Details of PSQ00697
| ProSeqID |
PSQ00697 |
| Family |
FD00099 |
| Protein Name |
Renin |
| UniProt ID |
P00797
|
| Taxonomy |
Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Primates-Haplorrhini-Catarrhini-Hominidae-Homo |
| Organisms |
Homo sapiens (Human) |
| Prosequence Length (aa) |
43 |
| Functions |
aspartic-type endopeptidase activity, insulin-like growth factor receptor binding, peptidase activity, signaling receptor binding |
| Preproprotein Length (aa) |
406 |
| Alt Name |
Angiotensinogenase |
| Gene Name |
REN |
| NCBI ID |
9606 |
| Cellular Localization |
apical part of cell, cytoplasm, extracellular region, extracellular space, plasma membrane |
| Processes |
amyloid-beta metabolic process, angiotensin maturation, cell maturation, cellular response to drug, drinking behavior, hormone-mediated signaling pathway, kidney development, male gonad development, mesonephros development, proteolysis, regulation of blood pressure, regulation of MAPK cascade, renin-angiotensin regulation of aldosterone production, response to cAMP, response to cGMP, response to immobilization stress, response to lipopolysaccharide |
| PubMed |
2016271
|
| Total Prosequence Length (aa) |
43 |
| Prosequence Location |
24:66 |
| Prosequence Sequence |
LPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKR |
| Preproprotein Sequence |
MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR |
