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Details of family id : FD00050

Family ID FD00050
Protein Name Interleukin-36 gamma; Interleukin-37; Interleukin-36 alpha; Interleukin-36 beta
UniProt ID Q9NZH8 Q9NZH6 Q9JLA2 Q8R460 Q9D6Z6
Prosequence Length Range (aa) 7-45
Preproprotein Length Range(aa) 160-218
Preproprotein pI Range 5.02-8.99
Preproprotein Molecular Weight Range (D) 18014.87-24126.49
Prosequence pI Range (D) 3.84-8.54
Prosequence Molecular Weight Range 891.05-4844.36
Domains cl00094
Organisms Homo sapiens (Human); Mus musculus (Mouse)
Functions cytokine activity; interleukin-1 receptor binding
Cellular Localization cytoplasm; extracellular region; extracellular space; cytosol; intracellular membrane-bounded organelle; nucleoplasm
Processes cell-cell signaling; cellular response to lipopolysaccharide; cytokine-mediated signaling pathway; inflammatory response; inflammatory response to antigenic stimulus; innate immune response; positive regulation of gene expression; cellular response to cytokine stimulus; immune response; negative regulation of interleukin-6 production; negative regulation of tumor necrosis factor production; regulation of inflammatory response; positive regulation of cytokine production; positive regulation of interleukin-6 production; negative regulation of myoblast differentiation; negative regulation of myoblast fusion; positive regulation of T cell differentiation
Common Name Interleukin