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Details of PSQ02016

ProSeqID PSQ02016
Family FD00324
Protein Name Metalloendopeptidase OMA1
UniProt ID Q9D8H7
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Mus-Mus
Organisms Mus musculus (Mouse)
Prosequence Length (aa) 60
Functions lipid binding, metal ion binding, metalloendopeptidase activity
Preproprotein Length (aa) 521
Alt Name Overlapping with the m-AAA protease 1 homolog
Gene Name Oma1
NCBI ID 10090
Cellular Localization integral component of membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion
Processes cristae formation, diet induced thermogenesis, energy homeostasis, glucose metabolic process, HRI-mediated signaling, integrated stress response signaling, lipid metabolic process, mitochondrial protein processing, mitochondrial respiratory chain complex assembly, mitochondrion organization, negative regulation of mitochondrial fusion, positive regulation of apoptotic process, positive regulation of cold-induced thermogenesis, protein autoprocessing, protein quality control for misfolded or incompletely synthesized proteins, regulation of cristae formation, zymogen activation
PubMed 24550258
Total Prosequence Length (aa) 60
Prosequence Location 80:139
Prosequence Sequence SSAQSKELGVLTYRCTVRGDSVLRQGARKVAGVPALAASCSPSCPAVIEARSFRTSARVQ
Preproprotein Sequence MSLLYGLQSTRINRFLSGVNNLANRRQWTPPASCPLAPKLRAVNAYWGLNTVSHCHSVTLLPRNFLFCRTLNHKKSRCLSSAQSKELGVLTYRCTVRGDSVLRQGARKVAGVPALAASCSPSCPAVIEARSFRTSARVQAAPVPLLLLILKPVQKLLAIIVGRGIRKWWQALPPNKKELFKDSVRKNKWRLLLGLSAFGLLFVVFYFTHLEVSPVTGRSKLLLVGKEHFRLLSDLEYEVWMEEFKNDLLPERDPRYLTVKEMVYHLTQCNRDVPGISETNWVVHVVDSPAVNAFVLPNGQVFIFTGLLNSVTDVHQLSFLLGHEIAHAVLGHAAEKASLVHLLDFLGMIFLTMIWAICPRDSLAVLGQWIQSKLQEYMFDRPYSRTLEAEADKVGLQLAAKACADVRASSVFWQQMEFSESLHGYPKLPEWLSTHPSHGNRAEYLDRLIPQALKLREVCNCPPLSGPDPRLLFRLTVKRFLEDSEKEDLNITVKKQKTDALPMQKQEQIPLTYVLEKRTAG