Details of PSQ01113
| ProSeqID |
PSQ01113 |
| Family |
FD00004 |
| Protein Name |
Azurocidin |
| UniProt ID |
P20160
|
| Taxonomy |
Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Primates-Haplorrhini-Catarrhini-Hominidae-Homo |
| Organisms |
Homo sapiens (Human) |
| Prosequence Length (aa) |
7 |
| Functions |
heparan sulfate proteoglycan binding, heparin binding, peptidase activity, serine-type endopeptidase activity, toxic substance binding |
| Preproprotein Length (aa) |
251 |
| Alt Name |
Cationic antimicrobial protein CAP37 , Heparin-binding protein |
| Gene Name |
AZU1 |
| NCBI ID |
9606 |
| Cellular Localization |
azurophil granule, azurophil granule lumen, azurophil granule membrane, extracellular exosome, extracellular region, extracellular space, extrinsic component of membrane, intracellular membrane-bounded organelle |
| Processes |
antimicrobial humoral response, calcium-mediated signaling using intracellular calcium source, cell chemotaxis, cellular extravasation, defense response to Gram-negative bacterium, defense response to virus, glial cell migration, induction of positive chemotaxis, inflammatory response, macrophage chemotaxis, microglial cell activation, monocyte activation, negative regulation of apoptotic process, neutrophil degranulation, neutrophil-mediated killing of bacterium, positive regulation of cell adhesion, positive regulation of fractalkine production, positive regulation of gene expression, positive regulation of interleukin-1 beta production, positive regulation of MHC class II biosynthetic process, positive regulation of peptidyl-threonine phosphorylation, positive regulation of phagocytosis, positive regulation of protein kinase activity, positive regulation of tumor necrosis factor production, protein kinase C signaling, protein kinase C-activating G protein-coupled receptor signaling pathway, proteolysis, regulation of vascular permeability |
| PubMed |
10534120,
1399008,
1897955,
1937776,
2026172,
2226832,
2332502,
2404977,
2406527,
2501794
|
| Total Prosequence Length (aa) |
7 |
| Prosequence Location |
20:26 |
| Prosequence Sequence |
GSSPLLD |
| Preproprotein Sequence |
MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA |
