Details of PSQ02107
| ProSeqID |
PSQ02107 |
| Family |
FD00415 |
| Protein Name |
Apoptosis-inducing factor 1 |
| UniProt ID |
Q9Z0X1
|
| Taxonomy |
Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Mus-Mus |
| Organisms |
Mus musculus (Mouse) |
| Prosequence Length (aa) |
47 |
| Functions |
DNA binding, electron-transferring-flavoprotein dehydrogenase activity, FAD binding, NAD(P)H oxidase H2O2-forming activity, NADH dehydrogenase activity, oxidoreductase activity, acting on NAD(P)H, protein dimerization activity |
| Preproprotein Length (aa) |
612 |
| Alt Name |
Programmed cell death protein 8 |
| Gene Name |
Aifm1 |
| NCBI ID |
10090 |
| Cellular Localization |
cytoplasm, cytosol, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial outer membrane, mitochondrion, nucleus, perinuclear region of cytoplasm |
| Processes |
activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic mitochondrial changes, apoptotic process, cellular response to aldosterone, cellular response to estradiol stimulus, cellular response to hydrogen peroxide, cellular response to nitric oxide, cellular response to oxygen-glucose deprivation, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, mitochondrial respiratory chain complex assembly, mitochondrial respiratory chain complex I assembly, neuron apoptotic process, neuron differentiation, positive regulation of apoptotic process, positive regulation of cell death, positive regulation of neuron apoptotic process, protein import into mitochondrial intermembrane space, regulation of apoptotic DNA fragmentation, response to ischemia, response to L-glutamate, response to oxidative stress, response to toxic substance |
| PubMed |
9989411
|
| Total Prosequence Length (aa) |
47 |
| Prosequence Location |
55:101 |
| Prosequence Sequence |
SSGSSGGKMDNSVLVLIVGLSTIGAGAYAYKTIKEDQKRYNERVMGL |
| Preproprotein Sequence |
MFRCGGLAGAFKQKLVPLVRTVYVQRPKQRNRLPGNLFQQWRVPLELQMARQMASSGSSGGKMDNSVLVLIVGLSTIGAGAYAYKTIKEDQKRYNERVMGLGLSPEEKQRRAIASATEGGSVPQIRAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLQFRQWNGKERSIYFQPPSFYVSAQDLPNIENGGVAVLTGKKVVHLDVRGNMVKLNDGSQITFEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRALEKISREVKSITVIGGGFLGSELACALGRKSQASGIEVIQLFPEKGNMGKILPQYLSNWTMEKVKREGVKVMPNAIVQSVGVSGGRLLIKLKDGRKVETDHIVTAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSAPAVPQVPVEGEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED |
