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Details of family id : FD00569

Family ID FD00569
Protein Name 72 kDa type IV collagenase
UniProt ID Q90611
Prosequence Length Range (aa) 80
Preproprotein Length Range(aa) 663
Preproprotein pI Range 5.27
Preproprotein Molecular Weight Range (D) 74941.27
Prosequence pI Range (D) 8.48
Prosequence Molecular Weight Range 8981.34
Domains cd00094 : pfam00413 : smart00059 : smart00059 : smart00059
Organisms Gallus gallus (Chicken)
Functions metalloendopeptidase activity; zinc ion binding
Cellular Localization basement membrane; collagen-containing extracellular matrix; extracellular space; plasma membrane; sarcomere
Processes blood vessel maturation; bone trabecula formation; cellular response to amino acid stimulus; cellular response to insulin-like growth factor stimulus; cellular response to reactive oxygen species; cellular response to UV-A; collagen catabolic process; endodermal cell differentiation; extracellular matrix organization; face morphogenesis; intramembranous ossification; negative regulation of cartilage condensation; negative regulation of cartilage development; negative regulation of focal adhesion assembly; negative regulation of protein phosphorylation; positive regulation of vascular associated smooth muscle cell proliferation; regulation of MAPK cascade; response to amyloid-beta; response to hypoxia; tissue remodeling
Common Name type IV collagenase