PSQ01651
FD00585
Pappalysin-1
Q13219
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
59
metalloendopeptidase activity, metallopeptidase activity, zinc ion binding
1627
Insulin-like growth factor-dependent IGF-binding protein 4 protease, Pregnancy-associated plasma protein A
PAPPA
9606
extracellular region, extracellular space
cellular protein metabolic process, female pregnancy, response to follicle-stimulating hormone, response to glucocorticoid
7508748, 7685339
59
23:81
ERPRRARRDPRAGRPPRPAAGPATCATRAARGRRASPPPPPPPGGAWEAVRVPRRRQQR
PSQ01652
FD00530
Apolipoprotein F
Q13790
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
129
cholesterol binding, lipid transporter activity, signaling receptor binding
326
Lipid transfer inhibitor protein
APOF
9606
extracellular space, high-density lipoprotein particle, low-density lipoprotein particle
cholesterol metabolic process, lipid metabolic process, lipid transport
8093033, 9880564
129
36:164
ATSYGKQTNVLMHFPLSLESQTPSSDPLSCQFLHPKSLPGFSHMAPLPKFLVSLALRNALEEAGCQADVWALQLQLYRQGGVNATQVLIQHLRGLQKGRSTERNVSVEALASALQLLAREQQSTGRVGR
PSQ01653
FD00197
Ectonucleotide pyrophosphatase
Q13822
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
8
alkylglycerophosphoethanolamine phosphodiesterase activity, calcium ion binding, hydrolase activity, lysophospholipase activity, nucleic acid binding, nucleotide diphosphatase activity, phosphodiesterase I activity, polysaccharide binding, scavenger receptor activity, transcription factor binding, zinc ion binding
863
Autotaxin , Extracellular lysophospholipase D
ENPP2
9606
extracellular space, plasma membrane
cell motility, chemotaxis, immune response, phosphatidylcholine catabolic process, phospholipid catabolic process, positive regulation of epithelial cell migration, positive regulation of lamellipodium morphogenesis, positive regulation of peptidyl-tyrosine phosphorylation, regulation of angiogenesis, regulation of cell migration, sphingolipid catabolic process
12176993, 18175805
8
28:35
FTAHRIKR
PSQ01654
FD00208
Caspase-8
Q14790
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
216, 10
cysteine-type endopeptidase activity, cysteine-type endopeptidase activity involved in apoptotic process, cysteine-type endopeptidase activity involved in apoptotic signaling pathway, cysteine-type endopeptidase activity involved in execution phase of apoptosis, cysteine-type peptidase activity, death effector domain binding, death receptor binding, identical protein binding, peptidase activity, protein-containing complex binding, scaffold protein binding, tumor necrosis factor receptor binding, ubiquitin protein ligase binding
480
Apoptotic cysteine protease, Apoptotic protease Mch-5 , CAP4, FADD-homologous ICE, FADD-like ICE , ICE-like apoptotic protease 5, MORT1-associated ced-3 homolog
CASP8
9606
CD95 death-inducing signaling complex, cell body, cytoplasm, cytoskeleton, cytosol, death-inducing signaling complex, membrane raft, mitochondrial outer membrane, mitochondrion, neuron projection, nucleoplasm, protein-containing complex, ripoptosome
activation of cysteine-type endopeptidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, angiogenesis, apoptotic process, apoptotic signaling pathway, B cell activation, cell surface receptor signaling pathway, cellular response to mechanical stimulus, cellular response to organic cyclic compound, death-inducing signaling complex assembly, execution phase of apoptosis, extrinsic apoptotic signaling pathway, extrinsic apoptotic signaling pathway via death domain receptors, heart development, macrophage differentiation, modulation by virus of host cellular process, natural killer cell activation, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, negative regulation of I-kappaB kinase/NF-kappaB signaling, negative regulation of necroptotic process, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of apoptotic process, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of interleukin-1 beta production, positive regulation of macrophage differentiation, positive regulation of neuron death, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of proteolysis, proteolysis, proteolysis involved in cellular protein catabolic process, pyroptosis, regulation of cytokine production, regulation of extrinsic apoptotic signaling pathway via death domain receptors, regulation of innate immune response, regulation of necroptotic process, regulation of tumor necrosis factor-mediated signaling pathway, response to antibiotic, response to cobalt ion, response to cold, response to estradiol, response to ethanol, response to lipopolysaccharide, response to tumor necrosis factor, self proteolysis, suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process, syncytiotrophoblast cell differentiation involved in labyrinthine layer development, T cell activation, toll-like receptor 3 signaling pathway, TRAIL-activated apoptotic signaling pathway, TRIF-dependent toll-like receptor signaling pathway
8962078, 9184224,;8962078, 9184224
226
1:216, 375:384
MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISDSPREQD, SEEQPYLEMD
PSQ01655
FD00134
Unique cartilage matrix-associated protein
Q14BU0
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus
Mus musculus (Mouse)
37
BMP binding
138
Upper zone of growth plate and cartilage matrix associated protein
Ucma
10090
aggresome, cytoplasm, cytoskeleton, extracellular matrix, extracellular region, extracellular space, Golgi apparatus, perinuclear region of cytoplasm
embryonic skeletal system development, negative regulation of biomineralization, negative regulation of osteoblast differentiation, negative regulation of SMAD protein signal transduction
18156182
37
28:64
SVGSRQAAAEGVQEGVKQKIFMQESDASNFLKRRGKR
PSQ01656
FD00080
Guanylate cyclase activator 2B
Q16661
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
62
calcium sensitive guanylate cyclase activator activity, guanylate cyclase activator activity
119
None
GUCA2B
9606
extracellular exosome, extracellular region
cGMP-mediated signaling, digestion, excretion
7589507
62
27:88
VYIQYQGFRVQLESMKKLSDLEAQWAPSPRLQAQSLLPAVCHHPALPQDLQPVCASQEASSI
PSQ01657
FD00279
Meprin A subunit beta
Q16820
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
39
identical protein binding, metalloendopeptidase activity, zinc ion binding
701
Endopeptidase-2, Meprin B, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta, PABA peptide hydrolase, PPH beta
MEP1B
9606
extracellular region, integral component of plasma membrane, meprin A complex
inflammatory response, toxin transport
8262185, 9288916
39
23:61
TPENFDVDGGMDQDIFDINEGLGLDLFEGDIRLDRAQIR
PSQ01658
FND00005
Phylloseptin-Az4
Q17UY9
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Hylidae Phyllomedusinae Pithecopus
Pithecopus azureus (Orange-legged monkey tree frog) (Phyllomedusa azurea)
22
None
60
Phylloseptin-12
psn12
2034991
extracellular region
defense response to bacterium
17553595
22
14:35
EEEKRETEEEENDQEEDDKSEE
PSQ01659
FD00085
Aspartic protease 10
Q18020
Eukaryota Metazoa Ecdysozoa Nematoda Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis
Caenorhabditis elegans
289
aspartic-type endopeptidase activity
428
Heme transporter hrg-7 , Heme-responsive gene 7 protein
hrg-7
6239
extracellular region, lysosome
cell death
28581477
289
17:305
EVHQFNIGYRPNMRQRMNAKGKLAEYEKERNELLSKKSLQLASSSSPVIDYEDMAYMVQISLGSPAQNFVLFIDSGSSNLWVPDITCAGGKDATCGSYCKSTPYDACLTFCQEECCTKTVEGVKVLSTTDACQSKHRFNSSLSSSYVTNGQKFDMTYNTGEVKGFFGVDTFCFTNTSVCATGQVFGQATTIGEAFAKQPEDGIIGLGWPALAVNQQTPPLFNLMNQGKLDQPYFVVYLANIGPTSQINGGAFTVGGLDTTHCSSNVDWVPLSTQTFWQFKLGGVSSGSY
PSQ01660
FND00200
FMRFamide-like neuropeptides 27
Q18184
Eukaryota Metazoa Ecdysozoa Nematoda Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis
Caenorhabditis elegans
12, 26
None
89
None
flp-27
6239
extracellular region
neuropeptide signaling pathway
19456328;19456328
38
24:35, 64:89
QPIDEERPIFME, SSSPDISLAEMRAIYGGDQSNIFNFK
PSQ01661
FD00273
Neuronal immunoglobulin domain-containing protein rig-3
Q18806
Eukaryota Metazoa Ecdysozoa Nematoda Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis
Caenorhabditis elegans
21
cell-cell adhesion mediator activity
487
None
rig-3
6239
anchored component of membrane, axon, plasma membrane, synapse
axon guidance, dendrite self-avoidance, homophilic cell adhesion via plasma membrane adhesion molecules
21745641
21
467:487
SASDSKFPLALATLFFVCLFI
PSQ01662
FD00048
Osteocalcin 1
Q1EG28
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Neoteleostei Acanthomorphata Carangaria Pleuronectiformes Pleuronectoidei Soleidae Solea
Solea senegalensis (Senegalese sole)
29
calcium ion binding
95
Bone Gla protein , Gamma-carboxyglutamic acid-containing protein
bglapBGP
28829
extracellular region
biomineral tissue development, bone development, regulation of cellular response to insulin stimulus, response to vitamin K
24185858
29
22:50
SFSSQPAVDTPAQEGLFVEQEQASSVVRQ
PSQ01663
FD00002
Dermaseptin-H5
Q1EJP4
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Hylidae Phyllomedusinae Pithecopus
Pithecopus azureus (Orange-legged monkey tree frog) (Phyllomedusa azurea)
21
None
68
Dermaseptin-like peptide 5
dpp-H5
2034991
extracellular region
defense response to bacterium
17553595
21
18:38
EEEKRENEDEEKQEDDEQSEM
PSQ01664
FD00002
Dermaseptin-H4
Q1EJP5
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Hylidae Phyllomedusinae Pithecopus
Pithecopus azureus (Orange-legged monkey tree frog) (Phyllomedusa azurea)
21
None
73
Dermaseptin-like peptide 4
dpp-H4
2034991
extracellular region
defense response to bacterium
17553595
21
23:43
EEEKRENEDEAKQEDDEQSEM
PSQ01665
FD00059
M-zodatoxin-Lt1a
Q1ELT9
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Entelegynae incertae sedis Zodariidae Lachesana
Lachesana tarabaevi (Spider)
40
toxin activity
88
Latarcin-1
None
379576
extracellular region
defense response to bacterium, defense response to fungus, hemolysis in other organism
16735513
40
23:62
YDVNEELENELDDLSDAAWLAKAAEDLQALDDFEESEESR
PSQ01666
FD00059
M-zodatoxin-Lt2a
Q1ELU1
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Entelegynae incertae sedis Zodariidae Lachesana
Lachesana tarabaevi (Spider)
36
toxin activity
84
Latarcin-2a
None
379576
extracellular region
defense response to bacterium, defense response to fungus, hemolysis in other organism
16735513
36
23:58
YEVNEELENELDDLDDAAWLAVAEELQGLEDFEESR
PSQ01667
FND00059
M-zodatoxin-Lt3b
Q1ELU2
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Entelegynae incertae sedis Zodariidae Lachesana
Lachesana tarabaevi (Spider)
39
toxin activity
82
Latarcin-3b
None
379576
extracellular region
defense response to bacterium, defense response to fungus, killing of cells of other organism
16735513
39
23:61
YPVEDLEDDELTELEAEALLEDLLEDLELEDLDYNEEAR
PSQ01668
FND00059
M-zodatoxin-Lt3a
Q1ELU3
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Entelegynae incertae sedis Zodariidae Lachesana
Lachesana tarabaevi (Spider)
39
toxin activity
82
La47, Latarcin-3a
None
379576
extracellular region, membrane, other organism cell membrane
defense response to bacterium, defense response to fungus, killing of cells of other organism
16735513, 23093034
39
23:61
YPVEDLEDDELTELEAEALLEDLLEDLELEDLDYNEEAR
PSQ01669
FND00231
M-zodatoxin-Lt4b
Q1ELU4
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Entelegynae incertae sedis Zodariidae Lachesana
Lachesana tarabaevi (Spider)
21, 9, 9, 9, 8
toxin activity
180
None
None
379576
extracellular region
defense response to bacterium, defense response to fungus, killing of cells of other organism
16735513;27287558;27287558;27287558;27287558
56
23:43, 63:71, 91:99, 119:127, 147:154
EEEGYDVSEEIQAEELEEAAR, REDSEDAGR, REDTEEAGR, REDSEEAGR, REDTEEAR
PSQ01670
FD00059
M-zodatoxin-Lt4a
Q1ELU5
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Entelegynae incertae sedis Zodariidae Lachesana
Lachesana tarabaevi (Spider)
9, 9, 9, 9, 8
toxin activity
207
None
None
379576
extracellular region
defense response to bacterium, defense response to fungus, killing of cells of other organism
27287558;27287558;27287558;27287558;27287558
44
63:71, 91:99, 119:127, 147:155, 175:182
REDSEEAGR, REDSEEAGR, REDSEEAGR, REDSEEAGR, REDTEEAR
PSQ01671
FD00059
M-zodatoxin-Lt5a
Q1ELU9
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Entelegynae incertae sedis Zodariidae Lachesana
Lachesana tarabaevi (Spider)
42
toxin activity
93
Latarcin-5
None
379576
extracellular region
defense response to bacterium, defense response to fungus, hemolysis in other organism
16735513
42
23:64
TETGYAVAETLEDNDLDELQAYLEEIAEASEMEDFSNIEEAR
PSQ01672
FND00004
Dermaseptin-S13
Q1EN11
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Hylidae Phyllomedusinae Phyllomedusa
Phyllomedusa sauvagei (Sauvage
23
None
73
None
None
8395
extracellular region, membrane, other organism cell membrane
defense response to bacterium, defense response to fungus, innate immune response, killing of cells of other organism
16401077
23
23:45
DEEKRENEDEENQEDDEQSEMRR
PSQ01673
FND00004
Dermaseptin-S12
Q1EN12
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Hylidae Phyllomedusinae Phyllomedusa
Phyllomedusa sauvagei (Sauvage
23
None
72
None
None
8395
extracellular region, membrane, other organism cell membrane
defense response to bacterium, defense response to fungus, innate immune response, killing of cells of other organism
16401077
23
22:44
EEEKRENEDEENQEDDEQSEMRR
PSQ01674
FD00002
Dermaseptin-S11
Q1EN13
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Hylidae Phyllomedusinae Phyllomedusa
Phyllomedusa sauvagei (Sauvage
23
None
75
None
None
8395
extracellular region, membrane, other organism cell membrane
defense response to bacterium, defense response to fungus, innate immune response, killing of cells of other organism
16401077
23
23:45
EEEKRENEDEEEQEDDEQSEEKR
PSQ01675
FND00016
Plasticin-S1
Q1EN14
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Hylidae Phyllomedusinae Phyllomedusa
Phyllomedusa sauvagei (Sauvage
23
None
70
Dermaseptin-S10
None
8395
extracellular region
None
16401077
23
23:45
EEEKREGENEKEQEDDNQSEEKR
PSQ01676
FND00004
Atypical cationic antimicrobial peptide
Q1EN15
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Hyloidea Hylidae Phyllomedusinae Phyllomedusa
Phyllomedusa sauvagei (Sauvage
23
None
69
Dermaseptin-S9
None
8395
extracellular region, membrane, other organism cell membrane
chemotaxis, defense response to bacterium, innate immune response
16401077
23
23:45
DEEKRENEDEENQEDDEQSEMRR
PSQ01677
FD00565
Monalysin
Q1I8U1
Bacteria Proteobacteria Gammaproteobacteria Pseudomonadales Pseudomonadaceae Pseudomonas
Pseudomonas entomophila (strain L48)
33
porin activity, toxin activity
271
beta-barrel pore-forming toxin
mnl
384676
extracellular region, host cell plasma membrane, pore complex
hemolysis in other organism, ion transport, pathogenesis, protein homooligomerization
21980286
33
1:33
MTIKEELGQPQSHSIELDEVSKEAASTRAALTS
PSQ01678
FD00149
Photosystem II protein D1
Q1KVU8
Eukaryota Viridiplantae Chlorophyta core chlorophytes Chlorophyceae Sphaeropleales Scenedesmaceae Tetradesmus
Tetradesmus obliquus (Green alga) (Acutodesmus obliquus)
9
chlorophyll binding, electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity, iron ion binding, oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor, oxygen evolving activity
360
Photosystem II Q(B) protein
psbA
3088
chloroplast thylakoid membrane, integral component of membrane, photosystem II
photosynthetic electron transport in photosystem II, protein-chromophore linkage, response to herbicide
9252339
9
345:353
SVEAPSVNA
PSQ01679
FND00104
FMRFamide-related peptides
Q1MX22
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Lepidoptera Glossata Ditrysia Bombycoidea Bombycidae Bombycinae Bombyx
Bombyx mori (Silk moth)
11, 47, 19, 33
None
180
Bommo-FMRFamide
RFa
7091
extracellular region
neuropeptide signaling pathway
16707581;16707581;16707581;16707581
110
22:32, 47:93, 113:131, 145:177
TPVRRSPDLEA, RSTLPVVPPAQPSFLQRYSAPQPAALTADDLMTFLRAYEEDYSSPVS, RSVDEENSGYQAETNTYPQ, RDNELSESNDEDRYEVESERTKRSVVDPCNDCA
PSQ01680
FD00013
Zinc metalloproteinase-disintegrin-like BjussuMP-1
Q1PHZ4
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Bothrops
Bothrops jararacussu (Jararacussu)
133
metal ion binding, metalloendopeptidase activity, toxin activity
547
BjussuMP-I, Snake venom metalloproteinase
None
8726
extracellular region
defense response to bacterium
17081786
133
1:133
EFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGRQITTYPPVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGETYLIEPLKLSDSEAHAVYKYENVEKEDEAPKMCGVTETNWEYEEPIKKASKLVVTA
PSQ01681
FD00223
Metalloprotease mig-17
Q20930
Eukaryota Metazoa Ecdysozoa Nematoda Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis
Caenorhabditis elegans
186
metal ion binding, metalloendopeptidase activity, metallopeptidase activity
509
Abnormal cell migration protein 17
mig-17
6239
basement membrane, extracellular space
gonad morphogenesis, protein autoprocessing, protein localization, regulation of cell migration, regulation of distal tip cell migration, zymogen activation
18637819
186
21:206
ARREKQQSNDISFVKRKVQDGLKFSRVIKYTNETIQGMKTNFNSNKTQELSLDVLVVADFLSYQAFLEMSNGDSHRAIHNLKEYLHALFEQTKIIYDGISFGNETLHMVFAGTWIATQERDCPLWISWAEEEEERVLNEEIRRLEEKERDLNSTFVDDTFFMNSTDSDNSSTDALISSDMPKKLRK
PSQ01682
FD00456
Lysosomal beta glucosidase
Q23892
Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia Dictyosteliales Dictyosteliaceae Dictyostelium
Dictyostelium discoideum (Slime mold)
45
beta-glucosidase activity, scopolin beta-glucosidase activity
821
None
gluA
44689
lysosome
glucan catabolic process
8288612
45
25:69
SSIRVSIVGGEEAEVIEKPRTFGNKRELKLEYSQIYPKKQLNQEN
PSQ01683
FD00012
Cathepsin L-like proteinase
Q24940
Eukaryota Metazoa Spiralia Lophotrochozoa Platyhelminthes Trematoda Digenea Plagiorchiida Echinostomata Echinostomatoidea Fasciolidae Fasciola
Fasciola hepatica (Liver fluke)
91
cysteine-type endopeptidase activity, endopeptidase activity
326
None
Cat-1
6192
extracellular region
proteolysis
8192668
91
16:106
SNDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILSHGVPYEANNR
PSQ01684
FD00472
Holotricin-2
Q25054
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Coleoptera Polyphaga Scarabaeiformia Scarabaeidae Melolonthinae Holotrichia
Holotrichia diomphalia (Korean black chafer)
40
None
127
None
None
33394
extracellular region
defense response to bacterium, innate immune response
8188641
40
16:55
AYVVPVYYEIYPEDATFDEADIEPQLSPAELHHGSIRERR
PSQ01685
FD00568
Delta-latroinsectotoxin-Lt1a
Q25338
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Araneoidea Theridiidae Latrodectus
Latrodectus tredecimguttatus (Mediterranean black widow spider), (Latrodectus mactans tredecimguttatus)
278
toxin activity
1214
Delta-latroinsectotoxin
None
6925
extracellular region, integral component of membrane, other organism cell membrane
exocytosis
8631785
278
28:305
RDEEDGEMTLEERQAQCKAIEYSNSVFGMIADVANDIGSIPVIGEVVGIVTAPIAIVSHITSAGLDIASTALDCDDIPFDEIKEILEERFNEIDRKLDKNTAALEEVSKLVSKTFVTVEKTRNEMNENFKLVLETIESKEIKSIVFKINDFKKFFEKERQRIKGLPKDRYVAKLLEQKGILGSLKEVREPSGNSLSSALNELLDKNNNYAIPKVVDDNKAFQALYALFYGTQTYAAVMFFLLEQHSYLADYYYQKGDDVNFNAEFNNVAIIFDDFKSS
PSQ01686
FND00132
APGW-amide-related neuropeptide
Q25461
Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Bivalvia Autobranchia Pteriomorphia Mytiloida Mytiloidea Mytilidae Mytilinae Mytilus
Mytilus edulis (Blue mussel)
26, 11, 11, 8, 15, 8, 35
None
196
None
None
6550
None
neuropeptide signaling pathway
8852595;8852595;8852595;8852595;8852595;8852595;8852595
114
23:48, 58:68, 78:88, 98:105, 115:129, 139:146, 162:196
SDESSERKKRDLDTIDDTNNDFLTAD, SFDDDILNNLD, SDMLFDSEEIE, SSSLYDDE, SSALLDDLSLYNSIV, SDTFKVDI, SGPNMCMDFQDEILQLYKLLNEAEKLHSECEALNI
PSQ01687
FD00003
Mu-conotoxin MrVIB
Q26443
Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Neogastropoda Conoidea Conidae Conus Conus
Conus marmoreus (Marble cone)
27
ion channel inhibitor activity, toxin activity
82
CGX-1002
None
42752
extracellular region
pathogenesis
7622492, 7727394
27
23:49
DDSNNGLANHFLKSRDEMEDPEASKLE
PSQ01688
FD00047
M-myrmeciitoxin-Mp2a
Q26464
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Hymenoptera Apocrita Aculeata Formicoidea Formicidae Myrmeciinae Myrmeciini Myrmecia
Myrmecia pilosula (Jack jumper ant) (Australian jumper ant)
22
toxin activity
75
Allergen Myr p II , DELTA-myrtoxin-Mp1a A chain , Pilosin-3 subunit a , Pilosulin-2
None
13618
extracellular region
defense response to bacterium, hemolysis in other organism
8605256
22
27:48
KALADPESDAVGFADAVGEADP
PSQ01689
FD00218
Microneme antigen
Q26539
Eukaryota Sar Alveolata Apicomplexa Conoidasida Coccidia Eucoccidiorida Eimeriorina Sarcocystidae Sarcocystis
Sarcocystis muris
69
carbohydrate binding
241
Lectin SML3
None
5813
cytoplasmic vesicle, extracellular region, microneme
cell adhesion, proteolysis
8801555
69
35:103
AADALSWSGGLIHSPAHRVNVMRSHHHEMGKELEQQHGAEEQQMQRDTKPAAFSNPPHLATGRGPSFVH
PSQ01690
FD00012
Cathepsin L
Q26636
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Diptera Brachycera Muscomorpha Oestroidea Sarcophagidae Sarcophaga Boettcherisca
Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)
104
cysteine-type endopeptidase activity
339
None
None
7386
lysosome
cell differentiation, multicellular organism development
8195162
104
18:121
ISPLDLIKEEWHTYKLQHRKNYANEVEERFRMKIFNENRHKIAKHNQLFAQGKVSYKLGLNKYADMLHHEFKETMNGYNHTLRQLMRERTGLVGATYIPPAHVT
PSQ01691
FD00213
Clotting factor B
Q27081
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Merostomata Xiphosura Limulidae Tachypleus
Tachypleus tridentatus (Japanese horseshoe crab)
21
endopeptidase activity, serine-type endopeptidase activity
400
Coagulation factor B
None
6853
extracellular region
hemolymph coagulation, protein processing
8407978
21
104:124
LPRLHISGCGKRKVKIDITTV
PSQ01692
FD00007
Chymotrypsin-1
Q27289
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Diptera Nematocera Culicoidea Culicidae Anophelinae Anopheles
Anopheles gambiae (African malaria mosquito)
15
serine-type endopeptidase activity
259
AnChym1
CHYM1
7165
extracellular region
digestion
11453997
15
18:32
AKVTKLVLDDNYVNR
PSQ01693
FD00073
Phenoloxidase subunit 1
Q27451
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Lepidoptera Glossata Ditrysia Bombycoidea Bombycidae Bombycinae Bombyx
Bombyx mori (Silk moth)
51
metal ion binding, monophenol monooxygenase activity
685
PO 1, Tyrosinase 1
None
7091
extracellular region
defense response, melanin biosynthetic process from tyrosine
7644494
51
1:51
MSDAKNNLLLFFDRPSEPCFMQKGEENAVFEIPDNYYPEKYQRVSNAIGNR
PSQ01694
FD00073
Phenoloxidase subunit 2
Q27452
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Lepidoptera Glossata Ditrysia Bombycoidea Bombycidae Bombycinae Bombyx
Bombyx mori (Silk moth)
51
metal ion binding, monophenol monooxygenase activity
693
PO 2, Tyrosinase 2
None
7091
extracellular region
defense response, melanin biosynthetic process from tyrosine
7644494
51
1:51
MADVFESLELLFDRPNEPLITPKGENNSVFQLTEQFLTEDYANNGIELNNR
PSQ01695
FD00159
Growth-blocking peptide
Q27913
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Lepidoptera Glossata Ditrysia Noctuoidea Noctuidae Hadeninae Mythimna
Mythimna separata (Oriental armyworm) (Pseudaletia separata)
98
cytokine activity, growth factor activity
145
None
None
271217
extracellular space
hemocyte migration, positive regulation of cell division, regulation of synaptic transmission, dopaminergic
12182821, 2022627, 8580912
98
23:120
KLKDLFGKIHDSVHGTADKVKEDLNSLFHPNDKNQQGNNDASSNIHFADSEENTDAAKKPDEVTPATTTTTTAAPAVPNAPSDNPTTLAPSTTTKDGR
PSQ01696
FD00004
Venom plasminogen activator LV-PA
Q27J47
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Lachesis
Lachesis muta muta (Bushmaster)
6
serine-type endopeptidase activity, toxin activity
258
LMUT0402S, Plasminogen activating proteinase, Snake venom serine protease
None
8753
extracellular region
regulation of blood pressure
10871053, 17034951
6
19:24
QKSSKL
PSQ01697
FD00037
Bradykinin-potentiating and C-type natriuretic peptides
Q27J49
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Lachesis
Lachesis muta muta (Bushmaster)
10, 7, 7, 28, 70
hormone activity, metalloendopeptidase inhibitor activity, toxin activity
240
BPP-CNP
None
8753
extracellular region
regulation of blood pressure, vasodilation
15876444;15876444;15876444;15876444, 16277978,;15876444, 16277978
122
24:33, 43:49, 76:82, 109:136, 148:217
KPVQQWSHKG, LVVQQWS, LVVQQWS, LLKPHESPAGGTTALREELSLGPEAALD, GSKAPAAPHRLPKSKGASATSAASRPMRDLRTDGKQARQNWGRMMNPDHHAVGGGGGGGGARRLKGLAKK
PSQ01698
FD00080
Guanylate cyclase activator 2B
Q28358
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Metatheria Didelphimorphia Didelphidae Didelphis
Didelphis virginiana (North American opossum) (Didelphis marsupialis, virginiana)
71
guanylate cyclase activator activity
109
None
GUCA2B
9267
extracellular region
None
7902563
71
24:94
VYIQYEGFQVKLDSVKKLDELLEQPRSFRHRMGTQRDPSVLCSDPALPSDLQPVCENSQAANIFRALRSIS
PSQ01699
FD00043
Pregnancy-associated glycoprotein 1
Q28755
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Caprinae Ovis
Ovis aries (Sheep)
38
aspartic-type endopeptidase activity
382
Inactive aspartic protease PAG-1, Pregnancy-associated glycoprotein 66d
None
9940
extracellular space
None
15460157
38
16:53
IVKIPLRRVKTMRNTLSGKKMLNSFLKEHAYRLSQISF
PSQ01700
FD00522
Acrosin-binding protein
Q29016
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Suina Suidae Sus
Sus scrofa (Pig)
244
None
540
Acrosin-binding protein, Proacrosin-binding protein sp32
ACRBP
9823
acrosomal membrane, acrosomal vesicle, extracellular region
acrosome assembly, fertilization, sperm capacitation
8144514
244
26:269
QDANSASTPGSPLSPTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYENHGLVPDGAVCSDLPYASWFESFCQFTQYRCSNHVYYAKRVRCSQPVSILSPNSLKEVDTSSEVPITTMTSPVSSHITATGRQVFQPWPERLNNNVEELLQSSLSLGGQEQGQEHKQEHKQEQGQEHKQDEGQEQEEQEEEQEEEGKQEEGQGTEESLEAMSGLQADSEPKFQSEFVSSNPFSFTPRVR