Golgi vesicle-mediated transport, protein localization to Golgi apparatus, protein maturation, protein retention in Golgi apparatus, protein targeting, protein targeting to lysosome, receptor-mediated endocytosis, regulation of smooth muscle cell migration
8940146
53
29:81
EVWTQRLHGGSAPLPQDRGFLVVQGDPRELRLWARGDARGASRADEKPLRRKR
PSQ01982
FD00498
Fervidolysin
Q93LQ6
Bacteria Thermotogae Thermotogales Fervidobacteriaceae Fervidobacterium
Fervidobacterium pennivorans
128
calcium ion binding, peptidase activity, serine-type endopeptidase activity
699
Keratinase , Subtilisin-like serine protease
fls
93466
cell surface
protein autoprocessing, proteolysis
12072953
128
22:149
NPSFEPRSKAKDLASLPEIKSQGYHILFGELRDGEYTEGKILVGYNDRSEVDKIVKAVNGKVVLELPQIKVVSIKLNGMTVKQAYDKIKALALKGIRYVEPSYKRELIKPTVVKPNPDMYKIRKPGLN
PSQ01983
FND00048
Hydroxyproline-rich systemin B
Q93WP7
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae asterids lamiids Solanales Solanaceae Nicotianoideae Nicotianeae Nicotiana
Nicotiana tabacum (Common tobacco)
17, 89
hormone activity
164
None
None
4097
extracellular region
defense response
11459063;11459063
106
19:35, 54:142
RTLLENHEGLNVGSGYG, VSNSVSPTRTDEKTSENTELVMTTIAQGENSNQLFPFLTSSDNYQLASFKKLSISYLLPVSYVWKLISSSSFNHDLVDIFDTSSDEKYW
PSQ01984
FND00048
Hydroxyproline-rich systemin A
Q93WP8
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae asterids lamiids Solanales Solanaceae Nicotianoideae Nicotianeae Nicotiana
Nicotiana tabacum (Common tobacco)
17, 90
hormone activity
165
None
None
4097
extracellular region
defense response
11459063;11459063
107
19:35, 54:143
RTLLENHEGLNVGSGYG, VSNSVSPTRTDEKTSENTELVMTTIAQGENINQLFSFPTSADNYYQLASFKKLFISYLLPVSYVWNLIGSSSFDHDLVDIFDSKSDERYW
PSQ01985
FD00385
Snakin-2
Q93X17
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae asterids lamiids Solanales Solanaceae Solanoideae Solaneae Solanum
Solanum tuberosum (Potato)
15
None
104
None
SN2
4113
cell wall, extracellular region
defense response
11891250
15
24:38
IQTDQVTSNAISEAA
PSQ01986
FD00381
Stachyose synthase
Q93XK2
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Fabales Fabaceae Papilionoideae 50 kb inversion clade NPAAA clade Hologalegina IRL clade Fabeae Pisum
Pisum sativum (Garden pea)
11
galactinol-raffinose galactosyltransferase activity
853
Galactinol--raffinose galactosyltransferase
STS1
3888
cytoplasm
oligosaccharide biosynthetic process, stachyose biosynthetic process
11675396
11
1:11
MAPPLNSTTSN
PSQ01987
FD00366
Rapid alkalinization factor
Q945T0
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae asterids lamiids Solanales Solanaceae Nicotianoideae Nicotianeae Nicotiana
Nicotiana tabacum (Common tobacco)
43
hormone activity, receptor ligand activity
120
None
RALF
4097
extracellular region, plasmodesma
calcium-mediated signaling, regulation of signaling receptor activity
11675511
43
24:66
GDSGAYDWVMPARSGGGCKGSIGECIAEEEEFELDSESNRRIL
PSQ01988
FD00180
Cathepsin L 1
Q94714
Eukaryota Sar Alveolata Ciliophora Intramacronucleata Oligohymenophorea Peniculida Parameciidae Paramecium
Paramecium tetraurelia
85
cysteine-type endopeptidase activity
314
None
None
5888
extracellular space, lysosome
proteolysis involved in cellular protein catabolic process
8665938
85
25:109
LYANWKMKYNRRYTNQRDEMYRYKVFTDNLNYIRAFYESPEEATFTLELNQFADMSQQEFAQTYLSLKVPRTAKLNAANSNFQYK
PSQ01989
FD00082
Cathepsin B-like protease 3
Q94K85
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis
Arabidopsis thaliana (Mouse-ear cress)
76, 17
cysteine-type endopeptidase activity
