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Details of PSQ00750

ProSeqID PSQ00750
Family FD00039
Protein Name Stromelysin-1
UniProt ID P03957
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Rattus
Organisms Rattus norvegicus (Rat)
Prosequence Length (aa) 80
Functions endopeptidase activity, metalloendopeptidase activity, metallopeptidase activity, peptidase activity, protein-containing complex binding, zinc ion binding
Preproprotein Length (aa) 480
Alt Name Matrix metalloproteinase-3, PTR1 protein, Transin-1
Gene Name Mmp3
NCBI ID 10116
Cellular Localization cell body, cytosol, dendrite, extracellular matrix, extracellular space, mitochondrion, nucleus, protein-containing complex
Processes cellular response to amino acid stimulus, cellular response to cell-matrix adhesion, cellular response to interleukin-1, cellular response to UV-A, collagen catabolic process, extracellular matrix organization, female pregnancy, negative regulation of hydrogen peroxide metabolic process, negative regulation of protein kinase B signaling, positive regulation of cell migration, positive regulation of oxidative stress-induced cell death, positive regulation of protein-containing complex assembly, protein catabolic process, proteolysis, regulation of cell migration, response to amino acid, response to cytokine, response to estradiol, response to hypoxia, response to interleukin-1, response to lipopolysaccharide, response to mechanical stimulus, response to tumor necrosis factor, wound healing
PubMed 2841336
Total Prosequence Length (aa) 80
Prosequence Location 18:97
Prosequence Sequence YPLHGSEEDAGMEVLQKYLENYYGLEKDVKQFTKKKDSSPVVKKIQEMQKFLGLKMTGKLDSNTMELMHKPRCGVPDVGG
Preproprotein Sequence MKGLPVLLWLCTAVCSSYPLHGSEEDAGMEVLQKYLENYYGLEKDVKQFTKKKDSSPVVKKIQEMQKFLGLKMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKNHISYRIVNYTLDLPRESVDSAIERALKVWEEVTPLTFSRISEGEADIMISFAVEEHGDFIPFDGPGMVLAHAYAPGPGTNGDAHFDDDERWTDDVTGTNLFLVAAHELGHSLGLFHSANAEALMYPVYKSSTDLARFHLSQDDVDGIQSLYGPPTESPDVLVVPTKSNSLDPETLPMCSSALSFDAVSTLRGEVLFFKDRHFWRKSLRTPEPGFYLISSFWPSLPSNMDAAYEVTNRDTVFILKGNQIWAIRGHEELAGYPKSIHTLGLPETVQKIDAAISLKDQKKTYFFVEDKFWRFDEKKQSMDPEFPRKIAENFPGIGTKVDAVFEAFGFLYFFSGSSQLEFDPNAGKVTHILKSNSWFNC