Details of PSQ00819
| ProSeqID |
PSQ00819 |
| Family |
FD00118 |
| Protein Name |
Alpha-2-antiplasmin |
| UniProt ID |
P08697
|
| Taxonomy |
Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Primates-Haplorrhini-Catarrhini-Hominidae-Homo |
| Organisms |
Homo sapiens (Human) |
| Prosequence Length (aa) |
12 |
| Functions |
endopeptidase inhibitor activity, protease binding, protein homodimerization activity, serine-type endopeptidase inhibitor activity |
| Preproprotein Length (aa) |
491 |
| Alt Name |
Alpha-2-plasmin inhibitor, Serpin F2 |
| Gene Name |
SERPINF2 |
| NCBI ID |
9606 |
| Cellular Localization |
blood microparticle, cell surface, collagen-containing extracellular matrix, extracellular exosome, extracellular region, extracellular space, fibrinogen complex, platelet alpha granule lumen |
| Processes |
acute-phase response, blood vessel morphogenesis, collagen fibril organization, fibrinolysis, maintenance of blood vessel diameter homeostasis by renin-angiotensin, negative regulation of endopeptidase activity, negative regulation of fibrinolysis, negative regulation of plasminogen activation, platelet degranulation, positive regulation of cell differentiation, positive regulation of cell-cell adhesion mediated by cadherin, positive regulation of collagen biosynthetic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of JNK cascade, positive regulation of smooth muscle cell proliferation, positive regulation of stress fiber assembly, positive regulation of transcription by RNA polymerase II, positive regulation of transforming growth factor beta production, response to organic substance |
| PubMed |
14751930,
16223769,
21075,
2440681
|
| Total Prosequence Length (aa) |
12 |
| Prosequence Location |
28:39 |
| Prosequence Sequence |
MEPLGRQLTSGP |
| Preproprotein Sequence |
MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQTALKSPPGVCSRDPTPEQTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLKLVPPMEEDYPQFGSPK |
