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Details of family id : FD00082

Family ID FD00082
Protein Name Cathepsin B; Cathepsin B-like protease 3
UniProt ID P83205 P07858 Q94K85 P00787
Prosequence Length Range (aa) 17-76
Preproprotein Length Range(aa) 335-360
Preproprotein pI Range 5.36-5.88
Preproprotein Molecular Weight Range (D) 36725.4-39417.61
Prosequence pI Range (D) 4.21-9.65
Prosequence Molecular Weight Range 1789.96-8406.72
Domains cd02620 : pfam08127
Organisms Ovis aries (Sheep); Homo sapiens (Human); Arabidopsis thaliana (Mouse-ear cress); Rattus norvegicus (Rat)
Functions cysteine-type endopeptidase activity; endopeptidase activity; collagen binding; cysteine-type peptidase activity; peptidase activity; proteoglycan binding; kininogen binding; peptide binding; protein self-association; protein-containing complex binding
Cellular Localization apical plasma membrane; external side of plasma membrane; extracellular space; lysosome; melanosome; collagen-containing extracellular matrix; endolysosome lumen; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; intracellular anatomical structure; perinuclear region of cytoplasm; cytosol; secretory vesicle; vacuole; cell surface; cytoplasm; mitochondrion; sarcolemma
Processes decidualization; proteolysis involved in cellular protein catabolic process; regulation of catalytic activity; thyroid hormone generation; viral entry into host cell; cellular response to thyroid hormone stimulus; collagen catabolic process; epithelial cell differentiation; neutrophil degranulation; proteolysis; regulation of apoptotic process; toll-like receptor signaling pathway; defense response; autophagy; cellular response to mechanical stimulus; negative regulation of cell death; response to amine; response to cytokine; response to ethanol; response to glucose; response to interleukin-4; response to mechanical stimulus; response to organic cyclic compound; response to peptide hormone; response to wounding; skeletal muscle tissue development; spermatogenesis
Common Name Cathepsin B; Cathepsin B like protease