360
Cathepsin B3
CATHB3
3702
cytosol, extracellular space, lysosome, secretory vesicle, vacuole
defense response, proteolysis involved in cellular protein catabolic process, regulation of catalytic activity
27058316;27058316
93
27:102, 343:359
GIEAESLTKQKLDSKILQDEIVKKVNENPNAGWKAAINDRFSNATVAEFKRLLGVKPTPKKHFLGVPIVSHDPSLK, NVFRVDTGSNDLPVASV
PSQ01990
FND00313
Basic proline-rich protein
Q95JC9
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Suina Suidae Sus
Sus scrofa (Pig)
49
hormone activity
676
None
None
9823
extracellular region
None
16112392
49
409:457
APPGARPPPPPPPPADEPQQGPAPSGDKPKKKPPPPAGPPPPGPPSPGP
PSQ01991
FD00107
Legumain
Q95M12
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Bovinae Bos
Bos taurus (Bovine)
8
cysteine-type endopeptidase activity
433
Asparaginyl endopeptidase, Protease
LGMN
9913
lysosome
negative regulation of ERBB signaling pathway, proteolysis, proteolysis involved in cellular protein catabolic process, receptor catabolic process, renal system process
11983426
8
18:25
VPLEDPED
PSQ01992
FD00098
PBAN-type neuropeptides
Q95P48
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Lepidoptera Glossata Ditrysia Noctuoidea Noctuidae Amphipyrinae Spodoptera
Spodoptera littoralis (Egyptian cotton leafworm)
44, 23
neuropeptide hormone activity
191
None
None
7109
extracellular region
neuropeptide signaling pathway, pheromone biosynthetic process
28502715;28502715
67
48:91, 169:191
SLRISTEDNRQAFFKLLEAADALKYYYDRLPYEMQADEPETRVT, ELSYDMLPSKLRLVRSTNRTQST
PSQ01993
FD00015
Zinc metalloproteinase
Q98SP2
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Bothrops
Bothrops jararaca (Jararaca) (Bothrops jajaraca)
167
metal ion binding, metalloendopeptidase activity, toxin activity
480
None
None
8724
extracellular region
None
1523677
167
21:187
IILESGNVNDYEVIYPRKVTALPKGAVQPKYEDAMQYELKVNGEPVVLHLEKNKGLFSKDYSETHYSPDGRKITTNPPVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGETYLIEPLKLSDSEAHAVFKFENVEKEDEAPKMCGVTQNWESYEPIKKASQSNL
PSQ01994
FND00346
Ice-structuring protein B
Q99013
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Neoteleostei Acanthomorphata Carangaria Pleuronectiformes Pleuronectoidei Pleuronectidae Pseudopleuronectes
Pseudopleuronectes americanus (Winter flounder) (Pleuronectes americanus)
21
ice binding
82
Antifreeze protein B, HPLC8
None
8265
extracellular space
homoiothermy, response to freezing
3769927
21
24:44
RPDPAAKAAPAAAAVPAAAAP
PSQ01995
FD00516
Pesticidal crystal protein Cry9Aa
Q99031
Bacteria Firmicutes Bacilli Bacillales Bacillaceae Bacillus Bacillus cereus group
Bacillus thuringiensis subsp
23
signaling receptor binding, toxin activity
1156
130 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryIXA(a)
cry9Aa
29338
None
pathogenesis, sporulation resulting in formation of a cellular spore
1660003
23
1:23
MNQNKHGIIGASNCGCASDDVAK
PSQ01996
FD00312
Mannan endo-1
Q99036
Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Sordariomycetes Hypocreomycetidae Hypocreales Hypocreaceae Trichoderma
Hypocrea jecorina (strain ATCC 56765 , (Trichoderma reesei)
8
cellulose binding, disaccharide binding, mannan endo-1,4-beta-mannosidase activity
437
Beta-mannanase 5A, Beta-mannanase I, Endo-beta-1
man1
1344414
extracellular region
mannan catabolic process
7793911
8
20:27
AVLQPVPR
PSQ01997
FD00203
Proheparin-binding EGF-like growth factor
Q99075
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
43
epidermal growth factor receptor binding, growth factor activity, heparin binding
208
None
