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Details of PSQ00732

ProSeqID PSQ00732
Family FD00042
Protein Name Osteocalcin
UniProt ID P02818
Taxonomy Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Primates-Haplorrhini-Catarrhini-Hominidae-Homo
Organisms Homo sapiens (Human)
Prosequence Length (aa) 28
Functions calcium ion binding, hydroxyapatite binding, structural constituent of bone, structural molecule activity
Preproprotein Length (aa) 100
Alt Name Bone Gla protein, Gamma-carboxyglutamic acid-containing protein
Gene Name BGLAP
NCBI ID 9606
Cellular Localization cytoplasm, dendrite, endoplasmic reticulum lumen, extracellular region, extracellular space, Golgi lumen, perikaryon, rough endoplasmic reticulum, vesicle
Processes bone development, bone mineralization, cell adhesion, cell aging, cellular response to growth factor stimulus, cellular response to vitamin D, endoplasmic reticulum to Golgi vesicle-mediated transport, odontogenesis, osteoblast development, osteoblast differentiation, regulation of bone mineralization, regulation of bone resorption, regulation of cellular response to insulin stimulus, regulation of osteoclast differentiation, response to activity, response to drug, response to estrogen, response to ethanol, response to glucocorticoid, response to gravity, response to hydroxyisoflavone, response to mechanical stimulus, response to testosterone, response to vitamin D, response to vitamin K, response to zinc ion, skeletal system development
PubMed 6967872
Total Prosequence Length (aa) 28
Prosequence Location 24:51
Prosequence Sequence KPSGAESSKGAAFVSKQEGSEVVKRPRR
Preproprotein Sequence MRALTLLALLALAALCIAGQAGAKPSGAESSKGAAFVSKQEGSEVVKRPRRYLYQWLGAPVPYPDPLEPRREVCELNPDCDELADHIGFQEAYRRFYGPV