Details of family id : FD00508
| Family ID |
FD00508 |
| Protein Name |
Collagen alpha-1(I) chain |
| UniProt ID |
P02454
|
| Prosequence Length Range (aa) |
129
|
| Preproprotein Length Range(aa) |
1453 |
| Preproprotein pI Range |
5.71 |
| Preproprotein Molecular Weight Range (D) |
137953.45 |
| Prosequence pI Range (D) |
4.28 |
| Prosequence Molecular Weight Range |
13135.74 |
| Domains |
cl35613 : pfam01391 : pfam01391 : pfam01410 : smart00214 |
| Organisms |
Rattus norvegicus (Rat) |
| Functions |
extracellular matrix structural constituent; identical protein binding; metal ion binding; platelet-derived growth factor binding; protease binding |
| Cellular Localization |
collagen trimer; collagen type I trimer; cytoplasm; endoplasmic reticulum; extracellular matrix; extracellular region; extracellular space; Golgi apparatus; secretory granule |
| Processes |
blood vessel development; bone trabecula formation; cartilage development involved in endochondral bone morphogenesis; cellular response to amino acid stimulus; cellular response to epidermal growth factor stimulus; cellular response to fibroblast growth factor stimulus; cellular response to fluoride; cellular response to mechanical stimulus; cellular response to retinoic acid; cellular response to transforming growth factor beta stimulus; cellular response to tumor necrosis factor; cellular response to vitamin E; collagen biosynthetic process; collagen fibril organization; collagen-activated tyrosine kinase receptor signaling pathway; embryonic skeletal system development; endochondral ossification; extracellular matrix organization; face morphogenesis; intramembranous ossification; negative regulation of cell-substrate adhesion; ossification; osteoblast differentiation; positive regulation of canonical Wnt signaling pathway; positive regulation of cell migration; positive regulation of epithelial to mesenchymal transition; positive regulation of transcription; DNA-templated; protein localization to nucleus; protein transport; response to cAMP; response to corticosteroid; response to drug; response to estradiol; response to fluoride; response to hydrogen peroxide; response to hyperoxia; response to mechanical stimulus; response to nutrient; response to nutrient levels; response to peptide hormone; response to steroid hormone; sensory perception of sound; skeletal system development; skeletal system morphogenesis; skin development; skin morphogenesis; tooth eruption; tooth mineralization; visual perception; wound healing |
| Common Name |
Collagen alpha chain |
