Details of PSQ02097
| ProSeqID |
PSQ02097 |
| Family |
FD00448 |
| Protein Name |
Heparanase |
| UniProt ID |
Q9Y251
|
| Taxonomy |
Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Primates-Haplorrhini-Catarrhini-Hominidae-Homo |
| Organisms |
Homo sapiens (Human) |
| Prosequence Length (aa) |
48 |
| Functions |
beta-glucuronidase activity, heparanase activity, syndecan binding |
| Preproprotein Length (aa) |
543 |
| Alt Name |
Endo-glucoronidase, Heparanase-1 |
| Gene Name |
HPSE |
| NCBI ID |
9606 |
| Cellular Localization |
extracellular matrix, extracellular region, heparanase complex, intracellular membrane-bounded organelle, lysosomal lumen, lysosomal membrane, lysosome, membrane raft, nucleoplasm, nucleus, specific granule lumen |
| Processes |
angiogenesis involved in wound healing, cell-matrix adhesion, glycosaminoglycan catabolic process, heparan sulfate proteoglycan catabolic process, neutrophil degranulation, positive regulation of blood coagulation, positive regulation of hair follicle development, positive regulation of osteoblast proliferation, positive regulation of protein kinase B signaling, positive regulation of vascular endothelial growth factor production, proteoglycan metabolic process, regulation of hair follicle development, vascular wound healing |
| PubMed |
10395326,
10446189,
12713442
|
| Total Prosequence Length (aa) |
48 |
| Prosequence Location |
110:157 |
| Prosequence Sequence |
STFEERSYWQSQVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQ |
| Preproprotein Sequence |
MLLRSKPALPPPLMLLLLGPLGPLSPGALPRPAQAQDVVDLDFFTQEPLHLVSPSFLSVTIDANLATDPRFLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPKKESTFEERSYWQSQVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLYTFANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADIFINGSQLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYLNGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAPLLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKLVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYLRLPYPFSNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYSFFVIRNAKVAACI |
