Details of family id : FD00433
| Family ID |
FD00433 |
| Protein Name |
Fibrillin-1 |
| UniProt ID |
P35555
|
| Prosequence Length Range (aa) |
20
|
| Preproprotein Length Range(aa) |
2878 |
| Preproprotein pI Range |
4.81 |
| Preproprotein Molecular Weight Range (D) |
312297.52 |
| Prosequence pI Range (D) |
9.98 |
| Prosequence Molecular Weight Range |
2157.37 |
| Domains |
cl00057 : cl39554 : pfam00683 : pfam00683 : pfam00683 : pfam00683 : pfam00683 : pfam00683 : pfam00683 : pfam12947 : pfam12947 : smart00179 |
| Organisms |
Homo sapiens (Human) |
| Functions |
calcium ion binding; extracellular matrix constituent conferring elasticity; extracellular matrix structural constituent; heparin binding; hormone activity; identical protein binding; integrin binding; protein-containing complex binding |
| Cellular Localization |
basement membrane; collagen-containing extracellular matrix; endoplasmic reticulum lumen; extracellular matrix; extracellular region; extracellular space; microfibril |
| Processes |
activation of protein kinase A activity; anatomical structure morphogenesis; camera-type eye development; cell adhesion mediated by integrin; cellular protein metabolic process; cellular response to insulin-like growth factor stimulus; cellular response to transforming growth factor beta stimulus; embryonic eye morphogenesis; extracellular matrix organization; glucose homeostasis; glucose metabolic process; heart development; metanephros development; negative regulation of osteoclast development; negative regulation of osteoclast differentiation; post-embryonic eye morphogenesis; post-translational protein modification; protein kinase A signaling; sequestering of BMP in extracellular matrix; sequestering of TGFbeta in extracellular matrix; skeletal system development |
| Common Name |
Fibrillin |
