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Details of PSQ00838

ProSeqID PSQ00838
Family FD00096
Protein Name Somatoliberin
UniProt ID P09916
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Rattus
Organisms Rattus norvegicus (Rat)
Prosequence Length (aa) 11
Functions growth hormone-releasing hormone activity, growth hormone-releasing hormone receptor binding, neuropeptide hormone activity, peptide hormone receptor binding
Preproprotein Length (aa) 104
Alt Name Growth hormone-releasing factor, Growth hormone-releasing hormone
Gene Name Ghrh
NCBI ID 10116
Cellular Localization axon terminus, extracellular space, neuron projection, perikaryon, terminal bouton
Processes adenohypophysis development, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, cellular response to interleukin-6, circadian sleep/wake cycle, non-REM sleep, growth hormone secretion, negative regulation of cardiac muscle cell apoptotic process, positive regulation of cAMP-mediated signaling, positive regulation of cell population proliferation, positive regulation of circadian sleep/wake cycle, non-REM sleep, positive regulation of cytosolic calcium ion concentration, positive regulation of growth hormone secretion, positive regulation of hormone secretion, positive regulation of multicellular organism growth, positive regulation of transcription, DNA-templated, response to dexamethasone, response to food, response to hypoxia, response to leptin
PubMed 6406907
Total Prosequence Length (aa) 11
Prosequence Location 20:30
Prosequence Sequence LPPSPPFRVRR
Preproprotein Sequence MPLWVFFVLLTLTSGSHCSLPPSPPFRVRRHADAIFTSSYRRILGQLYARKLLHEIMNRQQGERNQEQRSRFNRHLDRVWAEDKQMALESILQGFPRMKLSAEA