Details of PSQ00815
| ProSeqID |
PSQ00815 |
| Family |
FD00403 |
| Protein Name |
Leishmanolysin |
| UniProt ID |
P08148
|
| Taxonomy |
Eukaryota-Discoba-Euglenozoa-Kinetoplastea-Metakinetoplastina-Trypanosomatida-Trypanosomatidae-Leishmaniinae-Leishmania |
| Organisms |
Leishmania major |
| Prosequence Length (aa) |
61, 25 |
| Functions |
metal ion binding, metalloendopeptidase activity, metallopeptidase activity |
| Preproprotein Length (aa) |
602 |
| Alt Name |
Cell surface protease, Major surface glycoprotein, Major surface protease, Promastigote surface endopeptidase, Protein gp63 |
| Gene Name |
gp63 |
| NCBI ID |
5664 |
| Cellular Localization |
anchored component of membrane, plasma membrane |
| Processes |
catabolism by symbiont of host protein, cell adhesion, induction by symbiont of host cytokine production, modulation by symbiont of host inflammatory response |
| PubMed |
33466252145267
|
| Total Prosequence Length (aa) |
86 |
| Prosequence Location |
40:100, 578:602 |
| Prosequence Sequence |
HAGALQHRCVHDAMQARVRQSVADHHKAPGAVSAVGLPYVTLDAAHTAAAADPRPGSARSV, TAAGRRGPRAAATALLVAALLAVAL |
| Preproprotein Sequence |
MSVDSSSTHRRRCVAARLVRLAAAGAAVTVAVGTAAAWAHAGALQHRCVHDAMQARVRQSVADHHKAPGAVSAVGLPYVTLDAAHTAAAADPRPGSARSVVRDVNWGALRIAVSTEDLTDPAYHCARVGQHVKDHAGAIVTCTAEDILTNEKRDILVKHLIPQAVQLHTERLKVQQVQGKWKVTDMVGDICGDFKVPQAHITEGFSNTDFVMYVASVPSEEGVLAWATTCQTFSDGHPAVGVINIPAANIASRYDQLVTRVVTHEMAHALGFSGPFFEDARIVANVPNVRGKNFDVPVINSSTAVAKAREQYGCDTLEYLEVEDQGGAGSAGSHIKMRNAQDELMAPAAAAGYYTALTMAIFQDLGFYQADFSKAEVMPWGQNAGCAFLTNKCMEQSVTQWPAMFCNESEDAIRCPTSRLSLGACGVTRHPGLPPYWQYFTDPSLAGVSAFMDYCPVVVPYSDGSCTQRASEAHASLLPFNVFSDAARCIDGAFRPKATDGIVKSYAGLCANVQCDTATRTYSVQVHGSNDYTNCTPGLRVELSTVSNAFEGGGYITCPPYVEVCQGNVQAAKDGGNTAAGRRGPRAAATALLVAALLAVAL |