HBEGF
9606
cell surface, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, extracellular region, extracellular space, integral component of plasma membrane, plasma membrane
cell chemotaxis, epidermal growth factor receptor signaling pathway, ERBB2 signaling pathway, MAPK cascade, membrane organization, muscle organ development, negative regulation of elastin biosynthetic process, negative regulation of epidermal growth factor receptor signaling pathway, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell population proliferation, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of keratinocyte migration, positive regulation of protein kinase B signaling, positive regulation of smooth muscle cell proliferation, positive regulation of wound healing, regulation of cell motility, regulation of heart contraction, signal transduction, wound healing, spreading of epidermal cells
1556128
43
20:62
LVTGESLERLRRGLAAGTSNPDPPTVSTDQLLPLGGGRDRKVR
PSQ01998
FD00053
M-protease
Q99405
Bacteria Firmicutes Bacilli Bacillales Bacillaceae Alkalihalobacillus
Bacillus clausii (strain KSM-K16)
84
metal ion binding, serine-type endopeptidase activity
380
None
aprE
66692
extracellular region
None
7632397
84
28:111
AEEAKEKYLIGFNEQEAVSEFVEQIEANDDVAILSEEEEVEIELLHEFETIPVLSVELSPEDVDALELDPTISYIEEDAEVTTM
PSQ01999
FD00124
Sortilin
Q99523
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
44
enzyme binding, nerve growth factor binding, nerve growth factor receptor activity, neurotensin receptor activity, non-G protein-coupled, retromer complex binding
838
100 kDa NT receptor, Glycoprotein 95, Neurotensin receptor 3
SORT1
9606
cell surface, clathrin-coated pit, clathrin-coated vesicle, cytoplasmic vesicle, cytoplasmic vesicle membrane, cytosol, dendrite, early endosome, endoplasmic reticulum membrane, endosome membrane, Golgi apparatus, Golgi cisterna membrane, integral component of membrane, lysosomal membrane, lysosome, neuronal cell body, nuclear membrane, perinuclear region of cytoplasm, plasma membrane, trans-Golgi network transport vesicle
endocytosis, endosome to lysosome transport, endosome transport via multivesicular body sorting pathway, extrinsic apoptotic signaling pathway via death domain receptors, G protein-coupled receptor signaling pathway, glucose import, Golgi to endosome transport, Golgi to lysosome transport, multicellular organism development, myotube differentiation, negative regulation of fat cell differentiation, negative regulation of lipoprotein lipase activity, neuropeptide signaling pathway, neurotrophin TRK receptor signaling pathway, ossification, plasma membrane to endosome transport, positive regulation of epithelial cell apoptotic process, post-Golgi vesicle-mediated transport, protein targeting to lysosome, regulation of gene expression, response to insulin, vesicle organization
9756851
44
34:77
QDRLDAPPPPAAPLPRWSGPIGVSWGLRAAAAGGAFPRGGRWRR
PSQ02000
FD00219
Matrix metalloproteinase-19
Q99542
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
79
metalloendopeptidase activity, zinc ion binding
508
Matrix metalloproteinase RASI, Matrix metalloproteinase-18
MMP19
9606
extracellular matrix, extracellular region, extracellular space
angiogenesis, cell differentiation, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, luteolysis, ovarian follicle development, ovulation from ovarian follicle, proteolysis, response to cAMP, response to hormone
10809722
79
19:97
RVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLK