Details of PSQ01025
| ProSeqID |
PSQ01025 |
| Family |
FD00593 |
| Protein Name |
Lysosomal alpha-glucosidase |
| UniProt ID |
P10253
|
| Taxonomy |
Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Primates-Haplorrhini-Catarrhini-Hominidae-Homo |
| Organisms |
Homo sapiens (Human) |
| Prosequence Length (aa) |
42 |
| Functions |
alpha-1,4-glucosidase activity, carbohydrate binding, hydrolase activity, hydrolyzing O-glycosyl compounds, maltose alpha-glucosidase activity |
| Preproprotein Length (aa) |
959 |
| Alt Name |
Acid maltase, Aglucosidase alfa |
| Gene Name |
GAA |
| NCBI ID |
9606 |
| Cellular Localization |
azurophil granule membrane, extracellular exosome, ficolin-1-rich granule membrane, intracellular membrane-bounded organelle, lysosomal lumen, lysosomal membrane, lysosome, membrane, plasma membrane, tertiary granule membrane |
| Processes |
cardiac muscle contraction, diaphragm contraction, glucose metabolic process, glycogen catabolic process, heart morphogenesis, locomotory behavior, lysosome organization, maltose metabolic process, muscle cell cellular homeostasis, neuromuscular process controlling balance, neuromuscular process controlling posture, neutrophil degranulation, regulation of the force of heart contraction, sucrose metabolic process, tissue development, vacuolar sequestering |
| PubMed |
3049072
|
| Total Prosequence Length (aa) |
42 |
| Prosequence Location |
28:69 |
| Prosequence Sequence |
GHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRDAQ |
| Preproprotein Sequence |
MGVRHPPCSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLSNGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC |
