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Details of PSQ01603

ProSeqID PSQ01603
Family FD00169
Protein Name Inhibin beta A chain
UniProt ID Q04998
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Mus-Mus
Organisms Mus musculus (Mouse)
Prosequence Length (aa) 288
Functions cytokine activity, growth factor activity, hormone activity, identical protein binding, inhibin binding, peptide hormone binding, protein-containing complex binding, signaling receptor binding, type II activin receptor binding
Preproprotein Length (aa) 424
Alt Name Activin beta-A chain
Gene Name Inhba
NCBI ID 10090
Cellular Localization activin A complex, extracellular region, extracellular space, inhibin A complex, perinuclear region of cytoplasm
Processes activin receptor signaling pathway, cell cycle arrest, cellular response to cholesterol, cellular response to follicle-stimulating hormone stimulus, endodermal cell differentiation, extrinsic apoptotic signaling pathway, eyelid development in camera-type eye, G1/S transition of mitotic cell cycle, GABAergic neuron differentiation, hair follicle development, hematopoietic progenitor cell differentiation, hemoglobin biosynthetic process, male gonad development, mesoderm formation, mesodermal cell differentiation, negative regulation of cell cycle, negative regulation of cell growth, negative regulation of cell population proliferation, negative regulation of hair follicle development, odontogenesis, ovarian follicle development, positive regulation of cellular protein metabolic process, positive regulation of erythrocyte differentiation, positive regulation of extrinsic apoptotic signaling pathway in absence of ligand, positive regulation of gene expression, positive regulation of ovulation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, progesterone secretion, regulation of follicle-stimulating hormone secretion, regulation of transcription by RNA polymerase II, response to drug, roof of mouth development, SMAD protein signal transduction, striatal medium spiny neuron differentiation
PubMed 2133547
Total Prosequence Length (aa) 288
Prosequence Location 21:308
Prosequence Sequence SPTPGSEGHGSAPDCPSCALATLPKDGPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGDEAEEMGLKGERSELLLSEKVVDARKSTWHIFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEVDGDGKKKDGSDGGLEEEKEQSHRPFLMLQARQSEDHPHRRRRR
Preproprotein Sequence MPLLWLRGFLLASCWIIVRSSPTPGSEGHGSAPDCPSCALATLPKDGPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGDEAEEMGLKGERSELLLSEKVVDARKSTWHIFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEVDGDGKKKDGSDGGLEEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS