Details of PSQ00680
| ProSeqID |
PSQ00680 |
| Family |
FD00300 |
| Protein Name |
Tissue-type plasminogen activator |
| UniProt ID |
P00750
|
| Taxonomy |
Eukaryota-Metazoa-Chordata-Craniata-Vertebrata-Euteleostomi-Mammalia-Eutheria-Euarchontoglires-Primates-Haplorrhini-Catarrhini-Hominidae-Homo |
| Organisms |
Homo sapiens (Human) |
| Prosequence Length (aa) |
10 |
| Functions |
phosphoprotein binding, serine-type endopeptidase activity, signaling receptor binding |
| Preproprotein Length (aa) |
562 |
| Alt Name |
None |
| Gene Name |
PLAT |
| NCBI ID |
9606 |
| Cellular Localization |
cell surface, cytoplasm, extracellular exosome, extracellular region, extracellular space |
| Processes |
blood coagulation, cellular protein modification process, fibrinolysis, negative regulation of proteolysis, plasminogen activation, platelet-derived growth factor receptor signaling pathway, prevention of polyspermy, proteolysis, smooth muscle cell migration |
| PubMed |
6682760
|
| Total Prosequence Length (aa) |
10 |
| Prosequence Location |
23:32 |
| Prosequence Sequence |
SQEIHARFRR |
| Preproprotein Sequence |
MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP |
