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Details of PSQ01054

ProSeqID PSQ01054
Family FD00547
Protein Name CD59 glycoprotein
UniProt ID P13987
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Primates-Haplorrhini-Catarrhini-Hominidae-Homo
Organisms Homo sapiens (Human)
Prosequence Length (aa) 26
Functions complement binding
Preproprotein Length (aa) 128
Alt Name 1F5 antigen, 20 kDa homologous restriction factor, MAC-inhibitory protein, MEM43 antigen, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
Gene Name CD59
NCBI ID 9606
Cellular Localization anchored component of external side of plasma membrane, cell surface, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, ER to Golgi transport vesicle membrane, extracellular exosome, extracellular space, focal adhesion, Golgi membrane, membrane, plasma membrane, specific granule membrane, tertiary granule membrane, transport vesicle, vesicle
Processes blood coagulation, cell surface receptor signaling pathway, COPII vesicle coating, endoplasmic reticulum to Golgi vesicle-mediated transport, negative regulation of activation of membrane attack complex, neutrophil degranulation, regulation of complement activation, regulation of complement-dependent cytotoxicity
PubMed 9054419
Total Prosequence Length (aa) 26
Prosequence Location 103:128
Prosequence Sequence GGTSLSEKTVLLLVTPFLAAAWSLHP
Preproprotein Sequence MGIQGGSVLFGLLLVLAVFCHSGHSLQCYNCPNPTADCKTAVNCSSDFDACLITKAGLQVYNKCWKFEHCNFNDVTTRLRENELTYYCCKKDLCNFNEQLENGGTSLSEKTVLLLVTPFLAAAWSLHP