ProSeqID | PSQ01085 |
Family | FD00322 |
Protein Name | Protein-lysine 6-oxidase |
UniProt ID | P16636 |
Taxonomy | Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Rattus |
Organisms | Rattus norvegicus (Rat) |
Prosequence Length (aa) | 141 |
Functions | collagen binding, copper ion binding, protein-lysine 6-oxidase activity |
Preproprotein Length (aa) | 418 |
Alt Name | Lysyl oxidase |
Gene Name | Lox |
NCBI ID | 10116 |
Cellular Localization | collagen trimer, extracellular matrix, extracellular region, extracellular space, nucleus |
Processes | aorta development, ascending aorta development, blood vessel development, blood vessel morphogenesis, bone mineralization, cell chemotaxis, cellular response to chemokine, cellular response to organic substance, collagen fibril organization, connective tissue development, descending aorta development, DNA biosynthetic process, elastic fiber assembly, heart development, lung development, muscle cell cellular homeostasis, muscle fiber development, osteoblast differentiation, peptidyl-lysine oxidation, platelet-derived growth factor receptor-beta signaling pathway, protein kinase B signaling, protein oxidation, regulation of apoptotic process, regulation of bone development, regulation of gene expression, regulation of megakaryocyte differentiation, regulation of platelet-derived growth factor receptor-beta signaling pathway, regulation of protein phosphorylation, regulation of receptor binding, regulation of striated muscle tissue development, regulation of transforming growth factor beta receptor signaling pathway, response to drug, response to hormone, response to steroid hormone, wound healing |
PubMed | 8636146 |
Total Prosequence Length (aa) | 141 |
Prosequence Location | 22:162 |
Prosequence Sequence | APQAPREPPAAPGAWRQTIQWENNGQVFSLLSLGAQYQPQRRRDSSATAPRADGNAAAQPRTPILLLRDNRTASARARTPSPSGVAAGRPRPAARHWFQVGFSPSGAGDGASRRAANRTASPQPPQLSNLRPPSHVDRMVG |
Preproprotein Sequence | MRFAWTVLFLGQLQFCPLLRCAPQAPREPPAAPGAWRQTIQWENNGQVFSLLSLGAQYQPQRRRDSSATAPRADGNAAAQPRTPILLLRDNRTASARARTPSPSGVAAGRPRPAARHWFQVGFSPSGAGDGASRRAANRTASPQPPQLSNLRPPSHVDRMVGDDPYNPYKYSDDNPYYNYYDTYERPRSGSRHRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYAADIDCQWIDITDVQPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY |