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Details of PSQ00807

ProSeqID PSQ00807
Family FD00440
Protein Name Protein decapentaplegic
UniProt ID P07713
Taxonomy Eukaryota-Metazoa-Ecdysozoa-Arthropoda-Hexapoda-Insecta-Pterygota-Neoptera-Holometabola-Diptera-Brachycera-Muscomorpha-Ephydroidea-Drosophilidae-Drosophila-Sophophora
Organisms Drosophila melanogaster (Fruit fly)
Prosequence Length (aa) 433
Functions BMP receptor binding, collagen binding, cytokine activity, growth factor activity, heparin binding, morphogen activity, protein heterodimerization activity, protein homodimerization activity, receptor ligand activity
Preproprotein Length (aa) 588
Alt Name None
Gene Name dpp
NCBI ID 7227
Cellular Localization cell leading edge, dense core granule lumen, extracellular space
Processes amnioserosa formation, anterior Malpighian tubule development, BMP signaling pathway, cardioblast differentiation, cell chemotaxis involved in Malpighian tubule morphogenesis, chorion-containing eggshell formation, compound eye morphogenesis, dorsal appendage formation, dorsal closure, dorsal/ventral axis specification, dorsal/ventral pattern formation, ectodermal cell fate specification, embryonic hindgut morphogenesis, epithelial cell migration, open tracheal system, eye-antennal disc development, eye-antennal disc morphogenesis, female germ-line stem cell population maintenance, fusion cell fate specification, genital disc anterior/posterior pattern formation, genital disc development, genital disc sexually dimorphic development, germ cell development, germ cell migration, germ-line stem cell division, germ-line stem cell population maintenance, head morphogenesis, heart development, hemocyte development, hindgut morphogenesis, imaginal disc development, imaginal disc-derived wing morphogenesis, imaginal disc-derived wing vein morphogenesis, imaginal disc-derived wing vein specification, labial disc development, larval lymph gland hemocyte differentiation, lymph gland development, male germ-line stem cell population maintenance, Malpighian tubule morphogenesis, maternal specification of dorsal/ventral axis, oocyte, soma encoded, mesoderm development, negative regulation of gene expression, negative regulation of salivary gland boundary specification, ovarian follicle cell development, pericardial nephrocyte differentiation, positive regulation of gene expression, positive regulation of imaginal disc growth, positive regulation of muscle organ development, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of SMAD protein signal transduction, progression of morphogenetic furrow involved in compound eye morphogenesis, R8 cell fate specification, regulation of cell differentiation, regulation of cell shape, regulation of imaginal disc growth, regulation of stem cell differentiation, regulation of tube diameter, open tracheal system, SMAD protein signal transduction, spectrosome organization, wing and notum subfield formation, wing disc pattern formation, zygotic specification of dorsal/ventral axis
PubMed 1692958
Total Prosequence Length (aa) 433
Prosequence Location 24:456
Prosequence Sequence EDISQRFIAAIAPVAAHIPLASASGSGSGRSGSRSVGASTSTALAKAFNPFSEPASFSDSDKSHRSKTNKKPSKSDANRQFNEVHKPRTDQLENSKNKSKQLVNKPNHNKMAVKEQRSHHKKSHHHRSHQPKQASASTESHQSSSIESIFVEEPTLVLDREVASINVPANAKAIIAEQGPSTYSKEALIKDKLKPDPSTLVEIEKSLLSLFNMKRPPKIDRSKIIIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIR
Preproprotein Sequence MRAWLLLLAVLATFQTIVRVASTEDISQRFIAAIAPVAAHIPLASASGSGSGRSGSRSVGASTSTALAKAFNPFSEPASFSDSDKSHRSKTNKKPSKSDANRQFNEVHKPRTDQLENSKNKSKQLVNKPNHNKMAVKEQRSHHKKSHHHRSHQPKQASASTESHQSSSIESIFVEEPTLVLDREVASINVPANAKAIIAEQGPSTYSKEALIKDKLKPDPSTLVEIEKSLLSLFNMKRPPKIDRSKIIIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKPAPHHHVRLRRSADEAHERWQHKQPLLFTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRPTRRKNHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGCR