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Details of PSQ01834

ProSeqID PSQ01834
Family FD00197
Protein Name Ectonucleotide pyrophosphatase
UniProt ID Q64610
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Rattus
Organisms Rattus norvegicus (Rat)
Prosequence Length (aa) 8
Functions alkylglycerophosphoethanolamine phosphodiesterase activity, calcium ion binding, lysophospholipase activity, nucleic acid binding, nucleotide diphosphatase activity, phosphodiesterase I activity, polysaccharide binding, scavenger receptor activity, zinc ion binding
Preproprotein Length (aa) 887
Alt Name Autotaxin , Extracellular lysophospholipase D
Gene Name Enpp2
NCBI ID 10116
Cellular Localization cytoplasm, extracellular space, Golgi apparatus
Processes cell chemotaxis, cellular response to cadmium ion, cellular response to estradiol stimulus, estrous cycle, immune response, negative regulation of cell-matrix adhesion, phosphatidylcholine catabolic process, phospholipid catabolic process, phospholipid metabolic process, positive regulation of cell population proliferation, positive regulation of epithelial cell migration, positive regulation of focal adhesion assembly, positive regulation of lamellipodium morphogenesis, positive regulation of oligodendrocyte differentiation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of substrate adhesion-dependent cell spreading, regulation of angiogenesis, regulation of cell migration, response to polycyclic arene, sphingolipid catabolic process
PubMed 15985467, 16436050
Total Prosequence Length (aa) 8
Prosequence Location 28:35
Prosequence Sequence FTASRIKR
Preproprotein Sequence MARQGCLGSFQVISLFTFAISVNICLGFTASRIKRAEWDEGPPTVLSDSPWTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIKVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKSINNSKYDPKTIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPDEVSRPNYPGIMYLQSEFDLGCTCDDKVEPKNKLEELNKRLHTKGSTEAETGKFRGSKHENKKNLNGSVEPRKERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWAYFQRVLVKKYASERNGVNVISGPIFDYNYDGLRDTEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYESEI