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Details of PSQ00754

ProSeqID PSQ00754
Family FD00010
Protein Name Phospholipase A2
UniProt ID P04055
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Rattus
Organisms Rattus norvegicus (Rat)
Prosequence Length (aa) 7
Functions bile acid binding, calcium ion binding, calcium-dependent phospholipase A2 activity, phospholipase A2 activity, phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine), phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine), signaling receptor binding
Preproprotein Length (aa) 146
Alt Name Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B
Gene Name Pla2g1b
NCBI ID 10116
Cellular Localization cell surface, extracellular region, extracellular space, secretory granule
Processes antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, arachidonic acid secretion, cellular response to insulin stimulus, defense response to Gram-positive bacterium, fatty acid biosynthetic process, innate immune response in mucosa, lipid catabolic process, phosphatidylcholine metabolic process, phosphatidylglycerol metabolic process, phospholipid metabolic process, positive regulation of cell population proliferation, positive regulation of fibroblast proliferation, positive regulation of glomerular visceral epithelial cell apoptotic process, regulation of glucose import
PubMed 6501264
Total Prosequence Length (aa) 7
Prosequence Location 16:22
Prosequence Sequence AHSISTR
Preproprotein Sequence MKLLLLAALLTAGVTAHSISTRAVWQFRNMIKCTIPGSDPLREYNNYGCYCGLGGSGTPVDDLDRCCQTHDHCYNQAKKLESCKFLIDNPYTNTYSYKCSGNVITCSDKNNDCESFICNCDRQAAICFSKVPYNKEYKDLDTKKHC