Details of family id : FD00010
| Family ID |
FD00010 |
| Protein Name |
Acidic phospholipase A2 CM-II ; Phospholipase A2 MALT0035C ; Basic phospholipase A2 beta-bungarotoxin A1 chain; Acidic phospholipase A2 beta-bungarotoxin A3 chain; Basic phospholipase A2 2; Acidic phospholipase A2 1; Neutral phospholipase A2 muscarinic inhibitor; Acidic phospholipase A2 homolog textilotoxin C chain; Acidic phospholipase A2 2; Phospholipase A2; Acidic phospholipase A2; Phospholipase A2 homolog mojave toxin acidic chain; Basic phospholipase A2 textilotoxin A chain; Basic phospholipase A2 beta-bungarotoxin A2 chain; Basic phospholipase A2 notechis 11 |
| UniProt ID |
P00596
F5CPF1
Q7T1R0
P00617
P00619
Q90WA8
Q9W7J4
P00598
Q92084
P80966
P30811
P00597
P00594
P00611
P04055
P00606
P18998
P23026
P00618
P08873
P04054
|
| Prosequence Length Range (aa) |
6-8
|
| Preproprotein Length Range(aa) |
132-154 |
| Preproprotein pI Range |
4.33-8.91 |
| Preproprotein Molecular Weight Range (D) |
14694.4-16844.05 |
| Prosequence pI Range (D) |
3.8-9.8 |
| Prosequence Molecular Weight Range |
637.78-1004.15 |
| Domains |
smart00085 |
| Organisms |
Naja kaouthia (Monocled cobra) (Naja siamensis); Micrurus altirostris (Uruguayan coral snake) (Elaps altirostris); Bungarus flaviceps flaviceps (Red-headed krait); Bungarus multicinctus (Many-banded krait); Bungarus fasciatus (Banded krait) (Pseudoboa fasciata); Pseudonaja textilis (Eastern brown snake); Naja atra (Chinese cobra); Naja sputatrix (Malayan spitting cobra) (Naja naja sputatrix); Ophiophagus hannah (King cobra) (Naja hannah); Equus caballus (Horse); Laticauda semifasciata (Black-banded sea krait) (Pseudolaticauda, semifasciata); Rattus norvegicus (Rat); Crotalus scutulatus scutulatus (Mojave rattlesnake); Notechis scutatus scutatus (Mainland tiger snake) (Common tiger snake); Homo sapiens (Human) |
| Functions |
calcium ion binding; phospholipase A2 activity; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine); phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine); toxin activity; bile acid binding; calcium-dependent phospholipase A2 activity; signaling receptor binding |
| Cellular Localization |
extracellular region; cell surface; extracellular space; secretory granule |
| Processes |
arachidonic acid secretion; lipid catabolic process; phospholipid metabolic process; fatty acid biosynthetic process; phosphatidylglycerol metabolic process; positive regulation of fibroblast proliferation; positive regulation of glomerular visceral epithelial cell apoptotic process; antibacterial humoral response; antimicrobial humoral immune response mediated by antimicrobial peptide; cellular response to insulin stimulus; defense response to Gram-positive bacterium; innate immune response in mucosa; phosphatidylcholine metabolic process; positive regulation of cell population proliferation; regulation of glucose import; actin filament organization; activation of MAPK activity; activation of phospholipase A2 activity; intracellular signal transduction; leukotriene biosynthetic process; neutrophil chemotaxis; neutrophil mediated immunity; phosphatidic acid biosynthetic process; phosphatidylcholine acyl-chain remodeling; phosphatidylethanolamine acyl-chain remodeling; phosphatidylglycerol acyl-chain remodeling; phosphatidylinositol acyl-chain remodeling; phosphatidylserine acyl-chain remodeling; positive regulation of calcium ion transport into cytosol; positive regulation of immune response; positive regulation of interleukin-8 production; positive regulation of NF-kappaB transcription factor activity; positive regulation of protein secretion; positive regulation of transcription by RNA polymerase II; signal transduction |
| Common Name |
phospholipase; Phospholipase |
