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Details of PSQ01588

ProSeqID PSQ01588
Family FD00313
Protein Name Decorin
UniProt ID Q01129
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Rattus
Organisms Rattus norvegicus (Rat)
Prosequence Length (aa) 14
Functions collagen binding, extracellular matrix binding, extracellular matrix structural constituent conferring compression resistance, glycosaminoglycan binding, protein N-terminus binding
Preproprotein Length (aa) 360
Alt Name Bone proteoglycan II, Dermatan sulfate proteoglycan-II, PG-S2, PG40
Gene Name Dcn
NCBI ID 10116
Cellular Localization collagen type VI trimer, extracellular matrix, extracellular space
Processes aging, kidney development, negative regulation of angiogenesis, negative regulation of endothelial cell migration, negative regulation of vascular endothelial growth factor signaling pathway, peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, placenta development, positive regulation of autophagy, positive regulation of macroautophagy, positive regulation of mitochondrial depolarization, positive regulation of mitochondrial fission, positive regulation of phosphatidylinositol 3-kinase signaling, positive regulation of transcription by RNA polymerase II, response to lipopolysaccharide, response to mechanical stimulus, skeletal muscle tissue development, wound healing
PubMed 26479776, 2764879
Total Prosequence Length (aa) 14
Prosequence Location 17:30
Prosequence Sequence GPFEQRGLFDFMLE
Preproprotein Sequence MKATLVLFLLAQVSWAGPFEQRGLFDFMLEDEASGIIPYDPDNPLISMCPYRCQCHLRVVQCSDLGLDKVPWEFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTLILVNNKISKISPEAFKPLVKLERLYLSKNHLKELPEKLPKTLQELRLHDNEITKLKKSVFNGLNRMIVIELGGNPLKNSGIENGALQGMKGLGYIRISDTNITAIPQGLPTSISELHLDGNKIAKVDAASLKGMSNLSKLGLSFNSITVVENGSLANVPHLRELHLDNNKLLRVPAGLAQHKYVQVVYLHNNNISEVGQHDFCLPSYQTRKTSYTAVSLYSNPVRYWQIHPHTFRCVFGRSTIQLGNYKn