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Details of family id : FD00037

Family ID FD00037
Protein Name Natriuretic and helokinestatin peptides ; C-type natriuretic peptide 1; Bradykinin-potentiating and C-type natriuretic peptides; C-type natriuretic peptide
UniProt ID C6EVG7 P20968 Q27J49 P18104 Q6LEM5 P18145 P84715
Prosequence Length Range (aa) 7-89
Preproprotein Length Range(aa) 121-256
Preproprotein pI Range 7.71-11.15
Preproprotein Molecular Weight Range (D) 13148.18-26813.87
Prosequence pI Range (D) 4.44-12.01
Prosequence Molecular Weight Range 844.97-10262.45
Domains pfam00212
Organisms Heloderma suspectum cinctum (Banded Gila monster); Lithobates catesbeianus (American bullfrog) (Rana catesbeiana); Lachesis muta muta (Bushmaster); Sus scrofa (Pig); Bothrops jararaca (Jararaca) (Bothrops jajaraca); Anguilla japonica (Japanese eel); Ornithorhynchus anatinus (Duckbill platypus)
Functions hormone activity; toxin activity; metalloendopeptidase inhibitor activity; hormone receptor binding; signaling receptor binding; peptidyl-dipeptidase inhibitor activity; potassium channel activity; sodium channel activity
Cellular Localization extracellular region; protein-containing complex; cytosol
Processes regulation of blood pressure; cGMP biosynthetic process; growth plate cartilage chondrocyte differentiation; growth plate cartilage chondrocyte proliferation; receptor guanylyl cyclase signaling pathway; vasodilation; negative regulation of meiotic cell cycle; negative regulation of oocyte maturation; ossification; post-embryonic development; protein folding; regulation of multicellular organism growth; reproductive process; blood vessel diameter maintenance; negative regulation of protein kinase activity; envenomation resulting in induction of edema in other organism; positive regulation of mast cell degranulation in other organism; positive regulation of relaxation of uterine smooth muscle in other organism
Common Name Natriuretic and helokinestatin peptides; C-type natriuretic peptide; bradykinin potentiating and C-type natriuretic peptides