Family ID	FD00534
Protein Name	Apoptosis-inducing factor 1
UniProt ID	O95831
Prosequence Length Range (aa)	47
Preproprotein Length Range(aa)	613
Preproprotein pI Range	9.04
Preproprotein Molecular Weight Range (D)	66900.61
Prosequence pI Range (D)	8.34
Prosequence Molecular Weight Range	4864.46
Domains	cl25936 : pfam07992 : pfam14721
Organisms	Homo sapiens (Human)
Functions	DNA binding; FAD binding; NAD(P)H oxidase H2O2-forming activity; NADH dehydrogenase activity; oxidoreductase activity; acting on NAD(P)H; protein dimerization activity
Cellular Localization	cytosol; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion; nucleus; perinuclear region of cytoplasm
Processes	activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic process; chromosome condensation; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; mitochondrial respiratory chain complex assembly; mitochondrial respiratory chain complex I assembly; neuron differentiation; positive regulation of apoptotic process; protein import into mitochondrial intermembrane space
Common Name	Apoptosis inducing factor