Details of family id : FD00415
| Family ID |
FD00415 |
| Protein Name |
Apoptosis-inducing factor 1 |
| UniProt ID |
Q9Z0X1
|
| Prosequence Length Range (aa) |
47
|
| Preproprotein Length Range(aa) |
612 |
| Preproprotein pI Range |
9.23 |
| Preproprotein Molecular Weight Range (D) |
66765.49 |
| Prosequence pI Range (D) |
9.22 |
| Prosequence Molecular Weight Range |
4965.67 |
| Domains |
pfam07992 : pfam14721 |
| Organisms |
Mus musculus (Mouse) |
| Functions |
DNA binding; electron-transferring-flavoprotein dehydrogenase activity; FAD binding; NAD(P)H oxidase H2O2-forming activity; NADH dehydrogenase activity; oxidoreductase activity; acting on NAD(P)H; protein dimerization activity |
| Cellular Localization |
cytoplasm; cytosol; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial outer membrane; mitochondrion; nucleus; perinuclear region of cytoplasm |
| Processes |
activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic mitochondrial changes; apoptotic process; cellular response to aldosterone; cellular response to estradiol stimulus; cellular response to hydrogen peroxide; cellular response to nitric oxide; cellular response to oxygen-glucose deprivation; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; mitochondrial respiratory chain complex assembly; mitochondrial respiratory chain complex I assembly; neuron apoptotic process; neuron differentiation; positive regulation of apoptotic process; positive regulation of cell death; positive regulation of neuron apoptotic process; protein import into mitochondrial intermembrane space; regulation of apoptotic DNA fragmentation; response to ischemia; response to L-glutamate; response to oxidative stress; response to toxic substance |
| Common Name |
Apoptosis inducing factor |
