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Details of PSQ01128

ProSeqID PSQ01128
Family FD00254
Protein Name Decorin
UniProt ID P21793
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Laurasiatheria-Artiodactyla-Ruminantia-Pecora-Bovidae-Bovinae-Bos
Organisms Bos taurus (Bovine)
Prosequence Length (aa) 14
Functions collagen binding, collagen fibril binding, extracellular matrix binding, extracellular matrix structural constituent conferring compression resistance, glycosaminoglycan binding, protein homodimerization activity
Preproprotein Length (aa) 360
Alt Name Bone proteoglycan II, PG-S2
Gene Name DCN
NCBI ID 9913
Cellular Localization collagen-containing extracellular matrix, extracellular space
Processes negative regulation of angiogenesis, negative regulation of collagen fibril organization, negative regulation of endothelial cell migration, negative regulation of vascular endothelial growth factor signaling pathway, peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, positive regulation of macroautophagy, positive regulation of mitochondrial depolarization, positive regulation of mitochondrial fission, positive regulation of phosphatidylinositol 3-kinase signaling, positive regulation of transcription by RNA polymerase II
PubMed 2914936
Total Prosequence Length (aa) 14
Prosequence Location 17:30
Prosequence Sequence GPFQQKGLFDFMLE
Preproprotein Sequence MKATIIFLLVAQVSWAGPFQQKGLFDFMLEDEASGIGPEEHFPEVPEIEPMGPVCPFRCQCHLRVVQCSDLGLEKVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVRKSVFNGLNQMIVVELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTELHLDGNKITKVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKLVKVPGGLADHKYIQVVYLHNNNISAIGSNDFCPPGYNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRAAVQLGNYK