Details of PSQ01828
| ProSeqID |
PSQ01828 |
| Family |
FD00118 |
| Protein Name |
Alpha-2-antiplasmin |
| UniProt ID |
Q61247
|
| Taxonomy |
Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Mus-Mus |
| Organisms |
Mus musculus (Mouse) |
| Prosequence Length (aa) |
12 |
| Functions |
protease binding, protein homodimerization activity, serine-type endopeptidase inhibitor activity |
| Preproprotein Length (aa) |
491 |
| Alt Name |
Alpha-2-plasmin inhibitor, Serpin F2 |
| Gene Name |
Serpinf2 |
| NCBI ID |
10090 |
| Cellular Localization |
cell surface, collagen-containing extracellular matrix, extracellular space, fibrinogen complex |
| Processes |
acute-phase response, blood vessel morphogenesis, collagen fibril organization, maintenance of blood vessel diameter homeostasis by renin-angiotensin, negative regulation of endopeptidase activity, negative regulation of fibrinolysis, negative regulation of plasminogen activation, positive regulation of cell differentiation, positive regulation of collagen biosynthetic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of JNK cascade, positive regulation of smooth muscle cell proliferation, positive regulation of stress fiber assembly, positive regulation of transcription by RNA polymerase II, positive regulation of transforming growth factor beta production |
| PubMed |
7523120
|
| Total Prosequence Length (aa) |
12 |
| Prosequence Location |
28:39 |
| Prosequence Sequence |
VDLPGQQPVSEQ |
| Preproprotein Sequence |
MALLRGLLVLSLSCLQGPCFTFSPVSAVDLPGQQPVSEQAQQKLPLPALFKLDNQDFGDHATLKRSPGHCKSVPTAEETRRLAQAMMAFTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGAQNQTLHSLHRVLHMNTGSCLPHLLSHFYQNLGPGTIRLAARIYLQKGFPIKDDFLEQSERLFGAKPVKLTGKQEEDLANINQWVKEATEGKIEDFLSELPDSTVLLLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFTVSVDMMHAVSYPLRWFLLEQPEIQVAHFPFKNNMSFVVVMPTYFEWNVSEVLANLTWDTLYHPSLQERPTKVWLPKLHLQQQLDLVATLSQLGLQELFQGPDLRGISEQNLVVSSVQHQSTMELSEAGVEAAAATSVAMNRMSLSSFTVNRPFLFFIMEDTIGVPLFVGSVRNPNPSALPQLQEQRDSPDNRLIGQNDKADFHGGKTFGPDLKLAPRMEEDYPQFSSPK |
