Details of family id : FD00082
Family ID |
FD00082 |
Protein Name |
Cathepsin B; Cathepsin B-like protease 3 |
UniProt ID |
P83205
P07858
Q94K85
P00787
|
Prosequence Length Range (aa) |
17-76
|
Preproprotein Length Range(aa) |
335-360 |
Preproprotein pI Range |
5.36-5.88 |
Preproprotein Molecular Weight Range (D) |
36725.4-39417.61 |
Prosequence pI Range (D) |
4.21-9.65 |
Prosequence Molecular Weight Range |
1789.96-8406.72 |
Domains |
cd02620 : pfam08127 |
Organisms |
Ovis aries (Sheep); Homo sapiens (Human); Arabidopsis thaliana (Mouse-ear cress); Rattus norvegicus (Rat) |
Functions |
cysteine-type endopeptidase activity; endopeptidase activity; collagen binding; cysteine-type peptidase activity; peptidase activity; proteoglycan binding; kininogen binding; peptide binding; protein self-association; protein-containing complex binding |
Cellular Localization |
apical plasma membrane; external side of plasma membrane; extracellular space; lysosome; melanosome; collagen-containing extracellular matrix; endolysosome lumen; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; intracellular anatomical structure; perinuclear region of cytoplasm; cytosol; secretory vesicle; vacuole; cell surface; cytoplasm; mitochondrion; sarcolemma |
Processes |
decidualization; proteolysis involved in cellular protein catabolic process; regulation of catalytic activity; thyroid hormone generation; viral entry into host cell; cellular response to thyroid hormone stimulus; collagen catabolic process; epithelial cell differentiation; neutrophil degranulation; proteolysis; regulation of apoptotic process; toll-like receptor signaling pathway; defense response; autophagy; cellular response to mechanical stimulus; negative regulation of cell death; response to amine; response to cytokine; response to ethanol; response to glucose; response to interleukin-4; response to mechanical stimulus; response to organic cyclic compound; response to peptide hormone; response to wounding; skeletal muscle tissue development; spermatogenesis |
Common Name |
Cathepsin B; Cathepsin B like protease |