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Details of PSQ00752

ProSeqID PSQ00752
Family FD00169
Protein Name Inhibin beta A chain
UniProt ID P03970
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Laurasiatheria-Artiodactyla-Suina-Suidae-Sus
Organisms Sus scrofa (Pig)
Prosequence Length (aa) 288
Functions cytokine activity, growth factor activity, hormone activity, identical protein binding, peptide hormone binding, type II activin receptor binding
Preproprotein Length (aa) 424
Alt Name Activin beta-A chain
Gene Name INHBA
NCBI ID 9823
Cellular Localization activin A complex, extracellular region, extracellular space, inhibin A complex, perinuclear region of cytoplasm
Processes activin receptor signaling pathway, cell cycle arrest, endodermal cell differentiation, extrinsic apoptotic signaling pathway, eyelid development in camera-type eye, G1/S transition of mitotic cell cycle, GABAergic neuron differentiation, hair follicle development, hematopoietic progenitor cell differentiation, hemoglobin biosynthetic process, male gonad development, mesodermal cell differentiation, negative regulation of cell cycle, negative regulation of cell growth, negative regulation of cell population proliferation, negative regulation of hair follicle development, odontogenesis, ovarian follicle development, positive regulation of erythrocyte differentiation, positive regulation of extrinsic apoptotic signaling pathway in absence of ligand, positive regulation of ovulation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, progesterone secretion, regulation of follicle-stimulating hormone secretion, regulation of transcription by RNA polymerase II, response to drug, roof of mouth development, SMAD protein signal transduction, striatal medium spiny neuron differentiation
PubMed 1644823
Total Prosequence Length (aa) 288
Prosequence Location 21:308
Prosequence Sequence SPTPGSGGHSAAPDCPSCALATLPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVELEDDIGRRAEMNELMEQTSEIITFAEAGTARKTLRFEISKEGSDLSVVERAEIWLFLKVPKANRTRTKVSIRLFQQQRRPQGSADAGEEAEDVGFPEEKSEVLISEKVVDARKSTWHIFPVSSSIQRLLDQGKSALDIRTACEQCHETGASLVLLGKKKKKEEEAEGRKRDGEGAGVDEEKEQSHRPFLMLQARQSEEHPHRRRRR
Preproprotein Sequence MPLLWLRGFLLASCWIIVRSSPTPGSGGHSAAPDCPSCALATLPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVELEDDIGRRAEMNELMEQTSEIITFAEAGTARKTLRFEISKEGSDLSVVERAEIWLFLKVPKANRTRTKVSIRLFQQQRRPQGSADAGEEAEDVGFPEEKSEVLISEKVVDARKSTWHIFPVSSSIQRLLDQGKSALDIRTACEQCHETGASLVLLGKKKKKEEEAEGRKRDGEGAGVDEEKEQSHRPFLMLQARQSEEHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS