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Details of family id : FD00432

Family ID FD00432
Protein Name Pro-glucagon
UniProt ID P01275
Prosequence Length Range (aa) 6
Preproprotein Length Range(aa) 180
Preproprotein pI Range 5.85
Preproprotein Molecular Weight Range (D) 20909.21
Prosequence pI Range (D) 9.75
Prosequence Molecular Weight Range 700.75
Domains pfam00123 : pfam00123 : pfam00123
Organisms Homo sapiens (Human)
Functions glucagon receptor binding; hormone activity; identical protein binding; signaling receptor binding
Cellular Localization endoplasmic reticulum lumen; extracellular region; extracellular space; secretory granule lumen
Processes adenylate cyclase-activating G protein-coupled receptor signaling pathway; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; cellular response to glucagon stimulus; feeding behavior; G protein-coupled receptor signaling pathway; glucose homeostasis; negative regulation of apoptotic process; negative regulation of execution phase of apoptosis; negative regulation of inflammatory response to antigenic stimulus; positive regulation of calcium ion import; positive regulation of ERK1 and ERK2 cascade; positive regulation of gluconeogenesis; positive regulation of histone H3-K4 methylation; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-threonine phosphorylation; positive regulation of protein binding; positive regulation of protein kinase activity; protein kinase A signaling; regulation of insulin secretion; response to activity
Common Name glucagon