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Details of PSQ00763

ProSeqID PSQ00763
Family FD00230
Protein Name Serglycin
UniProt ID P04917
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Glires-Rodentia-Myomorpha-Muroidea-Muridae-Murinae-Rattus
Organisms Rattus norvegicus (Rat)
Prosequence Length (aa) 49
Functions collagen binding
Preproprotein Length (aa) 180
Alt Name Chondroitin sulfate proteoglycan core protein, Cytolytic granule proteoglycan core protein, PG19 core protein, Proteoglycan 10K core protein, Secretory granule proteoglycan core protein
Gene Name Srgn
NCBI ID 10116
Cellular Localization extracellular space, glutamatergic synapse, Golgi apparatus, mast cell granule, postsynaptic specialization, intracellular component, Schaffer collateral - CA1 synapse, secretory granule, zymogen granule
Processes apoptotic process, biomineral tissue development, granzyme-mediated programmed cell death signaling pathway, maintenance of granzyme B location in T cell secretory granule, maintenance of protease location in mast cell secretory granule, mast cell secretory granule organization, modulation of chemical synaptic transmission, negative regulation of bone mineralization, negative regulation of cytokine production, protein processing, regulation of postsynapse organization, secretory granule organization, T cell secretory granule organization
PubMed 3919394
Total Prosequence Length (aa) 49
Prosequence Location 27:75
Prosequence Sequence YPARRARYQWVRCKPDGIFANCIEEKGPRFDLIAEESNVGPPMTDPVLM
Preproprotein Sequence MRQVPVGTRLVLALAFVLVWGSSVQGYPARRARYQWVRCKPDGIFANCIEEKGPRFDLIAEESNVGPPMTDPVLMRGFPNDFFPISDDYSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSLADMEWEYQPTDENNIVYFNYGPFDRMLTEQNQEQPGDFII