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Details of PSQ01574

ProSeqID PSQ01574
Family FD00075
Protein Name Zona pellucida sperm-binding protein 3
UniProt ID P97708
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Rattus
Organisms Rattus norvegicus (Rat)
Prosequence Length (aa) 73
Functions acrosin binding, carbohydrate binding, receptor ligand activity, structural constituent of egg coat
Preproprotein Length (aa) 424
Alt Name Zona pellucida glycoprotein 3, Zona pellucida protein C
Gene Name Zp3
NCBI ID 10116
Cellular Localization collagen-containing extracellular matrix, egg coat, extracellular matrix, extracellular space, integral component of membrane, plasma membrane
Processes binding of sperm to zona pellucida, blastocyst formation, egg coat formation, humoral immune response mediated by circulating immunoglobulin, negative regulation of binding of sperm to zona pellucida, negative regulation of transcription, DNA-templated, oocyte development, phosphatidylinositol-mediated signaling, positive regulation of acrosomal vesicle exocytosis, positive regulation of acrosome reaction, positive regulation of antral ovarian follicle growth, positive regulation of humoral immune response, positive regulation of inflammatory response, positive regulation of interferon-gamma production, positive regulation of interleukin-4 production, positive regulation of leukocyte migration, positive regulation of ovarian follicle development, positive regulation of T cell proliferation, positive regulation of transcription, DNA-templated, positive regulation of type IV hypersensitivity, regulation of signaling receptor activity
PubMed 16342937
Total Prosequence Length (aa) 73
Prosequence Location 352:424
Prosequence Sequence RRHVTDEADVTVGPLIFLGKANDQAVEGWTSSAQTSVALGLGLATVAFLTLAAIVLGVTRKCHTSSYLVSLPQ
Preproprotein Sequence MGPSCLLFLCLLLCGGPELCYPQTQWLLPGGTPTPAGSSSPVEVECKEAELVVTVRRDLFGTGKLVQPGDLTLGSEGCQPLVAVDTDVVRLNAQLHECSSGVQVTEDALVYNTFLLHDPRPVNGLSILRTNRVEVPIECRYPRQGNVSSHPIQPTWVPFSATVSSEEKLAFSLRLMEEDWNTEKSSPTFHLGEVAHLQAEVQTGSHLPLQLFVDHCVATPSPLPGQNSSPHHFIVDSHGCLVDGLSESFSAFQVPRPRPETLQFTVDVFHFANSSRNTVYITCHLKVAPANQIPDKLNKACSFNKTSQSWLPVEGDADICDCCSNGNCSNSSSSEFETHEPAQWSTLVSRNRRHVTDEADVTVGPLIFLGKANDQAVEGWTSSAQTSVALGLGLATVAFLTLAAIVLGVTRKCHTSSYLVSLPQ