Details of PSQ00806
| ProSeqID |
PSQ00806 |
| Family |
FD00012 |
| Protein Name |
Procathepsin L |
| UniProt ID |
P07711
|
| Taxonomy |
Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Primates-Haplorrhini-Catarrhini-Hominidae-Homo |
| Organisms |
Homo sapiens (Human) |
| Prosequence Length (aa) |
96 |
| Functions |
collagen binding, cysteine-type endopeptidase activity, cysteine-type peptidase activity, fibronectin binding, histone binding, proteoglycan binding, serpin family protein binding |
| Preproprotein Length (aa) |
333 |
| Alt Name |
Cathepsin L1 , Major excreted protein |
| Gene Name |
CTSL |
| NCBI ID |
9606 |
| Cellular Localization |
apical plasma membrane, chromaffin granule, collagen-containing extracellular matrix, endocytic vesicle lumen, endolysosome lumen, extracellular exosome, extracellular region, extracellular space, Golgi apparatus, intracellular membrane-bounded organelle, lysosomal lumen, lysosome, multivesicular body, nucleus, plasma membrane |
| Processes |
adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen, CD4-positive, alpha-beta T cell lineage commitment, cellular response to thyroid hormone stimulus, collagen catabolic process, elastin catabolic process, enkephalin processing, extracellular matrix disassembly, fusion of virus membrane with host endosome membrane, fusion of virus membrane with host plasma membrane, immune response, macrophage apoptotic process, protein autoprocessing, proteolysis, proteolysis involved in cellular protein catabolic process, receptor-mediated endocytosis of virus by host cell, regulation of keratinocyte differentiation, toll-like receptor signaling pathway, viral entry into host cell, zymogen activation |
| PubMed |
9468501
|
| Total Prosequence Length (aa) |
96 |
| Prosequence Location |
18:113 |
| Prosequence Sequence |
TLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYE |
| Preproprotein Sequence |
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV |
