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Details of PSQ01085

ProSeqID PSQ01085
Family FD00322
Protein Name Protein-lysine 6-oxidase
UniProt ID P16636
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Rattus
Organisms Rattus norvegicus (Rat)
Prosequence Length (aa) 141
Functions collagen binding, copper ion binding, protein-lysine 6-oxidase activity
Preproprotein Length (aa) 418
Alt Name Lysyl oxidase
Gene Name Lox
NCBI ID 10116
Cellular Localization collagen trimer, extracellular matrix, extracellular region, extracellular space, nucleus
Processes aorta development, ascending aorta development, blood vessel development, blood vessel morphogenesis, bone mineralization, cell chemotaxis, cellular response to chemokine, cellular response to organic substance, collagen fibril organization, connective tissue development, descending aorta development, DNA biosynthetic process, elastic fiber assembly, heart development, lung development, muscle cell cellular homeostasis, muscle fiber development, osteoblast differentiation, peptidyl-lysine oxidation, platelet-derived growth factor receptor-beta signaling pathway, protein kinase B signaling, protein oxidation, regulation of apoptotic process, regulation of bone development, regulation of gene expression, regulation of megakaryocyte differentiation, regulation of platelet-derived growth factor receptor-beta signaling pathway, regulation of protein phosphorylation, regulation of receptor binding, regulation of striated muscle tissue development, regulation of transforming growth factor beta receptor signaling pathway, response to drug, response to hormone, response to steroid hormone, wound healing
PubMed 8636146
Total Prosequence Length (aa) 141
Prosequence Location 22:162
Prosequence Sequence APQAPREPPAAPGAWRQTIQWENNGQVFSLLSLGAQYQPQRRRDSSATAPRADGNAAAQPRTPILLLRDNRTASARARTPSPSGVAAGRPRPAARHWFQVGFSPSGAGDGASRRAANRTASPQPPQLSNLRPPSHVDRMVG
Preproprotein Sequence MRFAWTVLFLGQLQFCPLLRCAPQAPREPPAAPGAWRQTIQWENNGQVFSLLSLGAQYQPQRRRDSSATAPRADGNAAAQPRTPILLLRDNRTASARARTPSPSGVAAGRPRPAARHWFQVGFSPSGAGDGASRRAANRTASPQPPQLSNLRPPSHVDRMVGDDPYNPYKYSDDNPYYNYYDTYERPRSGSRHRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMSMYNLRCAAEENCLASSAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYAADIDCQWIDITDVQPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY