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Details of PSQ00800

ProSeqID PSQ00800
Family FD00382
Protein Name Decorin
UniProt ID P07585
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Primates-Haplorrhini-Catarrhini-Hominidae-Homo
Organisms Homo sapiens (Human)
Prosequence Length (aa) 14
Functions collagen binding, extracellular matrix binding, extracellular matrix structural constituent conferring compression resistance, glycosaminoglycan binding, protein N-terminus binding, RNA binding
Preproprotein Length (aa) 360
Alt Name Bone proteoglycan II, PG-S2, PG40
Gene Name DCN
NCBI ID 9606
Cellular Localization collagen type VI trimer, collagen-containing extracellular matrix, extracellular region, extracellular space, Golgi lumen, lysosomal lumen
Processes aging, animal organ morphogenesis, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, dermatan sulfate biosynthetic process, extracellular matrix organization, kidney development, negative regulation of angiogenesis, negative regulation of endothelial cell migration, negative regulation of vascular endothelial growth factor signaling pathway, peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, placenta development, positive regulation of autophagy, positive regulation of macroautophagy, positive regulation of mitochondrial depolarization, positive regulation of mitochondrial fission, positive regulation of phosphatidylinositol 3-kinase signaling, positive regulation of transcription by RNA polymerase II, response to lipopolysaccharide, response to mechanical stimulus, skeletal muscle tissue development, wound healing
PubMed 2590169, 3597437
Total Prosequence Length (aa) 14
Prosequence Location 17:30
Prosequence Sequence GPFQQRGLFDFMLE
Preproprotein Sequence MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK