Details of family id : FD00012
| Family ID |
FD00012 |
| Protein Name |
Caricain; Cathepsin L; Cathepsin L-like proteinase; Chymopapain; Papain; Papaya proteinase 4; P34 probable thiol protease; Digestive cysteine proteinase 1; Procathepsin L; Crustapain; Cysteine proteinase ACP2; Actinidain ; Cysteine proteinase ACP1; Cysteine proteinase 1; Procathepsin L ; Actinidain; Ananain |
| UniProt ID |
P10056
Q26636
Q24940
P14080
P00784
P05994
P22895
P13277
P07154
Q86GF7
P36185
A5HII1
P36184
Q01957
P07711
P00785
P80884
|
| Prosequence Length Range (aa) |
79-181
|
| Preproprotein Length Range(aa) |
308-380 |
| Preproprotein pI Range |
4.8-8.62 |
| Preproprotein Molecular Weight Range (D) |
33851.14-42793.82 |
| Prosequence pI Range (D) |
4.15-9.74 |
| Prosequence Molecular Weight Range |
9072.2-19659.81 |
| Domains |
pfam00112 : smart00848 |
| Organisms |
Carica papaya (Papaya); Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina); Fasciola hepatica (Liver fluke); Glycine max (Soybean) (Glycine hispida); Homarus americanus (American lobster); Rattus norvegicus (Rat); Pandalus borealis (Northern red shrimp); Entamoeba histolytica; Actinidia deliciosa (Kiwi); Homo sapiens (Human); Actinidia chinensis var; Ananas comosus (Pineapple) (Ananas ananas) |
| Functions |
cysteine-type peptidase activity; cysteine-type endopeptidase activity; endopeptidase activity; serpin family protein binding; aminopeptidase activity; collagen binding; cysteine-type carboxypeptidase activity; fibronectin binding; histone binding; kininogen binding; peptide binding; protein-containing complex binding; proteoglycan binding |
| Cellular Localization |
lysosome; extracellular region; extracellular space; apical plasma membrane; chromaffin granule; cytoplasm; cytoplasmic vesicle; external side of plasma membrane; microvillus; multivesicular body; neuron projection; nucleolus; nucleus; perikaryon; plasma membrane; vacuole; collagen-containing extracellular matrix; endocytic vesicle lumen; endolysosome lumen; extracellular exosome; Golgi apparatus; intracellular membrane-bounded organelle; lysosomal lumen |
| Processes |
cell differentiation; multicellular organism development; proteolysis; proteolysis involved in cellular protein catabolic process; adaptive immune response; antigen processing and presentation of peptide antigen; autophagic cell death; CD4-positive; alpha-beta T cell lineage commitment; cell communication; cellular response to starvation; cellular response to thyroid hormone stimulus; collagen catabolic process; decidualization; elastin catabolic process; enkephalin processing; fusion of virus membrane with host endosome membrane; fusion of virus membrane with host plasma membrane; hair follicle morphogenesis; immune response; male gonad development; multicellular organism aging; negative regulation of keratinocyte proliferation; nerve development; protein autoprocessing; protein processing; receptor-mediated endocytosis of virus by host cell; regulation of actin cytoskeleton reorganization; response to glucocorticoid; response to glucose; response to gonadotropin; response to odorant; response to organic cyclic compound; Sertoli cell differentiation; spermatogenesis; thyroid hormone generation; viral entry into host cell; zymogen activation; digestion; protein catabolic process; antigen processing and presentation; antigen processing and presentation of exogenous peptide antigen via MHC class II; extracellular matrix disassembly; macrophage apoptotic process; regulation of keratinocyte differentiation; toll-like receptor signaling pathway |
| Common Name |
Caricain; Cathepsin; Chymopapain; Papain; papaya proteinase; probable thiol protease; Digestive cysteine proteinase; Procathepsin; Crustapain; cysteine proteinase; Actinidain; Ananain |
