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Details of PSQ00779

ProSeqID PSQ00779
Family FD00099
Protein Name Renin-1
UniProt ID P06281
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Mus-Mus
Organisms Mus musculus (Mouse)
Prosequence Length (aa) 50
Functions aspartic-type endopeptidase activity, endopeptidase activity, insulin-like growth factor receptor binding, peptidase activity, signaling receptor binding
Preproprotein Length (aa) 402
Alt Name Angiotensinogenase, Kidney renin
Gene Name Ren1
NCBI ID 10090
Cellular Localization apical part of cell, cytoplasm, extracellular space, membrane
Processes amyloid-beta metabolic process, angiotensin maturation, cell maturation, cellular response to drug, drinking behavior, hormone-mediated signaling pathway, kidney development, male gonad development, mesonephros development, proteolysis, regulation of blood pressure, regulation of blood volume by renin-angiotensin, regulation of MAPK cascade, renin-angiotensin regulation of aldosterone production, response to cAMP, response to cGMP, response to drug, response to immobilization stress, response to lipopolysaccharide, response to organic substance
PubMed 9030738
Total Prosequence Length (aa) 50
Prosequence Location 22:71
Prosequence Sequence LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLT
Preproprotein Sequence MDRRRMPLWALLLLWSPCTFSLPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR