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Details of PSQ02048

ProSeqID PSQ02048
Family FD00050
Protein Name Interleukin-37
UniProt ID Q9NZH6
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Primates-Haplorrhini-Catarrhini-Hominidae-Homo
Organisms Homo sapiens (Human)
Prosequence Length (aa) 45
Functions cytokine activity, interleukin-1 receptor binding
Preproprotein Length (aa) 218
Alt Name FIL1 zeta, IL-1X, Interleukin-1 family member 7, Interleukin-1 homolog 4, Interleukin-1 zeta, Interleukin-1-related protein, Interleukin-23
Gene Name IL37
NCBI ID 9606
Cellular Localization cytosol, extracellular region, extracellular space, intracellular membrane-bounded organelle, nucleoplasm
Processes cellular response to cytokine stimulus, cellular response to lipopolysaccharide, cytokine-mediated signaling pathway, immune response, inflammatory response, inflammatory response to antigenic stimulus, negative regulation of interleukin-6 production, negative regulation of tumor necrosis factor production, positive regulation of gene expression, regulation of inflammatory response
PubMed 11145836
Total Prosequence Length (aa) 45
Prosequence Location 1:45
Prosequence Sequence MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMNF
Preproprotein Sequence MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMNFVHTSPKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD