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Details of PSQ02093

ProSeqID PSQ02093
Family FD00502
Protein Name Caspase Dronc
UniProt ID Q9XYF4
Taxonomy Eukaryota-Metazoa-Ecdysozoa-Arthropoda-Hexapoda-Insecta-Pterygota-Neoptera-Holometabola-Diptera-Brachycera-Muscomorpha-Ephydroidea-Drosophilidae-Drosophila-Sophophora
Organisms Drosophila melanogaster (Fruit fly)
Prosequence Length (aa) 134
Functions CARD domain binding, cysteine-type endopeptidase activity, cysteine-type endopeptidase activity involved in apoptotic process, cysteine-type endopeptidase activity involved in apoptotic signaling pathway, cysteine-type endopeptidase activity involved in execution phase of apoptosis, endopeptidase activity, protein homodimerization activity
Preproprotein Length (aa) 450
Alt Name NEDD2-like caspase
Gene Name Dronc
NCBI ID 7227
Cellular Localization apoptosome, cytoplasm, nucleus, plasma membrane
Processes activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, central nervous system development, chaeta development, compound eye development, dendrite morphogenesis, determination of adult lifespan, ectopic germ cell programmed cell death, embryonic development via the syncytial blastoderm, execution phase of apoptosis, head involution, hemocyte development, melanization defense response, metamorphosis, negative regulation of cell population proliferation, neuron remodeling, nurse cell apoptotic process, positive regulation of apoptotic process, positive regulation of compound eye retinal cell programmed cell death, positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, positive regulation of necrotic cell death, programmed cell death, programmed cell death involved in cell development, protein autoprocessing, regulation of autophagy, regulation of cell death, salivary gland histolysis, sperm individualization, zymogen activation
PubMed 10200258
Total Prosequence Length (aa) 134
Prosequence Location 1:134
Prosequence Sequence MQPPELEIGMPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHRRLLLKITQRGPTAYNLLINALRNINCLDAAVLLESVDESDSRPPFISLNERRTSRKSADIV
Preproprotein Sequence MQPPELEIGMPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHRRLLLKITQRGPTAYNLLINALRNINCLDAAVLLESVDESDSRPPFISLNERRTSRKSADIVDTPSPEASEGPCVSKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILGTYKMQSRFNRGVLLMVNIMDYPDQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNLGFNKKLYFNPGFFNE