Details of family id : FD00432
Family ID |
FD00432 |
Protein Name |
Pro-glucagon |
UniProt ID |
P01275
|
Prosequence Length Range (aa) |
6
|
Preproprotein Length Range(aa) |
180 |
Preproprotein pI Range |
5.85 |
Preproprotein Molecular Weight Range (D) |
20909.21 |
Prosequence pI Range (D) |
9.75 |
Prosequence Molecular Weight Range |
700.75 |
Domains |
pfam00123 : pfam00123 : pfam00123 |
Organisms |
Homo sapiens (Human) |
Functions |
glucagon receptor binding; hormone activity; identical protein binding; signaling receptor binding |
Cellular Localization |
endoplasmic reticulum lumen; extracellular region; extracellular space; secretory granule lumen |
Processes |
adenylate cyclase-activating G protein-coupled receptor signaling pathway; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; cellular response to glucagon stimulus; feeding behavior; G protein-coupled receptor signaling pathway; glucose homeostasis; negative regulation of apoptotic process; negative regulation of execution phase of apoptosis; negative regulation of inflammatory response to antigenic stimulus; positive regulation of calcium ion import; positive regulation of ERK1 and ERK2 cascade; positive regulation of gluconeogenesis; positive regulation of histone H3-K4 methylation; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-threonine phosphorylation; positive regulation of protein binding; positive regulation of protein kinase activity; protein kinase A signaling; regulation of insulin secretion; response to activity |
Common Name |
glucagon |