Details of family id : FD00420
| Family ID |
FD00420 |
| Protein Name |
Appetite-regulating hormone |
| UniProt ID |
Q9QYH7
|
| Prosequence Length Range (aa) |
24
|
| Preproprotein Length Range(aa) |
120 |
| Preproprotein pI Range |
5.62 |
| Preproprotein Molecular Weight Range (D) |
13176.09 |
| Prosequence pI Range (D) |
4.14 |
| Prosequence Molecular Weight Range |
2806.98 |
| Domains |
pfam04643 : pfam04644 |
| Organisms |
Rattus norvegicus (Rat) |
| Functions |
G protein-coupled receptor binding; ghrelin receptor binding; growth hormone-releasing hormone activity; hormone activity; protein tyrosine kinase activator activity |
| Cellular Localization |
axon; cytoplasm; extracellular region; extracellular space; glutamatergic synapse; postsynapse; Schaffer collateral - CA1 synapse |
| Processes |
actin polymerization or depolymerization; activation of MAPK activity; adult feeding behavior; decidualization; dendrite development; energy homeostasis; excitatory postsynaptic potential; G protein-coupled receptor signaling pathway; gastric acid secretion; gastric emptying; negative regulation of apoptotic process; negative regulation of circadian sleep/wake cycle; REM sleep; negative regulation of endothelial cell proliferation; negative regulation of inflammatory response; negative regulation of insulin secretion; negative regulation of interleukin-1 beta production; negative regulation of interleukin-6 production; negative regulation of locomotion; negative regulation of tumor necrosis factor production; positive regulation of adipose tissue development; positive regulation of appetite; positive regulation of bone development; positive regulation of circadian sleep/wake cycle; non-REM sleep; positive regulation of cold-induced thermogenesis; positive regulation of corticotropin secretion; positive regulation of cortisol secretion; positive regulation of cytosolic calcium ion concentration; positive regulation of eating behavior; positive regulation of feeding behavior; positive regulation of gastric mucosal blood circulation; positive regulation of gastro-intestinal system smooth muscle contraction; positive regulation of growth; positive regulation of growth hormone secretion; positive regulation of growth rate; positive regulation of insulin secretion; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of response to food; positive regulation of small intestinal transit; positive regulation of small intestine smooth muscle contraction; positive regulation of sprouting angiogenesis; positive regulation of synapse assembly; positive regulation of vascular endothelial cell proliferation; postsynaptic modulation of chemical synaptic transmission; regulation of cell population proliferation; regulation of gastric motility; regulation of postsynapse organization; regulation of response to food; regulation of transmission of nerve impulse; response to electrical stimulus; response to estrogen; response to hormone; response to nutrient levels |
| Common Name |
Appetite regulating hormone |
